Zobrazeno 1 - 6
of 6
pro vyhledávání: '"Stevi J. Johnson"'
Autor:
Barbara L. Wehde, Patrick D. Rädler, Hridaya Shrestha, Stevi J. Johnson, Aleata A. Triplett, Kay-Uwe Wagner
Publikováno v:
Cell Reports, Vol 25, Iss 8, Pp 2192-2207.e5 (2018)
Summary: Janus kinases (JAKs) and their downstream STAT proteins play key roles in cytokine signaling, tissue homeostasis, and cancer development. Using a breast cancer model that conditionally lacks Janus kinase 1, we show here that JAK1 is essentia
Externí odkaz:
https://doaj.org/article/a77e352af1744e28aa6aa1b7d2d7faf8
Autor:
Paul S. MacLean, Ann D. Thor, Michael C. Rudolph, Stevi J. Johnson, Anthony D. Elias, Andrew J. Dannenberg, Heather M. Brechbuhl, Peter Kabos, Elizabeth A. Wellberg, Xi Kathy Zhou, Domenick J. Falcone, Omar El-Hely, Susan M. Edgerton, Neil M. Iyengar, Steven M. Anderson, Carol A. Sartorius, Britta M. Jacobsen, Monica Morrow, Austin E. Gillen
Obesity increases breast cancer mortality by promoting resistance to therapy. Here, we identified regulatory pathways in estrogen receptor-positive (ER-positive) tumors that were shared between patients with obesity and those with resistance to neoad
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::27ca7a6b5e8eb7340e8822effd61187e
https://europepmc.org/articles/PMC6124402/
https://europepmc.org/articles/PMC6124402/
Autor:
Sonali Jindal, Rebecca M. Foright, Ann D. Thor, Erin D. Giles, Pepper Schedin, Steven M. Anderson, Peter Kabos, Elizabeth A. Wellberg, Robera Oljira, Susan M. Edgerton, Paul S. MacLean, Reema Wahdan-Alaswad, L. Allyson Checkley, Stevi J. Johnson, Greg Dooley, Ginger C. Johnson, Jennifer K. Richer
The androgen receptor (AR) has context-dependent roles in breast cancer growth and progression. Overall, high tumor AR levels predict a favorable patient outcome, but several studies have established a tumor promotional role for AR, particularly in s
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b8b9fe786ea1e8770e472b3c4cdda7d3
https://europepmc.org/articles/PMC6022404/
https://europepmc.org/articles/PMC6022404/
Autor:
Patrick D. Rädler, Barbara L. Wehde, Kay Uwe Wagner, Hridaya Shrestha, Aleata A. Triplett, Stevi J. Johnson
Publikováno v:
Cell Reports, Vol 25, Iss 8, Pp 2192-2207.e5 (2018)
Summary: Janus kinases (JAKs) and their downstream STAT proteins play key roles in cytokine signaling, tissue homeostasis, and cancer development. Using a breast cancer model that conditionally lacks Janus kinase 1, we show here that JAK1 is essentia
Autor:
Stevi J. Johnson, E. Dale Abel, Elizabeth A. Wellberg, Jessica Finlay-Schultz, Kristina L. Terrell, Andrew S. Lewis, Carol A. Sartorius, Steven M. Anderson, William J. Muller
Publikováno v:
Breast Cancer Research : BCR
Background Altered tumor cell metabolism is an emerging hallmark of cancer; however, the precise role for glucose in tumor initiation is not known. GLUT1 (SLC2A1) is expressed in breast cancer cells and is likely responsible for avid glucose uptake o
Autor:
Steven M. Anderson, Elizabeth A. Wellberg, Peter Kabos, Stevi J. Johnson, Paul S. MacLean, Carol A. Sartorius, Britta M. Jacobsen
Publikováno v:
Cancer Research. 78:P5-05
Background: More than 200,000 women are diagnosed with breast cancer each year and 75% develop estrogen receptor positive (ER+) tumors. Obesity is an independent risk factor for the development of ER+ breast cancer, particularly after menopause, and