Zobrazeno 1 - 10
of 76
pro vyhledávání: '"Stewart Gilmour"'
Publikováno v:
PLoS ONE, Vol 4, Iss 9, p e7271 (2009)
A link has been established between prenatal nutrition and the development of metabolic and cardiovascular diseases later in life, a process referred to as developmental programming. It has been suggested that the trajectory of development is shifted
Externí odkaz:
https://doaj.org/article/9142e044450b446d8fb6201fd4e2040e
Autor:
Chris De Savi, Glen Andrews, Anthony Ronald Cook, Rhona J. Cox, Peter Stewart Gilmour, Simon Young, Daniel J. Warner, Beth Parker, Dickinson Mark, Amy McDonough, Matthew Dearman, Louis C. Morrill, Rob Riley
Publikováno v:
Journal of Medicinal Chemistry. 57:4661-4676
Oral phosphodiesterase 4 (PDE4) inhibitors, such as cilomilast and roflumilast, have been shown to be efficacious against chronic obstructive pulmonary disease (COPD). However, these drugs have been hampered by mechanism-related side effects such as
Publikováno v:
International Journal of Drug Policy. 16:300-307
Objective: To examine whether a reduction in the availability of heroin in New South Wales (NSW) in 2001 was associated with community level changes in heroin and other drug use. Method: Data from the NSW Alcohol and Drug Information Service (ADIS) o
Autor:
Murray D. Mitchell, Timothy A. Sato, Elicia B.E Berry, Rachel J. A. Helliwell, R. Stewart Gilmour
Publikováno v:
Prostaglandins, Leukotrienes and Essential Fatty Acids. 71:191-197
Cyclopentenone prostaglandins, Delta(12)-PGJ(2) and 15d-PGJ(2), have potent anti-tumour and anti-inflammatory activities, and have been shown to induce apoptosis in amnion-derived WISH cells. In this study, we have investigated the protective effects
Publikováno v:
Oncogene. 23:524-534
Rhabdomyosarcoma (RMS) tumors are the most common soft-tissue sarcomas in childhood. In this investigation, we show that myostatin, a skeletal muscle-specific inhibitor of growth and differentiation is expressed and translated in the cultured RMS cel
Autor:
R. Stewart Gilmour, K.W. Marvin, Elicia B.E Berry, R.L. Eykholt, Murray D. Mitchell, Rachel J. A. Helliwell
Publikováno v:
Molecular Pharmacology. 64:1586-1590
Peroxisome proliferator-activated receptors (PPARs) are a family of nuclear receptors that are involved in lipid metabolism, differentiation, proliferation, cell death, and inflammation. Three subtypes have been identified: PPAR-alpha, -delta, and -g
Publikováno v:
Advances in Enzyme Regulation. 43:1-13
Publikováno v:
Journal of Biological Chemistry. 277:49831-49840
Myostatin, a negative regulator of myogenesis, is shown to function by controlling the proliferation of myoblasts. In this study we show that myostatin is an inhibitor of myoblast differentiation and that this inhibition is mediated through Smad 3. I
Autor:
Irene Faenza, Pann-Ghill Suh, Alberto M. Martelli, R. Stewart Gilmour, Lucio Cocco, Alberto Bavelloni, Sandra Marmiroli, Alessandro Matteucci, Lucia Manzoli
Publikováno v:
Biochimica et Biophysica Acta (BBA) - Molecular Cell Research. 1589:305-310
It is well established that phospholipase C (PLC) h1 plays a role in the nuclear compartment and is involved in the signalling pathway that controls the switching of the erythroleukemia cells programming from an undifferentiated to a differentiated s
Autor:
Francesco A. Manzoli, R. Stewart Gilmour, O. Barnabei, Lucio Cocco, Mirella Falconi, Alberto M. Martelli, Marco Vitale
Publikováno v:
Advances in Enzyme Regulation. 42:181-193