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Genetic Relationship between Schizophrenia and Nicotine Dependence

Autor: Chen, Jingchun, Bacanu, S. A., Yu, H., Zhao, Z., Jia, P., Kendler, K. S., Kranzler, H. R., Gelernter, J., Farrer, L., Minica, C., Pool, R., Milaneschi, Y., Boomsma, D. I., Penninx, B. W., Tyndale, R. F., Ware, J. J., Vink, J. M., Kaprio, Jaakko, Munafo, M., Chen, X., Loukola, Anu, Mangino, M., Menni, C., Chen, J., Peterson, R., Auro, Kirsi, Lyytikäinen, Leo-Pekka, Wedenoja, Juho, Stiby, A. I., Hemani, G., Willemsen, G., Hottenga, J. J., Korhonen, Tellervo, Heliövaara, Markku, Perola, Markus, Rose, R., Paternoster, L., Timpson, N., Wassenaar, C. A., Zhu, A. Z., Smith, G. D., Raitakari, Olli, Lehtimäki, Terho, Kähönen, Mika, Koskinen, Seppo, Spector, T., Salomaa, Veikko, Taylor, M., Maes, H., Riley, B., Sherva, R., Maher, B., Vanyukov, M.

Publikováno v: Scientific Reports, 6:25671. Nature Publishing Group
Scientific Reports, 6. Nature Publishing Group
Chen, J, Bacanu, S A, Yu, H, Zhao, Z, Jia, P, Kendler, K S, Kranzler, H R, Gelernter, J, Farrer, L, Minica, C C, Pool, R, Milaneschi, Y, Boomsma, D I, Penninx, B W J H, Tyndale, R F, Ware, J J, Vink, J M, Kaprio, J, Munafò, M & Chen, X 2016, ' Genetic Relationship between Schizophrenia and Nicotine Dependence ', Scientific Reports, vol. 6, 25671 . https://doi.org/10.1038/srep25671
Stiby, A, Hemani, G, Paternoster, L & Timpson, N & Davey Smith, G & Taylor, M 2016, ' Genetic Relationship between Schizophrenia and Nicotine Dependence ', Scientific Reports, vol. 6, 25671 . https://doi.org/10.1038/srep25671
Scientific Reports
Scientific Reports, 6
Chen, J, Bacanu, S-A, Yu, H, Zhao, Z, Jia, P, Kendler, K S, Kranzler, H R, Gelernter, J, Farrer, L, Minica, C, Pool, R, Milaneschi, Y, Boomsma, D I, Penninx, B W J H, Tyndale, R F, Ware, J J, Vink, J M, Kaprio, J, Munafo, M & Chen, X 2016, ' Genetic Relationship between Schizophrenia and Nicotine Dependence ', Scientific Reports, vol. 6 . https://doi.org/10.1038/srep25671

It is well known that most schizophrenia patients smoke cigarettes. There are different hypotheses postulating the underlying mechanisms of this comorbidity. We used summary statistics from large meta-analyses of plasma cotinine concentration (COT),

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::20119d97743eb839254e8c07b77cc364
https://doi.org/10.1038/srep25671

Genome-wide association study of lifetime cannabis use based on a large meta-analytic sample of 32 330 subjects from the International Cannabis Consortium

Autor: Stringer, S, Minică, C C, Verweij, K J H, Mbarek, H, Bernard, M, Derringer, J, van Eijk, K R, Isen, J D, Loukola, A, Maciejewski, D F, Mihailov, E, van der Most, P J, Sánchez-Mora, C, Roos, L, Sherva, R, Walters, R, Ware, J J, Abdellaoui, A, Bigdeli, T B, Branje, S J T, Brown, S A, Bruinenberg, M, Casas, M, Esko, T, Garcia-Martinez, I, Gordon, S D, Harris, J M, Hartman, C A, Henders, A K, Heath, A C, Hickie, Ian B, Hickman, M, Hopfer, C J, Hottenga, J J, Huizink, A C, Irons, D E, Kahn, R S, Korhonen, T, Kranzler, H R, Krauter, K, van Lier, P A C, Lubke, G H, Madden, P A F, Mägi, R, McGue, M K, Medland, S E, Meeus, W H J, Miller, M B, Montgomery, G W, Nivard, M G, Nolte, I M, Oldehinkel, A J, Pausova, Z, Qaiser, B, Quaye, L, Ramos-Quiroga, J A, Richarte, V, Rose, R J, Shin, J, Stallings, M C, Stiby, A I, Wall, T L, Wright, M J, Koot, H M, Paus, T, Hewitt, J K, Ribasés, M, Kaprio, J, Boks, M P, Snieder, Harold, Spector, T, Munafò, M R, Metspalu, A, Gelernter, J, Boomsma, D I, Iacono, W G, Martin, N G, Gillespie, N A, Derks, E M, Vink, J M, Universitat Autònoma de Barcelona

Publikováno v: Dipòsit Digital de Documents de la UAB
Universitat Autònoma de Barcelona

Cannabis is the most widely produced and consumed illicit psychoactive substance worldwide. Occasional cannabis use can progress to frequent use, abuse and dependence with all known adverse physical, psychological and social consequences. Individual

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=RECOLECTA___::8944839351fc07d9fc7ab70ce95d5166
https://ddd.uab.cat/record/185832

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