Zobrazeno 1 - 10
of 77
pro vyhledávání: '"Sthanam V.L. Narayana"'
Autor:
Debasish Chattopadhyay, Sthanam V.L. Narayana, Srinivas Chakravarthy, Chungyu Chang, Hung Ton-That, Anna M. Blom, Vaibhav Agarwal, Kartik Manne, Baldeep Khare
Publikováno v:
Acta Crystallogr D Struct Biol
BibA, a group B streptococcus (GBS) surface protein, has been shown to protect the pathogen from phagocytic killing by sequestering a complement inhibitor: C4b-binding protein (C4BP). Here, the X-ray crystallographic structure of a GBS BibA fragment
Publikováno v:
Acta Crystallogr F Struct Biol Commun
The Gram-positive bacteriumStreptococcus pneumoniae, a major human pathogen, is a regular colonizer of the upper and lower respiratory tracts. Pneumococcal adherence and virulence factor A (PavA), a fibronectin-binding bacterial protein, fromS. pneum
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a503b170c7e835833acf897e2ef8aaa7
https://europepmc.org/articles/PMC6777132/
https://europepmc.org/articles/PMC6777132/
Autor:
Sthanam V.L. Narayana, Baldeep Khare
Publikováno v:
Protein Science. 26:1458-1473
Successful adherence, colonization, and survival of Gram-positive bacteria require surface proteins, and multiprotein assemblies called pili. These surface appendages are attractive pharmacotherapeutic targets and understanding their assembly mechani
Autor:
Kartik Manne, Sthanam V.L. Narayana
Publikováno v:
Acta Crystallogr D Struct Biol
Extracellular serine protease (Esp) from Staphylococcus epidermidis is a glutamyl endopeptidase that inhibits the growth and formation of S. aureus biofilms. Previously, crystal structures of the matured and active Esp have been determined. Interesti
Autor:
Kartik Manne, Sthanam V.L. Narayana
The second complement component C2 is a multidomain serine protease that provides catalytic activity to the C3 and C5 convertases of classical and lectin pathways of complement. Formation of these convertases requires the Mg-dependent binding of C2 t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::4b0e343995052ea13c6c5014755b6203
https://doi.org/10.1016/b978-0-12-810420-0.00013-4
https://doi.org/10.1016/b978-0-12-810420-0.00013-4
Autor:
Atul Agarwal, John P. Atkinson, Paul N. Barlow, Scott R. Barnum, Saverio Bettuzzi, Anna M. Blom, Susan A. Boackle, Suzanne Bohlson, Daniel C. Bullard, David M. Cauvi, Maciej Cedzyński, Joseph M. Christy, Liam G. Coulthard, Richard G. DiScipio, Christian Drouet, Viviana P. Ferreira, Zvi Fishelson, Christine Gaboriaud, Arije Ghannam, Berhane Ghebrehiwet, Ionita Ghiran, Owen A. Hawksworth, Mingjun Huang, David E. Isenman, Jens C. Jensenius, Claudia Kemper, David C. Kilpatrick, Jennifer Laskowski, M. Kathryn Liszewski, Kartik Manne, Misao Matsushita, Paul Morgan, Valeria Naponelli, Sthanam V.L. Narayana, Anne Nicholson-Weller, Katsuki Ohtani, Marcin Okrój, Luz D. Orozco, Michael K. Pangburn, Ramus Pihl, Steven D. Podos, Kenneth M. Pollard, Denise Ponard, Kristian Riesbeck, Véronique Rossi, Theresa N. Schein, Yu-Ching Su, Anna S. Świerzko, Nicole M. Thielens, Steffen Thiel, Joshua M. Thurman, Christopher B. Toomey, Menno van Lookeren Campagne, Nobutaka Wakamiya, Rick A. Wetsel, Trent M. Woodruff
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::88adbc54a7335bbb530f21b568a13a3e
https://doi.org/10.1016/b978-0-12-810420-0.01002-6
https://doi.org/10.1016/b978-0-12-810420-0.01002-6
Autor:
Kartik Manne, Kevin Macon, Sthanam V.L. Narayana, Chen Chen, Olaf Schneewind, Vengadesan Krishnan
Publikováno v:
The Journal of Biological Chemistry
Background: Esp, a secreted protease of Staphylococcus epidermidis, blocks biofilm formation of Staphylococcus aureus and its ability to colonize human nares. Results: Esp cleaves autolysin, thereby preventing the release of staphylococcal DNA as bio
Autor:
Krishnan Vengadesan, Sthanam V.L. Narayana, Tadayuki Iwase, Yoshimitsu Mizunoe, Shinya Sugumoto, Kevin Macon
Publikováno v:
Acta Crystallographica Section F Structural Biology and Crystallization Communications. 69:49-52
Esp, an extracellular serine protease from Staphylococcus epidermidis, has been shown to inhibit S. aureus biofilm formation and nasal colonization. The full-length 27 kDa pro-Esp was purified and digested with thermolysin to obtain mature Esp. The m
Publikováno v:
Journal of Molecular Biology. 414:563-577
A unique feature of the class-C-type sortases, enzymes essential for Gram-positive pilus biogenesis, is the presence of a flexible “lid” anchored in the active site. However, the mechanistic details of the “lid” displacement, suggested to be
Autor:
Prabhat Dwivedi, Arunima Mishra, Sthanam V.L. Narayana, Bharanidharan Devarajan, Hung Ton-That, Vengadesan Krishnan, John O. Cisar, Asis Das, Melissa E. Reardon
Publikováno v:
Molecular Microbiology. 81:1205-1220
By combining X-ray crystallography and modelling, we describe here the atomic structure of distinct adhesive moieties of FimA, the shaft fimbrillin of Actinomyces type 2 fimbriae, which uniquely mediates the receptor-dependent intercellular interacti