Zobrazeno 1 - 10
of 343
pro vyhledávání: '"Stewart A. Anderson"'
Autor:
Youtao Lu, Jaehee Lee, Jifen Li, Srinivasa Rao Allu, Jinhui Wang, HyunBum Kim, Kevin L. Bullaughey, Stephen A. Fisher, C. Erik Nordgren, Jean G. Rosario, Stewart A. Anderson, Alexandra V. Ulyanova, Steven Brem, H. Isaac Chen, John A. Wolf, M. Sean Grady, Sergei A. Vinogradov, Junhyong Kim, James Eberwine
Publikováno v:
Nature Communications, Vol 14, Iss 1, Pp 1-19 (2023)
Abstract Genomic DNA (gDNA) undergoes structural interconversion between single- and double-stranded states during transcription, DNA repair and replication, which is critical for cellular homeostasis. We describe “CHEX-seq” which identifies the
Externí odkaz:
https://doaj.org/article/2d577bcc2fbc42bdb820b2ed40c2f17f
Publikováno v:
STAR Protocols, Vol 1, Iss 3, Pp 100190- (2020)
Summary: This protocol establishes a tri-culture of hiPSC-derived neurons, astrocytes, and microglia for the study of cellular interactions during homeostasis, injury, and disease. This system allows for mechanistic studies that can identify the role
Externí odkaz:
https://doaj.org/article/0927d346b1b54b6d8a250dfb0f3862a5
Autor:
David J. Tischfield, Dave K. Saraswat, Andrew Furash, Stephen C. Fowler, Marc V. Fuccillo, Stewart A. Anderson
Publikováno v:
Neurobiology of Disease, Vol 103, Iss , Pp 174-183 (2017)
The zinc-finger SWIM domain-containing protein 6 (ZSWIM6) is a protein of unknown function that has been associated with schizophrenia and limited educational attainment by three independent genome-wide association studies. Additionally, a putatively
Externí odkaz:
https://doaj.org/article/de5c8e1d107f46e7ba78ed155df3f9ba
Publikováno v:
Stem Cell Reports, Vol 8, Iss 5, Pp 1135-1143 (2017)
Recent studies indicate that the location of neurogenesis within the medial ganglionic eminence (MGE) critically influences the fate determination of cortical interneuron subgroups, with parvalbumin (Pv) interneurons originating from subventricular z
Externí odkaz:
https://doaj.org/article/7ee27e73398f4d23b24bbe313fa42b33
Autor:
Erika G. Lin-Hendel, Meagan J. McManus, Douglas C. Wallace, Stewart A. Anderson, Jeffrey A. Golden
Publikováno v:
Cell Reports, Vol 15, Iss 2, Pp 229-237 (2016)
Mitochondrial dysfunction has been increasingly linked to neurodevelopmental disorders such as intellectual disability, childhood epilepsy, and autism spectrum disorder, conditions also associated with cortical GABAergic interneuron dysfunction. Alth
Externí odkaz:
https://doaj.org/article/a39b85ad2b7e4b618e60729dac293b2d
Publikováno v:
Cell Reports, Vol 13, Iss 6, Pp 1090-1095 (2015)
Fate determination in the mammalian telencephalon, with its diversity of neuronal subtypes and relevance to neuropsychiatric disease, remains a critical area of study in neuroscience. Most studies investigating this topic focus on the diversity of ne
Externí odkaz:
https://doaj.org/article/27e8060758574ed48cf84c8cd7497f41
Autor:
Deqiang Li, Norifumi Takeda, Rajan Jain, Lauren J. Manderfield, Feiyan Liu, Li Li, Stewart A. Anderson, Jonathan A. Epstein
Publikováno v:
Stem Cell Research, Vol 15, Iss 3, Pp 522-529 (2015)
In the adult dentate gyrus (DG) and in the proliferative zone lining the lateral ventricle (LV-PZ), radial glia-like (RGL) cells are neural stem cells (NSCs) that generate granule neurons. A number of molecular markers including glial fibrillary acid
Externí odkaz:
https://doaj.org/article/e2ec176484c74b1a87401b95fae491de
Autor:
Nevena V. Radonjić, Albert E. Ayoub, Fani Memi, Xiaojing Yu, Asif Maroof, Igor Jakovcevski, Stewart A. Anderson, Pasko Rakic, Nada Zecevic
Publikováno v:
Cell Reports, Vol 9, Iss 6, Pp 2139-2151 (2014)
Evolutionary elaboration of tissues starts with changes in the genome and location of the stem cells. For example, GABAergic interneurons of the mammalian neocortex are generated in the ventral telencephalon and migrate tangentially to the neocortex,
Externí odkaz:
https://doaj.org/article/f5764d258d5b4e4fb0390ff4bdade53f
Publikováno v:
Neurobiology of Disease, Vol 53, Iss , Pp 36-48 (2013)
GABAergic interneurons of the cerebral cortex (cINs) play crucial roles in many aspects of cortical function. The diverse types of cINs are classified into subgroups according to their morphology, intrinsic physiology, neurochemical markers and synap
Externí odkaz:
https://doaj.org/article/37a1cbd33a684783b95d46f020778d19
Publikováno v:
Frontiers in Cellular Neuroscience, Vol 10 (2016)
D-serine is an endogenous coagonist at the glycine site of synaptic NMDA receptors (NMDARs), synthesized by serine racemase (SR) through conversion of L-serine. It is crucial for synaptic plasticity and is implicated in schizophrenia. Our previous st
Externí odkaz:
https://doaj.org/article/9d6a82d2efbc43409202a4249904b4d2