Zobrazeno 1 - 10
of 41
pro vyhledávání: '"Steven Zimmerly"'
Publikováno v:
PLoS ONE, Vol 7, Iss 11, p e49225 (2012)
Tetraloop-receptor interactions are prevalent structural units in RNAs, and include the GAAA/11-nt and GNRA-minor groove interactions. In this study, we have compiled a set of 78 nonredundant loop-helix interactions from X-ray crystal structures, and
Externí odkaz:
https://doaj.org/article/16a9c9179b044fc6a30f1f85e5309429
Autor:
Li Wu, Amy Du, Mechthild Pohlschroder, Kharissa L Shaw, Mari Gingery, Hamza Khan, Michael Abebe, Sumit Handa, Diego Arambula, Elizabeth Czornyj, Partho Ghosh, Jeff F. Miller, Huatao Guo, Steven Zimmerly, Minghsun Liu
Publikováno v:
Nucleic Acids Research
Nucleic acids research, vol 46, iss 1
Wu, L; Gingery, M; Abebe, M; Arambula, D; Czornyj, E; Handa, S; et al.(2018). Diversity-generating retroelements: Natural variation, classification and evolution inferred from a large-scale genomic survey. Nucleic Acids Research, 46(1), 11-24. doi: 10.1093/nar/gkx1150. UC San Diego: Retrieved from: http://www.escholarship.org/uc/item/1q07714k
Nucleic acids research, vol 46, iss 1
Wu, L; Gingery, M; Abebe, M; Arambula, D; Czornyj, E; Handa, S; et al.(2018). Diversity-generating retroelements: Natural variation, classification and evolution inferred from a large-scale genomic survey. Nucleic Acids Research, 46(1), 11-24. doi: 10.1093/nar/gkx1150. UC San Diego: Retrieved from: http://www.escholarship.org/uc/item/1q07714k
© The Author(s) 2017. Diversity-generating retroelements (DGRs) are novel genetic elements that use reverse transcription to generate vast numbers of sequence variants in specific target genes. Here, we present a detailed comparative bioinformatic a
Autor:
Bonnie A. McNeil, Steven Zimmerly
Publikováno v:
RNA. 20:855-866
Group II introns are ribozymes in bacterial and organellar genomes that function as self-splicing introns and as retroelements. Previously, we reported that the group II intron C.te.I1 of Clostridium tetani alternatively splices in vivo to produce fi
Autor:
Li Wu, Adrian Duong, Runda Sun, Ashley M. Jarding, tony Li, Keyar S. Hood, Ryan A. E. Neufeld, Steven Zimmerly, Bonnie A. McNeil, Michael A Candales
Publikováno v:
Nucleic Acids Research
The Database for Bacterial Group II Introns (http://webapps2.ucalgary.ca/~groupii/index.html#) provides a catalogue of full-length, non-redundant group II introns present in bacterial DNA sequences in GenBank. The website is divided into three sectio
Publikováno v:
Nucleic Acids Research
Reverse transcriptases (RTs) are RNA-dependent DNA polymerases that usually function in the replication of selfish DNAs such as retrotransposons and retroviruses. Here, we have biochemically characterized a RT-related protein, AbiK, which is required
Autor:
Dawn M. Simon, Steven Zimmerly
Publikováno v:
Nucleic Acids Research
Retroelements are usually considered to be eukaryotic elements because of the large number and variety in eukaryotic genomes. By comparison, reverse transcriptases (RTs) are rare in bacteria, with only three characterized classes: retrons, group II i
Autor:
Dinggeng Chai, Alan M. Lambowitz, Steven Zimmerly, Forrest Blocker, Lixin Dai, Jesse Gabel, Shan Qing Gu, Sergei Y. Noskov
Publikováno v:
Molecular Cell. 30:472-485
Group II introns are self-splicing ribozymes believed to be the ancestors of spliceosomal introns. Many group II introns encode reverse transcriptases that promote both RNA splicing and intron mobility to new genomic sites. Here we used a circular pe
Publikováno v:
Wiley interdisciplinary reviews. RNA. 7(3)
Group II introns are catalytic RNAs (ribozymes) and retroelements found in the genomes of bacteria, archaebacteria, and organelles of some eukaryotes. The prototypical retroelement form consists of a structurally conserved RNA and a multidomain rever
Autor:
Steven Zimmerly, Li Wu
Publikováno v:
Microbiology spectrum. 3(2)
Reverse transcriptases (RTs) are usually thought of as eukaryotic enzymes, but they are also present in bacteria and likely originated in bacteria and migrated to eukaryotes. Only three types of bacterial retroelements have been substantially charact