Zobrazeno 1 - 10
of 65
pro vyhledávání: '"Stig Agurell"'
Autor:
Stig Agurell
Publikováno v:
Ciba Foundation Symposium 26 - The Poisoned Patient: The Role of the Laboratory
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::d3a4eb7c1cb5a0f7fc010990a909adb1
https://doi.org/10.1002/9780470720080.ch8
https://doi.org/10.1002/9780470720080.ch8
Publikováno v:
Marihuana and Medicine ISBN: 9781475757170
A strict chemical nomenclature is first proposed. It is based on the definitions of cannabinoids, psychoactive (THC) and nonpsychoactive (CBD, CBN, and THC-11 oic acid), and of identified receptors (AEA and G protein) and their physiological ligands
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::371cbae52fff555f2c3147d9262e7c44
https://doi.org/10.1007/978-1-59259-710-9_78
https://doi.org/10.1007/978-1-59259-710-9_78
Autor:
Kurt Leander, Bill Martin, Marianne Nordqvist, Michael Binder, Stig Agurell, Jan-Erik Lindgren
Publikováno v:
Journal of Pharmacy and Pharmacology. 28:275-279
Cannabidiol (CBD) was metabolized in vitro by rat liver enzymes. Unchanged CBD and eight monohydroxylated metabolites were isolated and positively identified. As previously reported, 7-hydroxy-CBD was the major metabolite. The second most abundant me
Autor:
Marrianne Nordqvist, Naftali Lander, Stig Agurell, Raphael Mechoulam, Z. Ben-Zvi, Bill Martin
Publikováno v:
J. Chem. Soc., Perkin Trans. 1. :8-16
10-Hydroxycannabidiol [2-(10-hydroxy-p-mentha-1,8-dien-3-yl)-5-pentylresorcinol](Va), which has tentatively been identified as a cannabidiol metabolite, as well as 6α- and 6β-hydroxy-cannabidiol [(VIa) and (VIIa)], which are now reported to be meta
Publikováno v:
Acta Chemica Scandinavica. :1175-1179
Publikováno v:
Acta Chemica Scandinavica. :239-243
Publikováno v:
Journal of Pharmacy and Pharmacology. 31:238-243
The in vivo metabolism of Δ1-trahydrocannabinol (Δ1-THC) was further investigated in the rabbit after i.v. administration. Nine acidic metabolites were isolated from a previously not investigated fraction of the urine and identified by gas chromato
Publikováno v:
Biochemical Pharmacology. 23:1163-1172
Δ1-Tetrahydrocannabinol (Δ1-THC) administered i.v. (1 mg/kg) to anaesthetized rats with cannulated bile ducts is rapidly eliminated as metabolites in the bile. 60–70 per cent in 6 hr. In comparison with the slow excretion via faeces an extensive
Publikováno v:
Journal of Chromatography A. 120:343-348
delta1-Tetrahydrocannabinol, delta6-tetrahydrocannabinol, cannabinol, cannabidiol and several of their monooxygenated derivatives have been separated from each other by a combination of liquid, thin-layer and gas chromatography. Retention volumes (on
Publikováno v:
Helvetica Chimica Acta. 57:1626-1641
The 100-MHz-NMR-spectra of 11 side chain hydroxylated derivatives of cannabidiol (1), Δ6-tetrahydrocannabinol (2) and cannabinol (3) were analysed for signals specific for the position of hydroxyl groups. The mass spectra of these compounds and thei