Zobrazeno 1 - 10
of 32
pro vyhledávání: '"Stig O. P. Jacobsson"'
Publikováno v:
BMC Pharmacology and Toxicology, Vol 18, Iss 1, Pp 1-11 (2017)
Abstract Background Exposure to chemicals might be toxic to the developing brain. There is a need for simple and robust in vitro cellular models for evaluation of chemical-induced neurotoxicity as a complement to traditional studies on animals. In th
Externí odkaz:
https://doaj.org/article/d262b54aff564407a752b7e214dac904
Publikováno v:
PLoS ONE, Vol 11, Iss 11, p e0166750 (2016)
3,4-methylenedioxymethamphetamine (MDMA; ecstasy) is a commonly abused recreational drug that causes neurotoxic effects in both humans and animals. The mechanism behind MDMA-induced neurotoxicity is suggested to be species-dependent and needs to be f
Externí odkaz:
https://doaj.org/article/6824adfc5a0f458286cae36b6c8c7d88
Publikováno v:
PLoS ONE, Vol 9, Iss 1, p e87542 (2014)
The antifungal compound ketoconazole has, in addition to its ability to interfere with fungal ergosterol synthesis, effects upon other enzymes including human CYP3A4, CYP17, lipoxygenase and thromboxane synthetase. In the present study, we have inves
Externí odkaz:
https://doaj.org/article/146905c8bdc64aabb1fb10bcf1d9f4ca
Autor:
Sofia B Gustafsson, Richard Palmqvist, Maria L Henriksson, Anna M Dahlin, Sofia Edin, Stig O P Jacobsson, Åke Öberg, Christopher J Fowler
Publikováno v:
PLoS ONE, Vol 6, Iss 8, p e23003 (2011)
BackgroundThere is good evidence in the literature that the cannabinoid system is disturbed in colorectal cancer. In the present study, we have investigated whether CB(1) receptor immunoreactive intensity (CB(1)IR intensity) is associated with diseas
Externí odkaz:
https://doaj.org/article/2f94b9e5d28d4124b610b54a3ffed347
Publikováno v:
Scientific Reports, Vol 9, Iss 1, Pp 1-8 (2019)
Scientific Reports
Scientific Reports
We have examined the effects of the synthetic cannabinoids HU 210 and HU 211, the plant-derived cannabidiol and the endogenous cannabinoid anandamide on the viability and development of chick embryos. Fertilized White Leghorn chicken eggs were inject
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f8dac67481794c46c053e6b0fb5a4a19
http://urn.kb.se/resolve?urn=urn:nbn:se:umu:diva-51558
http://urn.kb.se/resolve?urn=urn:nbn:se:umu:diva-51558
Publikováno v:
BMC Pharmacology & Toxicology
BMC Pharmacology and Toxicology, Vol 18, Iss 1, Pp 1-11 (2017)
BMC Pharmacology and Toxicology, Vol 18, Iss 1, Pp 1-11 (2017)
Background: Exposure to chemicals might be toxic to the developing brain. There is a need for simple and robust in vitro cellular models for evaluation of chemical-induced neurotoxicity as a complement to traditional studies on animals. In this study
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0bcde58f9f94628d02cf94447e4ca895
http://europepmc.org/articles/PMC5460426
http://europepmc.org/articles/PMC5460426
Publikováno v:
PLoS ONE
PLoS ONE, Vol 11, Iss 11, p e0166750 (2016)
PLoS ONE, Vol 11, Iss 11, p e0166750 (2016)
3,4-methylenedioxymethamphetamine (MDMA; ecstasy) is a commonly abused recreational drug that causes neurotoxic effects in both humans and animals. The mechanism behind MDMA-induced neurotoxicity is suggested to be species-dependent and needs to be f
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4ed3b922432c3eb63e9bfc50746df7d2
http://urn.kb.se/resolve?urn=urn:nbn:se:umu:diva-128533
http://urn.kb.se/resolve?urn=urn:nbn:se:umu:diva-128533
Publikováno v:
Toxicology Letters. 207:1-6
It is now well established that nicotine adversely affects the integrity of the blood–brain barrier (BBB). In contrast, nicotine has been reported to increase the transendothelial electrical resist ...
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::f8c23fd62a7e19b3cfb8a2d37301f676
https://doi.org/10.1016/j.toxlet.2011.08.014
https://doi.org/10.1016/j.toxlet.2011.08.014
Autor:
Anders Bergh, Emma Persson, Sofia B. Gustafsson, Christopher J. Fowler, Sui Chu Chung, Stig O. P. Jacobsson
Publikováno v:
Current Topics in Medicinal Chemistry. 10:814-827
In recent years, considerable interest has been generated by findings that cannabinoids not only have useful palliative effects, but also can affect the viability and invasivity of a variety of different cancer cells. In the present review, the poten
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9168a4c58c92fca84322dbe30833a4c8
https://doi.org/10.2174/156802610791164201
https://doi.org/10.2174/156802610791164201
Publikováno v:
Cancer Chemotherapy and Pharmacology. 63:691-701
Cannabinoids (CBs) have been found to exert antiproliferative effects upon a variety of cancer cells, including colorectal carcinoma cells. However, little is known about the signalling mechanisms behind the antitumoural effect in these cells, whethe
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cb42d2e7ccf3c3ba88dfe72709edd0b1
https://doi.org/10.1007/s00280-008-0788-5
https://doi.org/10.1007/s00280-008-0788-5