Výsledky vyhledávání - "Stewart M. Holt"

Comparison of 2 Formaldehyde Exposure Assessment Devices in a Physical Therapy Education Program Anatomy Laboratory

Autor: Colin McGowan, Kathy Starr, Christina Ridenour, Gary Tencer, Janet M. Cope, Stewart M. Holt

Publikováno v: Journal of Physical Therapy Education. 28:15-20

INTRODUCTIONWhile formaldehyde (FA) has a long history as a preferred fixative in the preservation of human donors for medical education,1 it is also a known carcinogen.2,3 It is a harmful chemical that has been implicated in a number of cancers, as

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::05653fa00a216b157226b195a6cde06c
https://doi.org/10.1097/00001416-201407000-00003

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Comparison of Personal Formaldehyde Levels in Anatomy Laboratories of 5 Physical Therapist Education Programs

Autor: Davis Templeton, Jackson K. Thomas, Janet M. Cope, Edward Kernick, Kathy Pappas, Erin Sanders, Stewart M. Holt, Laura Corriher, Kathy Starr

Publikováno v: Journal of Physical Therapy Education. 25:21-30

Background and Purpose.The current trend in anatomy education requires medical students to spend fewer hours with human donors, while physical therapist (PT) students are spending an increasing amount of time working in the human anatomy laboratory.

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::9817657337ccf1ad9a04e0c7aab53d95
https://doi.org/10.1097/00001416-201107000-00006

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Detection of Complex DNA Damage in γ-Irradiated Acute Lymphoblastic Leukemia Pre-B NALM-6 Cells

Autor: Alexandros G. Georgakilas, Stewart M. Holt

Publikováno v: Radiation Research. 168:527-534

Bistranded complex DNA damage, i.e., double-strand breaks (DSBs) and non-DSB oxidative clustered DNA lesions, is hypothesized to challenge the repair mechanisms of the cell and consequently the genomic integrity. The oxidative clustered DNA lesions m

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::41b949edc33fafffced098b0f9ede021
https://doi.org/10.1667/rr0974.1

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Measurement of oxidatively-induced clustered DNA lesions using a novel adaptation of single cell gel electrophoresis (comet assay)

Autor: Stewart M. Holt, Jessica M. Hair, Alexandros G. Georgakilas, Charles W. Loftin

Publikováno v: Current Protocols in Cell Biology

The two basic groups of complex DNA damage are double-strand breaks (DSBs) and non-DSB oxidatively-induced clustered DNA lesions (OCDLs). The single-cell gel electrophoresis (SCGE) or comet assay has been widely used for the detection of low levels o

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::66f89b9be979795a45b302f069360883
https://pubmed.ncbi.nlm.nih.gov/21154553

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Anatomy laboratory instruction and occupational exposure to formaldehyde

Autor: Janet M. Cope, Maria C. Mirabelli, Stewart M. Holt

Publikováno v: Occupational and environmental medicine. 68(5)

Human donors used in dental, allopathic and osteopathic medical, physical therapy, veterinary and other healthcare-related education programs are preserved using formalin, an aqueous solution of 37% (w/v) formaldehyde (CH2O, CAS no. 50-00-0). During

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::01ae297e0527a7aa5ead77206615c292
https://pubmed.ncbi.nlm.nih.gov/21097949

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Comparison of personal formaldehyde levels in the anatomy laboratories of five physical therapy education programs

Autor: Erin Sanders, K. Jackson Thomas, Janet M. Cope, Kathy Pappas, Davis Templeton, Stewart M. Holt, Edward Kernick, Laura Corriher

Publikováno v: The FASEB Journal. 23

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::cc6582bed98080cfb3df37ddde175867
https://doi.org/10.1096/fasebj.23.1_supplement.lb1

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Compromised repair of clustered DNA damage in the human acute lymphoblastic leukemia MSH2-deficient NALM-6 cells

Autor: Alexandros G. Georgakilas, Stewart M. Holt, Mihalis I. Panayiotidis, Jean-Luc Scemama

Publikováno v: Mutation research. 674(1-2)

Ionizing radiation (IR) induces two classes of complex DNA damage, double-strand breaks (DSBs) and non-DSB bi-stranded oxidative clustered DNA lesions (OCDLs). OCDLs may consist of single strand breaks (SSBs), oxidized purines/pyrimidines and abasic

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f96e02fee49fee96a8dc414d9a432ced
https://pubmed.ncbi.nlm.nih.gov/18955159

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Osmotic effects on arginine kinase function in living muscle of the blue crab Callinectes sapidus

Autor: Stewart M. Holt, Stephen T. Kinsey

Publikováno v: The Journal of experimental biology. 205(Pt 12)

SUMMARY Flux was examined through the reaction catalyzed by arginine kinase in intact blue crab (Callinectes sapidus) muscle during simulated changes in salinity. Isolated dark levator muscles from the swimming leg were superfused with a saline solut

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::55d12cea7cfd617894b678053d11101f
https://pubmed.ncbi.nlm.nih.gov/12042336

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