Zobrazeno 1 - 10
of 11
pro vyhledávání: '"Stewart D. Chipman"'
Autor:
Thomas Tüting, Milley Robert J, Robert L. Coffman, Edwina Naik, Stewart D. Chipman, Cristiana Guiducci, Chi Ying, Carlo Calacsan
Publikováno v:
Cancer Research. 77:5596-5596
Therapeutic success of a cancer vaccine requires substantial expansion of vaccine-primed CTL and efficient differentiation to polyfunctional T cells capable of migrating from the site of vaccination to metastatic sites. We have evaluated the tumor it
Autor:
Elizabeth M. Burke, Jay R. Shapiro, David B. Danner, James A. Coderre, John L. Stock, Stewart D. Chipman
Publikováno v:
Journal of Cellular Physiology. 150:517-525
The opossum kidney (OK) cell was used as a model to test the hypothesis that estrogen directly affects proximal renal tubular epithelial cells. To demonstrate the expression of estrogen receptor in OK cells, we developed an approach using reverse tra
Autor:
Stewart D. Chipman, Hope O. Sweet, Muriel T. Davisson, David W. Rowe, Richard J. Wenstrup, Jay R. Shapiro, Sandy C. Marks, Alan R. Shuldiner, Daniel J. McBride
Publikováno v:
Proceedings of the National Academy of Sciences of the United States of America. 90(5)
Osteogenesis imperfecta (OI) is a heritable disorder of connective tissue associated with fractures, osteopenia, and short stature. OI results from mutations affecting the pro alpha 1 or pro alpha 2 gene of type I collagen. We describe a strain of mi
Autor:
Monique B. McKinstry, Philip Branson, Stewart D. Chipman, David W. Rowe, Mary Louise Stover, Jay R. Shapiro
Publikováno v:
Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research. 7(7)
This study compares the synthesis of mutant type I collagen in cultured dermal fibroblasts and trabecular osteoblasts that were isolated from a patient with moderately severe osteogenesis imperfecta (type IV). Previous study of this patient's dermal
Publikováno v:
Experimental Cell Research. 118:410-414
A critical nutrient for the growth of SV3T3 cells is iron. Iron must be added in the ferrous form or, if in the ferric state, with a suitable complexing agent. Both transferrin and hemoglobin, as iron complexes, will stimulate cell growth in biotin s
Autor:
Leesa M. Barone, Carl Franzblau, Barbara Faris, Paul Toselli, Stewart D. Chipman, Barry W. Oakes
Publikováno v:
Biochimica et Biophysica Acta (BBA) - General Subjects. 840:245-254
The protein composition in the extracellular matrix of cultured neonatal rat aortic smooth muscle cells has been monitored over time in culture. The influence of ascorbate on insoluble elastin and collagen has been described. In the absence of ascorb
Publikováno v:
Journal of Biological Chemistry. 260:12780-12785
The synthesis and extracellular deposition of elastin by cultured neonatal rat aorta smooth muscle cells has been followed. The addition of beta-aminopropionitrile to the culture medium promotes accumulation of soluble precursors of elastin. Under su
Publikováno v:
Connective tissue research. 21(1-4)
A positive family history is considered a risk factor for osteoporosis (OP) although the genetic or biochemical basis for this relationship remains undefined. Various mutations affecting normal synthesis of type I collagen have been reported in osteo
Publikováno v:
Developmental biology. 122(1)
This report documents osteoblast differentiation in vitro, as demonstrated by the 50–100× increase of proteins which are known markers of the osteoblast phenotype. Collagen type I and osteocalcin synthesis and accumulation, alkaline phosphatase ac
Publikováno v:
FEBS letters. 111(1)