Zobrazeno 1 - 10
of 255
pro vyhledávání: '"Stig HaunsØ"'
Autor:
Rosalie B. T. M. Sterenborg, Inga Steinbrenner, Yong Li, Melissa N. Bujnis, Tatsuhiko Naito, Eirini Marouli, Tessel E. Galesloot, Oladapo Babajide, Laura Andreasen, Arne Astrup, Bjørn Olav Åsvold, Stefania Bandinelli, Marian Beekman, John P. Beilby, Jette Bork-Jensen, Thibaud Boutin, Jennifer A. Brody, Suzanne J. Brown, Ben Brumpton, Purdey J. Campbell, Anne R. Cappola, Graziano Ceresini, Layal Chaker, Daniel I. Chasman, Maria Pina Concas, Rodrigo Coutinho de Almeida, Simone M. Cross, Francesco Cucca, Ian J. Deary, Alisa Devedzic Kjaergaard, Justin B. Echouffo Tcheugui, Christina Ellervik, Johan G. Eriksson, Luigi Ferrucci, Jan Freudenberg, GHS DiscovEHR, Regeneron Genetics Center, Christian Fuchsberger, Christian Gieger, Franco Giulianini, Martin Gögele, Sarah E. Graham, Niels Grarup, Ivana Gunjača, Torben Hansen, Barbara N. Harding, Sarah E. Harris, Stig Haunsø, Caroline Hayward, Jennie Hui, Till Ittermann, J. Wouter Jukema, Eero Kajantie, Jørgen K. Kanters, Line L. Kårhus, Lambertus A. L. M. Kiemeney, Margreet Kloppenburg, Brigitte Kühnel, Jari Lahti, Claudia Langenberg, Bruno Lapauw, Graham Leese, Shuo Li, David C. M. Liewald, Allan Linneberg, Jesus V. T. Lominchar, Jian’an Luan, Nicholas G. Martin, Antonela Matana, Marcel E. Meima, Thomas Meitinger, Ingrid Meulenbelt, Braxton D. Mitchell, Line T. Møllehave, Samia Mora, Silvia Naitza, Matthias Nauck, Romana T. Netea-Maier, Raymond Noordam, Casia Nursyifa, Yukinori Okada, Stefano Onano, Areti Papadopoulou, Colin N. A. Palmer, Cristian Pattaro, Oluf Pedersen, Annette Peters, Maik Pietzner, Ozren Polašek, Peter P. Pramstaller, Bruce M. Psaty, Ante Punda, Debashree Ray, Paul Redmond, J. Brent Richards, Paul M. Ridker, Tom C. Russ, Kathleen A. Ryan, Morten Salling Olesen, Ulla T. Schultheiss, Elizabeth Selvin, Moneeza K. Siddiqui, Carlo Sidore, P. Eline Slagboom, Thorkild I. A. Sørensen, Enrique Soto-Pedre, Tim D. Spector, Beatrice Spedicati, Sundararajan Srinivasan, John M. Starr, David J. Stott, Toshiko Tanaka, Vesela Torlak, Stella Trompet, Johanna Tuhkanen, André G. Uitterlinden, Erik B. van den Akker, Tibbert van den Eynde, Melanie M. van der Klauw, Diana van Heemst, Charlotte Verroken, W. Edward Visser, Dina Vojinovic, Henry Völzke, Melanie Waldenberger, John P. Walsh, Nicholas J. Wareham, Stefan Weiss, Cristen J. Willer, Scott G. Wilson, Bruce H. R. Wolffenbuttel, Hanneke J. C. M. Wouters, Margaret J. Wright, Qiong Yang, Tatijana Zemunik, Wei Zhou, Gu Zhu, Sebastian Zöllner, Johannes W. A. Smit, Robin P. Peeters, Anna Köttgen, Alexander Teumer, Marco Medici
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-18 (2024)
Abstract To date only a fraction of the genetic footprint of thyroid function has been clarified. We report a genome-wide association study meta-analysis of thyroid function in up to 271,040 individuals of European ancestry, including reference range
Externí odkaz:
https://doaj.org/article/87582eb11e3e4880b14ffaaf73048c8f
Autor:
Oliver Bundgaard Vad, Yannan Yan, Federico Denti, Gustav Ahlberg, Lena Refsgaard, Sofia Hammami Bomholtz, Joana Larupa Santos, Simon Rasmussen, Stig Haunsø, Jesper Hastrup Svendsen, Ingrid Elizabeth Christophersen, Nicole Schmitt, Morten Salling Olesen, Bo Hjorth Bentzen
Publikováno v:
Frontiers in Genetics, Vol 13 (2022)
Background: Atrial Fibrillation (AF) is the most prevalent sustained cardiac arrhythmia, responsible for considerable morbidity and mortality. The heterogenic and complex pathogenesis of AF remains poorly understood, which contributes to the current
Externí odkaz:
https://doaj.org/article/82f682a38dfe4ee1a45677fb8038a829
Autor:
Gustav Ahlberg, Lena Refsgaard, Pia R. Lundegaard, Laura Andreasen, Mattis F. Ranthe, Nora Linscheid, Jonas B. Nielsen, Mads Melbye, Stig Haunsø, Ahmad Sajadieh, Lu Camp, Søren-Peter Olesen, Simon Rasmussen, Alicia Lundby, Patrick T. Ellinor, Anders G. Holst, Jesper H. Svendsen, Morten S. Olesen
Publikováno v:
Nature Communications, Vol 9, Iss 1, Pp 1-11 (2018)
Common genetic variants in structural proteins contribute to risk of atrial fibrillation (AF). Here, using whole-exome sequencing, the authors identify rare truncating variants in TTN that associate with familial and early-onset AF and show defects i
Externí odkaz:
https://doaj.org/article/32b75a989a0d494f99383ba50d107a85
Autor:
Reza Jabbari, Javad Jabbari, Charlotte Glinge, Bjarke Risgaard, Stefan Sattler, Bo Gregers Winkel, Christian Juhl Terkelsen, Hans-Henrik Tilsted, Lisette Okkels Jensen, Mikkel Hougaard, Stig Haunsø, Thomas Engstrøm, Christine M. Albert, Jacob Tfelt-Hansen
Publikováno v:
BMC Medical Genetics, Vol 18, Iss 1, Pp 1-6 (2017)
Abstract Background Cohort studies have revealed an increased risk for ventricular fibrillation (VF) and sudden cardiac death (SCD) in patients with atrial fibrillation (AF). In this study, we hypothesized that single nucleotide polymorphisms (SNP) p
Externí odkaz:
https://doaj.org/article/a16e21d87a6742e7bf6838d57e9ce28a
Autor:
Christian Torp-Pedersen, Lars Køber, Marc Meller Søndergaard, Jonas Bille Nielsen, Rikke Nørmark Mortensen, Gunnar Gislason, Freddy Lippert, Claus Graff, Stig Haunsø, Jesper Hastrup Svendsen, Kristian Hay Kragholm, Adrian Holger Pietersen, Bent Struer Lind, Søren Pihlkjær Hjortshøj, Anders Gaarsdal Holst, Johannes Jan Struijk, Steen Møller Hansen
Publikováno v:
Open Heart, Vol 6, Iss 1 (2019)
Background Out-of-hospital cardiac arrest (OHCA) is often the first manifestation of unrecognised cardiac disease. ECG abnormalities encountered in primary care settings may be warning signs of OHCA.Objective We examined the association between commo
Externí odkaz:
https://doaj.org/article/ca9a872892594a44ae32e41a136ccbe5
Autor:
Laura Andreasen, Jonas Ghouse, Morten W. Skov, Christian T. Have, Gustav Ahlberg, Peter V. Rasmussen, Allan Linneberg, Oluf Pedersen, Pyotr G. Platonov, Stig Haunsø, Jesper H. Svendsen, Torben Hansen, Jørgen K. Kanters, Morten S. Olesen
Publikováno v:
Frontiers in Physiology, Vol 9 (2018)
Introduction: A previous genome-wide association study found three genetic loci, rs9388451, rs10428132, and rs11708996, to increase the risk of Brugada Syndrome (BrS). Since the effect of these loci in the general population is unknown, we aimed to i
Externí odkaz:
https://doaj.org/article/b6c39aa0ff3241b69e27e161ab12d15c
Autor:
Morten W. Skov, Jonas Ghouse, Jørgen T. Kühl, Pyotr G. Platonov, Claus Graff, Andreas Fuchs, Peter V. Rasmussen, Adrian Pietersen, Børge G. Nordestgaard, Christian Torp‐Pedersen, Steen M. Hansen, Morten S. Olesen, Stig Haunsø, Lars Køber, Thomas A. Gerds, Klaus F. Kofoed, Jesper H. Svendsen, Anders G. Holst, Jonas B. Nielsen
Publikováno v:
Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease, Vol 7, Iss 11 (2018)
BackgroundThe electrocardiographic interatrial block (IAB) has been associated with atrial fibrillation (AF). We aimed to test whether IAB can improve risk prediction of AF for the individual person. Methods and ResultsDigital ECGs of 152 759 primary
Externí odkaz:
https://doaj.org/article/7963d72bd1364e259fec4727803a9609
Autor:
Reza Jabbari, Charlotte Glinge, Javad Jabbari, Bjarke Risgaard, Bo Gregers Winkel, Christian Juhl Terkelsen, Hans-Henrik Tilsted, Lisette Okkels Jensen, Mikkel Hougaard, Stig Haunsø, Thomas Engstrøm, Christine M Albert, Jacob Tfelt-Hansen
Publikováno v:
PLoS ONE, Vol 12, Iss 1, p e0170193 (2017)
Several common genetic variants have been associated with either ventricular fibrillation (VF) or sudden cardiac death (SCD). However, replication efforts have been limited. Therefore, we aimed to analyze whether such variants may contribute to VF ca
Externí odkaz:
https://doaj.org/article/3e5c68d49e384c87b7eac17585ee7441
Autor:
Marie Mi Bonde, Jonas Tind Hansen, Samra Joke Sanni, Stig Haunsø, Steen Gammeltoft, Christina Lyngsø, Jakob Lerche Hansen
Publikováno v:
PLoS ONE, Vol 5, Iss 11, p e14135 (2010)
Seven transmembrane receptors (7TMRs) can adopt different active conformations facilitating a selective activation of either G protein or β-arrestin-dependent signaling pathways. This represents an opportunity for development of novel therapeutics t
Externí odkaz:
https://doaj.org/article/86819fd62a8e44de89068ff9032481c4
Autor:
Henning Bundgaard, Morten S. Olesen, Jonas Ghouse, Laura Andreasen, Jesper Hastrup Svendsen, Stig Haunsø, Gustav Ahlberg, Litten Bertelsen
Publikováno v:
European Heart Journal
Ahlberg, G, Andreasen, L, Ghouse, J, Bertelsen, L, Bundgaard, H, Haunsø, S, Svendsen, J H & Olesen, M S 2021, ' Genome-wide association study identifies 18 novel loci associated with left atrial volume and function ', European Heart Journal, vol. 42, no. 44, pp. 4523–4534 . https://doi.org/10.1093/eurheartj/ehab466
Ahlberg, G, Andreasen, L, Ghouse, J, Bertelsen, L, Bundgaard, H, Haunsø, S, Svendsen, J H & Olesen, M S 2021, ' Genome-wide association study identifies 18 novel loci associated with left atrial volume and function ', European Heart Journal, vol. 42, no. 44, pp. 4523–4534 . https://doi.org/10.1093/eurheartj/ehab466
Aims Left atrial (LA) volume and function impose significant impact on cardiovascular pathogenesis if compromised. We aimed at investigating the genetic architecture of LA volume and function using cardiac magnetic resonance imaging data. Methods and