Structure-based design and characterization of Parkin-activating mutations.

Autor: Stevens MU; MRC Protein Phosphorylation and Ubiquitylation Unit, School of Life Sciences, University of Dundee, Dundee, UK., Croteau N; Department of Pharmacology & Therapeutics, McGill University, Montréal, Canada.; Centre de Recherche en Biologie Structurale, Montpellier, France., Eldeeb MA; McGill Parkinson Program, Montreal Neurological Institute, McGill University, Montreal, Canada., Antico O; MRC Protein Phosphorylation and Ubiquitylation Unit, School of Life Sciences, University of Dundee, Dundee, UK., Zeng ZW; Department of Pharmacology & Therapeutics, McGill University, Montréal, Canada., Toth R; MRC Protein Phosphorylation and Ubiquitylation Unit, School of Life Sciences, University of Dundee, Dundee, UK., Durcan TM; McGill Parkinson Program, Montreal Neurological Institute, McGill University, Montreal, Canada., Springer W; Department of Neuroscience, Mayo Clinic, Jacksonville, FL, USA.; Neuroscience PhD Program, Mayo Clinic Graduate School of Biomedical Sciences, Jacksonville, FL, USA., Fon EA; McGill Parkinson Program, Montreal Neurological Institute, McGill University, Montreal, Canada ted.fon@mcgill.ca m.muqit@dundee.ac.uk jeanfrancois.trempe@mcgill.ca., Muqit MM; MRC Protein Phosphorylation and Ubiquitylation Unit, School of Life Sciences, University of Dundee, Dundee, UK ted.fon@mcgill.ca m.muqit@dundee.ac.uk jeanfrancois.trempe@mcgill.ca., Trempe JF; Department of Pharmacology & Therapeutics, McGill University, Montréal, Canada ted.fon@mcgill.ca m.muqit@dundee.ac.uk jeanfrancois.trempe@mcgill.ca.; Centre de Recherche en Biologie Structurale, Montpellier, France.

Publikováno v: Life science alliance [Life Sci Alliance] 2023 Mar 20; Vol. 6 (6). Date of Electronic Publication: 2023 Mar 20 (Print Publication: 2023).