Zobrazeno 1 - 10
of 363
pro vyhledávání: '"Stewart A. Factor"'
Autor:
Samuel Frank, Karen E. Anderson, Hubert H. Fernandez, Robert A. Hauser, Daniel O. Claassen, David Stamler, Stewart A. Factor, Joohi Jimenez-Shahed, Hadas Barkay, Amanda Wilhelm, Jessica K. Alexander, Nayla Chaijale, Steve Barash, Juha-Matti Savola, Mark Forrest Gordon, Maria Chen
Publikováno v:
Neurology and Therapy, Vol 13, Iss 3, Pp 655-675 (2024)
Abstract Introduction Deutetrabenazine is a vesicular monoamine transporter 2 inhibitor used to treat tardive dyskinesia (TD) and chorea associated with Huntington disease (HD). To enhance detection of safety signals across individual trials, integra
Externí odkaz:
https://doaj.org/article/86f74f75204d4fddb3bf5d6367615519
Autor:
Mark Saad, Sofia Hefner, Suzann Donovan, Doug Bernhard, Richa Tripathi, Stewart A. Factor, Jeanne M. Powell, Hyeokhyen Kwon, Reza Sameni, Christine D. Esper, J. Lucas McKay
Publikováno v:
Sensors, Vol 24, Iss 15, p 4960 (2024)
Tremor, defined as an “involuntary, rhythmic, oscillatory movement of a body part”, is a key feature of many neurological conditions including Parkinson’s disease and essential tremor. Clinical assessment continues to be performed by visual obs
Externí odkaz:
https://doaj.org/article/d021113c2a614bd08af53c6715e1db06
Autor:
J. Lucas McKay, Jonathan Nye, Felicia C. Goldstein, Barbara Sommerfeld, Yoland Smith, David Weinshenker, Stewart A. Factor
Publikováno v:
Neurobiology of Disease, Vol 179, Iss , Pp 106048- (2023)
Background: Freezing of gait (FOG) is a major cause of falling in Parkinson's disease (PD) and can be responsive or unresponsive to levodopa. Pathophysiology is poorly understood. Objective: To examine the link between noradrenergic systems, the deve
Externí odkaz:
https://doaj.org/article/1be36660667442c3ab69268f36d48aeb
Autor:
N. Jabin Gong, Gari D. Clifford, Christine D. Esper, Stewart A. Factor, J. Lucas McKay, Hyeokhyen Kwon
Publikováno v:
Sensors, Vol 23, Iss 19, p 8330 (2023)
Characterizing motor subtypes of Parkinson’s disease (PD) is an important aspect of clinical care that is useful for prognosis and medical management. Although all PD cases involve the loss of dopaminergic neurons in the brain, individual cases may
Externí odkaz:
https://doaj.org/article/411f73b235db4caf9116ad168756f74f
Autor:
Zachary D. Wallen, William J. Stone, Stewart A. Factor, Eric Molho, Cyrus P. Zabetian, David G. Standaert, Haydeh Payami
Publikováno v:
npj Parkinson's Disease, Vol 7, Iss 1, Pp 1-11 (2021)
Abstract The causes of complex diseases remain an enigma despite decades of epidemiologic research on environmental risks and genome-wide studies that have uncovered tens or hundreds of susceptibility loci for each disease. We hypothesize that the mi
Externí odkaz:
https://doaj.org/article/3c0a6ff80f1c4756b10bac34c75cba2d
Autor:
Hyeokhyen Kwon, Gari D. Clifford, Imari Genias, Doug Bernhard, Christine D. Esper, Stewart A. Factor, J. Lucas McKay
Publikováno v:
Sensors, Vol 23, Iss 4, p 1766 (2023)
Freezing of gait (FOG) is a poorly understood heterogeneous gait disorder seen in patients with parkinsonism which contributes to significant morbidity and social isolation. FOG is currently measured with scales that are typically performed by moveme
Externí odkaz:
https://doaj.org/article/fbc56730aef44d1b903a0db13eefd447
Autor:
Robert A. Hauser, Hadas Barkay, Hubert H. Fernandez, Stewart A. Factor, Joohi Jimenez-Shahed, Nicholas Gross, Leslie Marinelli, Amanda Wilhelm, Jessica Alexander, Mark Forrest Gordon, Juha-Matti Savola, Karen E. Anderson
Publikováno v:
Frontiers in Neurology, Vol 13 (2022)
BackgroundDeutetrabenazine is a vesicular monoamine transporter 2 inhibitor approved for the treatment of tardive dyskinesia (TD) in adults. In two 12-week pivotal studies, deutetrabenazine demonstrated statistically significant improvements in Abnor
Externí odkaz:
https://doaj.org/article/4af985f17f784d0e908aedd4c2ecbd20
Autor:
Laura M. Scorr, Stewart A. Factor, Sahyli Perez Parra, Rachel Kaye, Randal C. Paniello, Scott A. Norris, Joel S. Perlmutter, Tobias Bäumer, Tatiana Usnich, Brian D. Berman, Marie Mailly, Emmanuel Roze, Marie Vidailhet, Joseph Jankovic, Mark S. LeDoux, Richard Barbano, Florence C. F. Chang, Victor S. C. Fung, Sarah Pirio Richardson, Andrew Blitzer, H. A. Jinnah
Publikováno v:
Frontiers in Neurology, Vol 12 (2021)
Objective: The goal of this study is to better characterize the phenotypic heterogeneity of oromandibular dystonia (OMD) for the purpose of facilitating early diagnosis.Methods: First, we provide a comprehensive summary of the literature encompassing
Externí odkaz:
https://doaj.org/article/0634a2ad37b94f16a06e33a9b223c951
Autor:
Megan E. Wadon, Grace A. Bailey, Zehra Yilmaz, Emily Hubbard, Meshari AlSaeed, Amy Robinson, Duncan McLauchlan, Richard L. Barbano, Laura Marsh, Stewart A. Factor, Susan H. Fox, Charles H. Adler, Ramon L. Rodriguez, Cynthia L. Comella, Stephen G. Reich, William L. Severt, Christopher G. Goetz, Joel S. Perlmutter, Hyder A. Jinnah, Katharine E. Harding, Cynthia Sandor, Kathryn J. Peall
Publikováno v:
Brain and Behavior, Vol 11, Iss 8, Pp n/a-n/a (2021)
Abstract Background: Non‐motor symptoms are well established phenotypic components of adult‐onset idiopathic, isolated, focal cervical dystonia (AOIFCD). However, improved understanding of their clinical heterogeneity is needed to better target t
Externí odkaz:
https://doaj.org/article/d319ab97d6344ddf9b097d56ff0ee105
Publikováno v:
Frontiers in Human Neuroscience, Vol 14 (2020)
Leg rigidity is associated with frequent falls in people with Parkinson’s disease (PD), suggesting a potential role in functional balance and gait impairments. Changes in the neural state due to secondary tasks, e.g., activation maneuvers, can exac
Externí odkaz:
https://doaj.org/article/59fa8ad812f64dec871b9dba87c95ef1