Výsledky vyhledávání - "Stig M. R. Jensen"

Akademický článek

Mycobacterial antigen driven activation of CD14++CD16- monocytes is a predictor of tuberculosis-associated immune reconstitution inflammatory syndrome.

Autor: Bruno B Andrade, Amrit Singh, Gopalan Narendran, Melissa E Schechter, Kaustuv Nayak, Sudha Subramanian, Selvaraj Anbalagan, Stig M R Jensen, Brian O Porter, Lis R Antonelli, Katalin A Wilkinson, Robert J Wilkinson, Graeme Meintjes, Helen van der Plas, Dean Follmann, Daniel L Barber, Soumya Swaminathan, Alan Sher, Irini Sereti

Publikováno v: PLoS Pathogens, Vol 10, Iss 10, p e1004433 (2014)

Paradoxical tuberculosis-associated immune reconstitution inflammatory syndrome (TB-IRIS) is an aberrant inflammatory response occurring in a subset of TB-HIV co-infected patients initiating anti-retroviral therapy (ART). Here, we examined monocyte a

Externí odkaz: https://doaj.org/article/7ae61a2319924ea2a5845cec9905c6e5

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A Smartphone-Based Rapid Telemonitoring System for Ebola and Marburg Disease Surveillance

Autor: Beverly Dyas, Onur Mudanyali, Neven Karlovac, Sz-Wei Wu, Mohan Natesan, Stig M. R. Jensen, Robert G. Ulrich, Chieh-I Chen

Publikováno v: ACS Sensors

We have developed a digital and multiplexed platform for the rapid detection and telemonitoring of infections caused by Ebola and Marburg filoviruses. The system includes a flow cell assay cartridge that captures specific antibodies with microarrayed

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::44eebd78435a9075288d778ac71e13f7
https://pubmed.ncbi.nlm.nih.gov/30525467

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Antibody Responses to Zika Virus Infections in Environments of Flavivirus Endemicity

Autor: David H. O’Connor, Jessica L. Smith, Stig M. R. Jensen, Robert D. Hontz, Dawn M. Dudley, Robert G. Ulrich, Sarah L. Keasey, Christine Pugh, Anna P. Durbin

Publikováno v: Clinical and Vaccine Immunology. 24

Zika virus (ZIKV) infections occur in areas where dengue virus (DENV), West Nile virus (WNV), yellow fever virus (YFV), and other viruses of the genus Flavivirus cocirculate. The envelope (E) proteins of these closely related flaviviruses induce spec

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a1f8fbf9910ae92edd35f6e7ecbc22c6
https://doi.org/10.1128/cvi.00036-17

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Differential Inhibitory Effects of Cyanovirin-N, Griffithsin, and Scytovirin on Entry Mediated by Envelopes of Gammaretroviruses and Deltaretroviruses

Autor: Kathryn S. Jones, Daniel C. Bertolette, Barry R. O'Keefe, Alan Rein, Francis W. Ruscetti, Carrie J. Saucedo, Stig M. R. Jensen

Publikováno v: Journal of Virology

The antiviral lectins griffithsin (GRFT), cyanovirin-N (CV-N), and scytovirin (SVN), which inhibit several enveloped viruses, including lentiviruses, were examined for their ability to inhibit entry mediated by Env proteins of delta- and gammaretrovi

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ae21876852902a5339371ebae6beec90

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Surface functionalisation of PLGA nanoparticles for gene silencing

Autor: Morten Østergaard Andersen, Stig M. R. Jensen, Kenneth A. Howard, Flemming Besenbacher, Harpreet Kaur, Agata Lichawska, David Oupicky, Jørgen Kjems, Ayyoob Arpanaei, Peter Kingshott

Publikováno v: Andersen, M Ø, Lichawska, A, Arpanaei, A, Jensen, S M R, Kaur, H, Oupicky, D, Besenbacher, F, Kingshott, P, Kjems, J & Howard, K A 2010, ' Surface functionalisation of PLGA nanoparticles for gene silencing ', Biomaterials, vol. 31, no. 21, pp. 5671-5677 . https://doi.org/10.1016/j.biomaterials.2010.03.069

This work presents a method for decorating the surface of poly (lactide-co-glycolide) (PLGA) nanoparticles with polyethyleneimine (PEI) utilising a cetyl derivative to improve surface functionalisation and siRNA delivery. Sub-micron particles were pr

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b0f649567e81269b43f2a2f038a56d1c
https://doi.org/10.1016/j.biomaterials.2010.03.069

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Microprocessor dynamics and interactions at endogenous imprinted C19MC microRNA genes

Autor: Stig M. R. Jensen, Ute Schmidt, Marie-line Bortolin-Cavaillé, Edouard Bertrand, Jørgen Kjems, Jérôme Cavaillé, Clément Bellemer

Publikováno v: Bellemer, C, Bortolin-Cavaillé, M-L, Schmidt, U, Jensen, S M R, Kjems, J, Bertrand, E & Cavaillé, J 2012, ' Microprocessor dynamics and interactions at endogenous imprinted C19MC microRNA genes ', Journal of Cell Science, vol. 125, pp. 2709-2720 . https://doi.org/10.1242/jcs.100354
Journal of Cell Science
Journal of Cell Science, Company of Biologists, 2012, pp.2709-2720. ⟨10.1242/jcs.100354⟩
Journal of Cell Science, Company of Biologists, 2012, epub ahead of print. 〈10.1242/jcs.100354〉

International audience; Nuclear primary microRNA (pri-miRNA) processing catalyzed by the DGCR8-Drosha (Microprocessor) complex is highly regulated. Little is known, however, about how microRNA biogenesis is spatially organized within the mammalian nu

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9a9a2bf021a1b9fa124baf4801549e24
https://pure.au.dk/portal/da/publications/microprocessor-dynamics-and-interactions-at-endogenous-imprinted-c19mc-microrna-genes(126e79b6-971e-486f-ab8a-71dc3356f1a1).html

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Functional selection of shRNA loops from randomized retroviral libraries

Autor: Jesper B. Bramsen, Stig M. R. Jensen, Alexander Schmitz, Jørgen Kjems, Finn Skou Pedersen

Publikováno v: Jensen, S M R, Schmitz, A, Pedersen, F S, Kjems, J & Bramsen, J B 2012, ' Functional selection of shRNA loops from randomized retroviral libraries ', P L o S One, vol. 7, no. 8, pp. e43095 . https://doi.org/10.1371/journal.pone.0043095
PLoS ONE
PLoS ONE, Vol 7, Iss 8, p e43095 (2012)

Gene silencing by RNA interference (RNAi) can be achieved by the ectopic expression of tailored short hairpin RNAs (shRNAs) which after export to the cytoplasm are processed by Dicer and incorporated into the RNA induced silencing complex (RISC). Des

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2f75d2d049975db5ed6ff11d352e66df
https://pure.au.dk/portal/da/publications/functional-selection-of-shrna-loops-from-randomized-retroviral-libraries(9161748b-e4e0-4e00-9a4e-9d4b8ee0119e).html

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Enhanced yellow fluorescent protein photoconversion to a cyan fluorescent protein-like species is sensitive to thermal and diffusion conditions

Autor: Maj M. Kjaergaard, Hanne Poulsen, Stig M. R. Jensen, Heidi Kaastrup Müller, Anja W. Fjorback, Merete K. Raarup, Ove Wiborg, Jens R. Nyengaard

Publikováno v: Raarup, M K, Fjorback, A W, Jensen, S M R, Müller, H K, Kjaergaard, M M, Poulsen, H, Wiborg, O & Nyengaard, J R 2009, ' Enhanced yellow fluorescent protein photoconversion to a cyan fluorescent protein-like species is sensitive to thermal and diffusion conditions ', Journal of Biomedical Optics, vol. 14, no. 3, pp. 034039 . https://doi.org/10.1117/1.3103338

Udgivelsesdato: null-null Ongoing research efforts into fluorescent proteins continuously generates new mutation variants, some of which can become photoactivated or photoconverted to a red-shifted color upon intense UV or blue light illumination. We

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c35c6b163935fd62f272e30969e542a7
https://pure.au.dk/portal/da/publications/enhanced-yellow-fluorescent-protein-photoconversion-to-a-cyan-fluorescent-proteinlike-species-is-sensitive-to-thermal-and-diffusion-conditions(56d3a140-b720-11de-a554-000ea68e967b).html

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Different routes of entry of HTLV-1 during infection of primary dendritic cells and CD4+ T cells

Autor: Nabela Enam, Cari Petrow-Sadowski, Daniel C. Bertolette, Kathryn S. Jones, Rachel Bagni, Francis W. Ruscetti, Stig M. R. Jensen, Robert Yarchoan, David A. Davis

Publikováno v: Retrovirology

Although HTLV-1 is primarily found in T cells in infected individuals, ex vivo cultures of T cells are not readily infected by cell-free HTLV-1. In contrast, cell-free HTLV-1 efficiently infects cultures of primary dendritic cells. Little is known ab

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::91611a49db4b06c7f9a261f7d863ff1c

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