Zobrazeno 1 - 10
of 12
pro vyhledávání: '"Stewart A. Cederholm-Williams"'
Publikováno v:
The American Journal of Cardiology. 71:640-645
Neutralization antibodies to streptokinase increase to high levels within several days of administration. It is not known how long these high levels persist. The time course of antibody levels needs to be further characterized owing to the increasing
Publikováno v:
Blood Coagulation & Fibrinolysis. 3:605-614
Plasminogen is the zymogen form of plasmin, a broad specificity serine protease whose activity contributes to a variety of normal and pathological conditions, including intravascular thrombolysis and extracellular proteolysis. Plasminogen contains se
Autor:
Stewart A. Cederholm-Williams, Keith Martyn Dawson, Chris P. Ponting, Charles S. Cockell, Julian M. Marshall
Human Glu-plasminogen adopts at least three conformations that provide a means for regulating the specificity of its activation in vivo. It has been proposed previously that the closed (α) conformation of human Glu-plasminogen is maintained through
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::71c93c2ccf60f2950fd2103130ac0878
https://europepmc.org/articles/PMC1219561/
https://europepmc.org/articles/PMC1219561/
Autor:
J. M. Marshall, W. T. Melvin, Stewart A. Cederholm-Williams, Patrick J. Gaffney, D. Thompson, T. A. Edgell, C. Stirk
Publikováno v:
Blood Coagulation & Fibrinolysis. 9:707
Autor:
N-E Holm, J. E. Fairbrother, P. A. D. E. Edwardson, R. Gardener, Stewart A. Cederholm-Williams, D. A. Hollingsbee
Publikováno v:
Blood Coagulation & Fibrinolysis. 9:718
Autor:
Stewart A Cederholm‐Williams
Publikováno v:
Medical Journal of Australia. 161:575-575
Autor:
Patrick J. Gaffney, kevin Burnand, M. Pattison, Stewart A. Cederholm-Williams, S. Houlbrook, M. Mahmoud, G. T. Layer
Publikováno v:
Fibrinolysis. 1:237-240
Raised levels of tissue fibrinolytic activity have been observed in certain malignant tissues and these may determine metastatic spread. We have investigated the fibrinolytic enzymes tissue plasminogen activator (tPA) and urokinase (UK) in 26 breast
Publikováno v:
Fibrinolysis. 2:107-110
Human umbilical vein endothelial cells cultured on plastic microcarrier spheres were used in an acute release model to study tissue plasminogen activator (t-PA) and von Willebrand factor (vWF). No consistent acute release of t-PA could be directly de
Publikováno v:
Fibrinolysis. 1:241-245
Vascular endothelium is very important in the control of fibrin deposition, and defects of function often lead to thrombosis. Microvascular disease and thrombosis are clinical features of systemic lupus erythematosus (SLE), and anti-phospholipid anti
Publikováno v:
European Journal of Biochemistry. 100:125-132
Streptokinase reacts very rapidly with human plasmin (rate constant 5.4 S 10(7) M-1 s-1) forming a 1:1 stoichiometric complex which has a dissociation constant of 5 X 10(-11) M. This plasmin-streptokinase complex is 10(5) times less reactive towards