Zobrazeno 1 - 10
of 29
pro vyhledávání: '"Stewart Heitmann"'
Publikováno v:
eLife, Vol 12 (2023)
Many classes of drugs can induce fatal cardiac arrhythmias by disrupting the electrophysiology of cardiomyocytes. Safety guidelines thus require all new drugs to be assessed for pro-arrhythmic risk prior to conducting human trials. The standard safet
Externí odkaz:
https://doaj.org/article/164b1428954745ecb5d100dfce18f458
Publikováno v:
PLoS Computational Biology, Vol 17, Iss 2, p e1008683 (2021)
Contemporary accounts of the initiation of cardiac arrhythmias typically rely on after-depolarizations as the trigger for reentrant activity. The after-depolarizations are usually triggered by calcium entry or spontaneous release within the cells of
Externí odkaz:
https://doaj.org/article/a9814cf5d73546f88b4a219c7141766b
Autor:
Stewart Heitmann, G Bard Ermentrout
Publikováno v:
PLoS Computational Biology, Vol 16, Iss 9, p e1008164 (2020)
The majority of neurons in primary visual cortex respond selectively to bars of light that have a specific orientation and move in a specific direction. The spatial and temporal responses of such neurons are non-separable. How neurons accomplish that
Externí odkaz:
https://doaj.org/article/8ffc7118112649dc9e560dcafe049887
Autor:
Stewart Heitmann, Michael Breakspear
Publikováno v:
Network Neuroscience, Vol 02, Iss 02, Pp 150-174 (2018)
The study of fluctuations in time-resolved functional connectivity is a topic of substantial current interest. As the term “dynamic functional connectivity” implies, such fluctuations are believed to arise from dynamics in the neuronal systems ge
Externí odkaz:
https://doaj.org/article/92bb60ff84f44069896e2ae51a27d7ef
Publikováno v:
PLoS Computational Biology, Vol 13, Iss 1, p e1005349 (2017)
Constant optogenetic stimulation targeting both pyramidal cells and inhibitory interneurons has recently been shown to elicit propagating waves of gamma-band (40-80 Hz) oscillations in the local field potential of non-human primate motor cortex. The
Externí odkaz:
https://doaj.org/article/1fbcc820f85446e6be60a392a91e154f
Autor:
Joel Pearson, Rocco Chiou, Sebastian Rogers, Marcus Wicken, Stewart Heitmann, Bard Ermentrout
Publikováno v:
eLife, Vol 5 (2016)
Hallucinations occur in both normal and clinical populations. Due to their unpredictability and complexity, the mechanisms underlying hallucinations remain largely untested. Here we show that visual hallucinations can be induced in the normal populat
Externí odkaz:
https://doaj.org/article/8f1df9a6d0ca4cc6bed53a6b876d0d28
Publikováno v:
PLoS Computational Biology, Vol 9, Iss 10, p e1003260 (2013)
Traveling waves of neuronal oscillations have been observed in many cortical regions, including the motor and sensory cortex. Such waves are often modulated in a task-dependent fashion although their precise functional role remains a matter of debate
Externí odkaz:
https://doaj.org/article/340a4e30de8c44628c7543b449ec928d
Publikováno v:
Frontiers in Human Neuroscience, Vol 4 (2010)
Understanding the fundamental mechanisms governing fluctuating oscilla- tions in large-scale cortical circuits is a crucial prelude to a proper knowl- edge of their role in both adaptive and pathological cortical processes. Neu- roscience research in
Externí odkaz:
https://doaj.org/article/2b119db41b904600ad910b9d681a487e
Autor:
Rocio K. Finol-Urdaneta, Rebekah Ziegman, Zoltan Dekan, Jeffrey R. McArthur, Stewart Heitmann, Karen Luna-Ramirez, Han-Shen Tae, Alexander Mueller, Hana Starobova, Yanni K.-Y. Chin, Joshua S. Wingerd, Eivind A. B. Undheim, Ben Cristofori-Armstrong, Adam P. Hill, Volker Herzig, Glenn F. King, Irina Vetter, Lachlan D. Rash, David J. Adams, Paul F. Alewood
Publikováno v:
Proceedings of the National Academy of Sciences of the United States of America
Significance Pain development and discomfort are universal features of spider envenomation, yet severe pain arising from bites by Old World spiders is poorly understood. Molecular analyses of the venom of the King Baboon spider revealed abundant expr
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::00b39880bcca9700b1b3fe917c377bea
https://hdl.handle.net/11250/3058935
https://hdl.handle.net/11250/3058935