Zobrazeno 1 - 10
of 470
pro vyhledávání: '"Stewart T Cole"'
Autor:
Anja Furtwängler, Judith Neukamm, Lisa Böhme, Ella Reiter, Melanie Vollstedt, Natasha Arora, Pushpendra Singh, Stewart T Cole, Sascha Knauf, Sébastien Calvignac-Spencer, Ben Krause-Kyora, Johannes Krause, Verena J Schuenemann, Alexander Herbig
Publikováno v:
BioTechniques, Vol 69, Iss 6, Pp 455-459 (2020)
In ancient DNA research, the degraded nature of the samples generally results in poor yields of highly fragmented DNA; targeted DNA enrichment is thus required to maximize research outcomes. The three commonly used methods – array-based hybridizati
Externí odkaz:
https://doaj.org/article/cef51d7eea3b490489a68c4c6d5fd0f5
Autor:
Fernanda Saloum de Neves Manta, Thiago Jacomasso, Rita de Cássia Pontello Rampazzo, Suelen Justo Maria Moreira, Najua M Zahra, Stewart T Cole, Charlotte Avanzi, Thyago Leal-Calvo, Sidra Ezidio Gonçalves Vasconcellos, Phillip Suffys, Marcelo Ribeiro-Alves, Marco Aurelio Krieger, Alexandre Dias Tavares Costa, Milton Ozório Moraes
Publikováno v:
PLoS Neglected Tropical Diseases, Vol 16, Iss 2, p e0009850 (2022)
Leprosy is a chronic dermato-neurological disease caused by Mycobacterium leprae, an obligate intracellular bacterium. Timely detection is a challenge in leprosy diagnosis, relying on clinical examination and trained health professionals. Furthermore
Externí odkaz:
https://doaj.org/article/9eb1604e210244ddab1884dd60d1b4c4
Autor:
Andréanne Lupien, Caroline Shi-Yan Foo, Svetlana Savina, Anthony Vocat, Jérémie Piton, Natalia Monakhova, Andrej Benjak, Dirk A Lamprecht, Adrie J C Steyn, Kevin Pethe, Vadim A Makarov, Stewart T Cole
Publikováno v:
PLoS Pathogens, Vol 16, Iss 1, p e1008270 (2020)
The emergence of multi-drug (MDR-TB) and extensively-drug resistant tuberculosis (XDR-TB) is a major threat to the global management of tuberculosis (TB) worldwide. New chemical entities are of need to treat drug-resistant TB. In this study, the mode
Externí odkaz:
https://doaj.org/article/b7f8b7461a4442bc8a002d6f37ec16b1
Autor:
Claudia Sala, Andrej Benjak, Delia Goletti, Sayera Banu, Jesica Mazza-Stadler, Katia Jaton, Philippe Busso, Sille Remm, Marion Leleu, Jacques Rougemont, Fabrizio Palmieri, Gilda Cuzzi, Ornella Butera, Valentina Vanini, Senjuti Kabir, S M Mazidur Rahman, Laurent Nicod, Stewart T Cole
Publikováno v:
PLoS ONE, Vol 15, Iss 10, p e0240250 (2020)
The impact of tuberculosis and of anti-tuberculosis therapy on composition and modification of human lung microbiota has been the object of several investigations. However, no clear outcome has been presented so far and the relationship between M. tu
Externí odkaz:
https://doaj.org/article/b8f8745ccd7c497c9b50097ad1c20d6c
Autor:
Dany Spaggiari, Vincent Desfontaine, Sandra Cruchon, Sylvie Guinchard, Anthony Vocat, Emilyne Blattes, Jeff Pitteloud, Lorenzo Ciullini, Carine Bardinet, Anton Ivanyuk, Vadim Makarov, Olga Ryabova, Thierry Buclin, Stewart T Cole, Laurent A Decosterd
Publikováno v:
PLoS ONE, Vol 14, Iss 5, p e0217139 (2019)
The emergence of Mycobacterium tuberculosis strains resistant to current first-line antibiotic regimens constitutes a major global health threat. New treatments against multidrug-resistant tuberculosis (MDR-TB) are thus eagerly needed in particular i
Externí odkaz:
https://doaj.org/article/1873d5b37dd64dd2b9b2918092b5e503
Autor:
Claudia Sala, Nina T Odermatt, Paloma Soler-Arnedo, Muhammet F Gülen, Sofia von Schultz, Andrej Benjak, Stewart T Cole
Publikováno v:
PLoS Pathogens, Vol 14, Iss 12, p e1007491 (2018)
The ESX-1, type VII, secretion system represents the major virulence determinant of Mycobacterium tuberculosis, one of the most successful intracellular pathogens. Here, by combining genetic and high-throughput approaches, we show that EspL, a protei
Externí odkaz:
https://doaj.org/article/06f809a536ae4b8f9028346a204f13bf
Autor:
Selfu Girma, Charlotte Avanzi, Kidist Bobosha, Kassu Desta, Munir H Idriss, Philippe Busso, Yohannes Tsegaye, Shimelis Nigusse, Tsegaye Hailu, Stewart T Cole, Abraham Aseffa
Publikováno v:
PLoS Neglected Tropical Diseases, Vol 12, Iss 9, p e0006706 (2018)
BACKGROUND:Diagnosis of leprosy mainly relies on clinical examination due to the inconsistent sensitivity and poor reproducibility of the current laboratory tests. Utilisation of alternative methods to the standard Ziehl Neelsen (ZN), Fite-Faraco (FF
Externí odkaz:
https://doaj.org/article/b72c074894434fb0a8c135cdc7e4cf94
Autor:
Moises B da Silva, Juliana M Portela, Wei Li, Mary Jackson, Mercedes Gonzalez-Juarrero, Andrea Sánchez Hidalgo, John T Belisle, Raquel C Bouth, Angélica R Gobbo, Josafá G Barreto, Antonio H H Minervino, Stewart T Cole, Charlotte Avanzi, Philippe Busso, Marco A C Frade, Annemieke Geluk, Claudio G Salgado, John S Spencer
Publikováno v:
PLoS Neglected Tropical Diseases, Vol 12, Iss 6, p e0006532 (2018)
Mycobacterium leprae (M. leprae) is a human pathogen and the causative agent for leprosy, a chronic disease characterized by lesions of the skin and peripheral nerve damage. Zoonotic transmission of M. leprae to humans by nine-banded armadillos (Dasy
Externí odkaz:
https://doaj.org/article/870e3f1f0a95472baa398d3a1439a223
Autor:
Verena J Schuenemann, Charlotte Avanzi, Ben Krause-Kyora, Alexander Seitz, Alexander Herbig, Sarah Inskip, Marion Bonazzi, Ella Reiter, Christian Urban, Dorthe Dangvard Pedersen, G Michael Taylor, Pushpendra Singh, Graham R Stewart, Petr Velemínský, Jakub Likovsky, Antónia Marcsik, Erika Molnár, György Pálfi, Valentina Mariotti, Alessandro Riga, M Giovanna Belcastro, Jesper L Boldsen, Almut Nebel, Simon Mays, Helen D Donoghue, Sonia Zakrzewski, Andrej Benjak, Kay Nieselt, Stewart T Cole, Johannes Krause
Publikováno v:
PLoS Pathogens, Vol 14, Iss 5, p e1006997 (2018)
Studying ancient DNA allows us to retrace the evolutionary history of human pathogens, such as Mycobacterium leprae, the main causative agent of leprosy. Leprosy is one of the oldest recorded and most stigmatizing diseases in human history. The disea
Externí odkaz:
https://doaj.org/article/1d2b1eeff903483cbb6c16855a091083
Autor:
Mariane M A Stefani, Charlotte Avanzi, Samira Bührer-Sékula, Andrej Benjak, Chloé Loiseau, Pushpendra Singh, Maria A A Pontes, Heitor S Gonçalves, Emerith M Hungria, Philippe Busso, Jérémie Piton, Maria I S Silveira, Rossilene Cruz, Antônio Schetinni, Maurício B Costa, Marcos C L Virmond, Suzana M Diorio, Ida M F Dias-Baptista, Patricia S Rosa, Masanori Matsuoka, Maria L F Penna, Stewart T Cole, Gerson O Penna
Publikováno v:
PLoS Neglected Tropical Diseases, Vol 11, Iss 6, p e0005598 (2017)
Since leprosy is both treated and controlled by multidrug therapy (MDT) it is important to monitor recurrent cases for drug resistance and to distinguish between relapse and reinfection as a means of assessing therapeutic efficacy. All three objectiv
Externí odkaz:
https://doaj.org/article/91540a58ac934e209d0d7e74859d55f7