Zobrazeno 1 - 10
of 37
pro vyhledávání: '"Stewart M. Knoepp"'
Autor:
Yuhuan Xie, Krishna M. Ella, Terra C. Gibbs, Marianne E. Yohannan, Stewart M. Knoepp, Pravita Balijepalli, G. Patrick Meier, Kathryn E. Meier
Publikováno v:
Cells, Vol 13, Iss 6, p 520 (2024)
Lysophosphatidic acid (LPA) is a lipid mediator that binds to G-protein-coupled receptors, eliciting a wide variety of responses in mammalian cells. Lyso-phospholipids generated via phospholipase A2 (PLA2) can be converted to LPA by a lysophospholipa
Externí odkaz:
https://doaj.org/article/7d4978fdcd01418ab0d3880c7c45722f
Publikováno v:
Journal of Lower Genital Tract Disease. 18:291-297
Objective The Hybrid Capture II high-risk HPV test (HC II hrHPVT) improves early detection of cervical neoplasia in Pap tests. However, weakly positive HC II results may be reported as indeterminate or "equivocal," for which there is little clinical
Publikováno v:
Cancer Cytopathology. 121:489-499
BACKGROUND Rearrangements involving the anaplastic lymphoma kinase (ALK) gene are present in approximately 5% of lung adenocarcinomas. Crizotinib is approved for the treatment of lung adenocarcinomas harboring ALK rearrangements. Patients with advanc
Autor:
Bryan L. Betz, Michael H. Roh, Christopher D. Lao, Stewart M. Knoepp, Bruce G. Redman, Helmut C. Weigelin, Kurt D. Bernacki
Publikováno v:
American Journal of Clinical Pathology. 138:670-677
Patients with advanced-stage melanoma harboring a BRAF mutation are candidates for BRAF inhibition as a therapeutic strategy. The use of fine-needle aspiration (FNA) to diagnose metastatic melanoma is increasing. Studies examining the predictive valu
Autor:
Michael H. Roh, Stewart M. Knoepp
Publikováno v:
Cancer Cytopathology. 121:120-128
Numerous cytologic techniques aimed at effectively acquiring patient material for molecular testing have been proposed. Such techniques are becoming ever more important in an age of personalized medicine. In this commentary, the authors explored some
Publikováno v:
Diagnostic Cytopathology. 41:425-430
Metastatic malignancy represents a common cause of effusions. Immunocytochemistry (ICC) is useful in confirming malignancy and gaining insight into the site of origin. Cell blocks are commonly utilized for this purpose; nonetheless, when the malignan
Publikováno v:
Diagnostic Cytopathology. 41:729-733
Merkel cell carcinoma represents a highly aggressive cutaneous malignancy characterized by regional recurrences, lymph node metastases, distant metastases, and high mortality. As the cytomorphology of Merkel cell carcinoma can be mimicked by other ma
Publikováno v:
Genes, Chromosomes and Cancer. 51:283-289
Familial adenomatous polyposis (FAP) is an autosomal dominant cancer predisposition syndrome that accounts for approximately 0.5–1% of all colorectal cancer cases. It is caused by germline mutations in the gene encoding the adenomatous polyposis co
Autor:
Claire W. Michael, Michael H. Roh, Rodolfo Rasche, Robertson Davenport, Jeremiah Placido, Stewart M. Knoepp, Xin Jing, Kim Hookim
Publikováno v:
Diagnostic Cytopathology. 40:1037-1042
We conducted a group consensus review of thyroid aspirates that were previously interpreted as “atypia of undetermined significance/follicular lesion of undetermined significance” (AUS/FLUS) and followed by surgical interventions. The study aimed
Autor:
Heather M. Sansbury, Stewart M. Knoepp, Manpreet S. Chahal, Hsun Ku, Zhihong Zhang, Kathryn E. Meier, Stephen Tomlinson, Yuhuan Xie
Publikováno v:
Clinical & Experimental Metastasis. 28:551-565
The murine EL4 lymphoma cell line exists in variants that are either sensitive or resistant to phorbol 12-myristate 13-acetate (PMA). In sensitive cells, PMA causes Erk MAPK activation and Erk-mediated growth arrest. In resistant cells, PMA induces a