Massively parallel characterization of regulatory elements in the developing human cortex.

Autor: Deng C; Department of Bioengineering and Therapeutic Sciences, University of California, San Francisco, San Francisco, CA 94158, USA.; Institute for Human Genetics, University of California, San Francisco, San Francisco, CA 94158, USA., Whalen S; Gladstone Institutes, San Francisco, CA 94158, USA., Steyert M; Department of Anatomy, University of California, San Francisco, San Francisco, CA 94143, USA.; Department of Psychiatry, University of California, San Francisco, San Francisco, CA 94143, USA.; Department of Neurological Surgery, University of California, San Francisco, San Francisco, CA 94143, USA.; Chan Zuckerberg Biohub, San Francisco, San Francisco, CA 94158, USA.; Kavli Institute for Fundamental Neuroscience, University of California, San Francisco, CA 94143, USA.; Weill Institute for Neurosciences, University of California, San Francisco, CA 94158, USA., Ziffra R; Department of Bioengineering and Therapeutic Sciences, University of California, San Francisco, San Francisco, CA 94158, USA.; Department of Anatomy, University of California, San Francisco, San Francisco, CA 94143, USA.; Department of Psychiatry, University of California, San Francisco, San Francisco, CA 94143, USA., Przytycki PF; Gladstone Institutes, San Francisco, CA 94158, USA., Inoue F; Institute for the Advanced Study of Human Biology (WPI-ASHBi), Kyoto University, Kyoto 606-8501, Japan., Pereira DA; Department of Bioengineering and Therapeutic Sciences, University of California, San Francisco, San Francisco, CA 94158, USA.; Institute for Human Genetics, University of California, San Francisco, San Francisco, CA 94158, USA.; Graduate Program of Genetics, Institute of Biological Sciences, Federal University of Minas Gerais, Belo Horizonte, Minas Gerais 31270-901, Brazil., Capauto D; Child Study Center, Yale University, New Haven, CT 06520, USA., Norton S; Child Study Center, Yale University, New Haven, CT 06520, USA., Vaccarino FM; Child Study Center, Yale University, New Haven, CT 06520, USA.; Department of Neuroscience, Yale University, New Haven, CT 06520, USA., Pollen AA; Kavli Institute for Fundamental Neuroscience, University of California, San Francisco, CA 94143, USA.; Weill Institute for Neurosciences, University of California, San Francisco, CA 94158, USA.; Department of Neurology, University of California, San Francisco, San Francisco, CA 94143, USA.; Eli and Edythe Broad Center for Regeneration Medicine and Stem Cell Research, University of California, San Francisco, San Francisco, CA 94143, USA., Nowakowski TJ; Department of Anatomy, University of California, San Francisco, San Francisco, CA 94143, USA.; Department of Psychiatry, University of California, San Francisco, San Francisco, CA 94143, USA.; Department of Neurological Surgery, University of California, San Francisco, San Francisco, CA 94143, USA.; Kavli Institute for Fundamental Neuroscience, University of California, San Francisco, CA 94143, USA.; Weill Institute for Neurosciences, University of California, San Francisco, CA 94158, USA.; Eli and Edythe Broad Center for Regeneration Medicine and Stem Cell Research, University of California, San Francisco, San Francisco, CA 94143, USA., Ahituv N; Department of Bioengineering and Therapeutic Sciences, University of California, San Francisco, San Francisco, CA 94158, USA.; Institute for Human Genetics, University of California, San Francisco, San Francisco, CA 94158, USA., Pollard KS; Institute for Human Genetics, University of California, San Francisco, San Francisco, CA 94158, USA.; Gladstone Institutes, San Francisco, CA 94158, USA.; Chan Zuckerberg Biohub, San Francisco, San Francisco, CA 94158, USA.; Department of Epidemiology and Biostatistics, University of California, San Francisco, San Francisco, CA 94158, USA.

Publikováno v: Science (New York, N.Y.) [Science] 2024 May 24; Vol. 384 (6698), pp. eadh0559. Date of Electronic Publication: 2024 May 24.

Rapid modeling of an ultra-rare epilepsy variant in wild-type mice by in utero prime editing.

Autor: Robertson CD; Department of Pharmacology and UM-MIND, University of Maryland School of Medicine, Baltimore, MD, USA., Davis P; Department of Neurology, Boston Children's Hospital, Harvard Medical School, Boston, MA, USA., Richardson RR; Department of Pharmacology and UM-MIND, University of Maryland School of Medicine, Baltimore, MD, USA., Iffland PH 2nd; Department of Neurology, and UM-MIND, University of Maryland School of Medicine, Baltimore, MD, USA., Vieira DCO; Department of Physiology and UM-MIND, University of Maryland School of Medicine, Baltimore, MD, USA., Steyert M; Department of Pharmacology and UM-MIND, University of Maryland School of Medicine, Baltimore, MD, USA., McKeon PN; Department of Pharmacology and UM-MIND, University of Maryland School of Medicine, Baltimore, MD, USA., Romanowski AJ; Department of Pharmacology and UM-MIND, University of Maryland School of Medicine, Baltimore, MD, USA., Crutcher G; Department of Pharmacology and UM-MIND, University of Maryland School of Medicine, Baltimore, MD, USA., Jašarević E; Department of Pharmacology and UM-MIND, University of Maryland School of Medicine, Baltimore, MD, USA.; Current affiliations: MS: Department of Neurological Surgery, University of California San Francisco; EJ: Department Computational and Systems Biology, Department of Obstetrics, Gynecology and Reproductive Sciences, University of Pittsburgh School of Medicine; TB: Department of Psychiatry, University of Colorado School of Medicine., Wolff SBE; Department of Pharmacology and UM-MIND, University of Maryland School of Medicine, Baltimore, MD, USA., Mathur BN; Department of Pharmacology and UM-MIND, University of Maryland School of Medicine, Baltimore, MD, USA., Crino PB; Department of Neurology, and UM-MIND, University of Maryland School of Medicine, Baltimore, MD, USA., Bale TL; Department of Pharmacology and UM-MIND, University of Maryland School of Medicine, Baltimore, MD, USA.; Current affiliations: MS: Department of Neurological Surgery, University of California San Francisco; EJ: Department Computational and Systems Biology, Department of Obstetrics, Gynecology and Reproductive Sciences, University of Pittsburgh School of Medicine; TB: Department of Psychiatry, University of Colorado School of Medicine., Dick IE; Department of Physiology and UM-MIND, University of Maryland School of Medicine, Baltimore, MD, USA., Poulopoulos A; Department of Pharmacology and UM-MIND, University of Maryland School of Medicine, Baltimore, MD, USA.

Publikováno v: BioRxiv : the preprint server for biology [bioRxiv] 2023 Dec 19. Date of Electronic Publication: 2023 Dec 19.

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Dorsal horn CGRP-expressing interneurons contribute to nerve injury-induced mechanical hypersensitivity

Autor: Hamel K, Julia Kuhn, Etlin A, Ida J. Llewellyn-Smith, Allan I. Basbaum, Steyert M, Braz J, Bernstein M, Löken L

Primary sensory neurons are generally considered the only source of dorsal horn calcitonin gene-related peptide (CGRP), a neuropeptide critical to the transmission of pain messages. Using a tamoxifen-inducible CGRPCreER transgenic mouse, here we iden

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::da0e1c0394962d6e2b1dc49d7925a182
https://doi.org/10.1101/2020.06.08.131839

In preprints: new insights into truncated radial glia.

Autor: Steyert M, Nowakowski TJ

Publikováno v: Development (Cambridge, England) [Development] 2022 Nov 15; Vol. 149 (22). Date of Electronic Publication: 2022 Nov 16.