Zobrazeno 1 - 10
of 95
pro vyhledávání: '"Steven Y. Cheng"'
Autor:
Jing Cai, Yue Wang, Xinfa Wang, Zihe Ai, Tianyuan Li, Xiaohong Pu, Xin Yang, Yixing Yao, Junping He, Steven Y. Cheng, Tingting Yu, Chen Liu, Shen Yue
Publikováno v:
Cell & Bioscience, Vol 13, Iss 1, Pp 1-17 (2023)
Abstract Background Medulloblastoma (MB) is one of the most common malignant pediatric brain tumors. Metastasis and relapse are the leading causes of death in MB patients. The initiation of the SHH subgroup of MB (SHH-MB) is due to the aberrant activ
Externí odkaz:
https://doaj.org/article/f08326003f6b4b4eb210e38bca18f459
Publikováno v:
Frontiers in Cell and Developmental Biology, Vol 10 (2022)
Externí odkaz:
https://doaj.org/article/fe75e4286a9c494393bf1fd388207850
Autor:
Bo’ang Han, Zhen Sun, Tingting Yu, Yu Wang, Lun Kuang, Tianyuan Li, Jing Cai, Qing Cao, Yuan Xu, Binbin Gao, Steven Y. Cheng, Shen Yue, Chen Liu
Publikováno v:
Cell Death Discovery, Vol 7, Iss 1, Pp 1-15 (2021)
Abstract Although E3 ligase Speckle type BTB/POZ protein (SPOP) promotes tumorigenesis by acting as a key regulatory hub in clear cell renal cell carcinoma (ccRCC), the detailed molecular mechanism remains unclear. Here, we demonstrate that a well-kn
Externí odkaz:
https://doaj.org/article/31de90bce9004154b8f7953a5e555793
Autor:
Ting-ting Yu, Qiu-fan Xu, Si-Yang Li, Hui-jie Huang, Sarah Dugan, Lei Shao, Jennifer A. Roggenbuck, Xiao-tong Liu, Huai-ze Liu, Betsy A. Hirsch, Shen Yue, Chen Liu, Steven Y. Cheng
Publikováno v:
Cell & Bioscience, Vol 11, Iss 1, Pp 1-15 (2021)
Abstract Background Skeletal development and maintenance are complex processes known to be coordinated by multiple genetic and epigenetic signaling pathways. However, the role of long non-coding RNAs (lncRNAs), a class of crucial epigenetic regulator
Externí odkaz:
https://doaj.org/article/0e2c6b9da70c4d81bcc79ae4a4241d05
Autor:
Junwan Fan, Haowen Li, Lun Kuang, Zichen Zhao, Wenyan He, Chen Liu, Yongjun Wang, Steven Y. Cheng, Wei Chen
Publikováno v:
Cell & Bioscience, Vol 11, Iss 1, Pp 1-11 (2021)
Abstract Background Hedgehog signaling is essential to the regulation of embryonic development, tissue homeostasis, and stem cell self-renewal, making it a prime target for developing cancer therapeutics. Given the close link between aberrant Hedgeho
Externí odkaz:
https://doaj.org/article/054017eb11d94654ab20711938c4b523
Autor:
Wang, Meng, Liu, Shouguo, Peng, Zhihang, Zhu, Yi, Feng, Xiaodong, Gu, Yihuang, Sun, Jianhua, Tang, Qiang, Chen, Hongxia, Huang, Xiaolin, Hu, Jun, Chen, Wei, Xiang, Jie, Wan, ChunXiao, Fan, Gangqi, Lu, Jianhu, Xia, Wenguang, Lihua Wang, Steven Y. Cheng, Lu, Xiao, Li, Jianan
Publikováno v:
In Journal of the American Medical Directors Association March 2020 21(3):374-380
Publikováno v:
Scientific Reports, Vol 7, Iss 1, Pp 1-14 (2017)
Abstract The morphogenic factor Sonic hedgehog (Shh) signals through the primary cilium, which relies on intraflagellar transport to maintain its structural integrity and function. However, the process by which protein and lipid cargos are delivered
Externí odkaz:
https://doaj.org/article/e5210e7b77f24980b5cd040dcfcd662c
Autor:
Yixing Yao, Tianyuan Li, Tingting Yu, Xin Yang, Yue Wang, Jing Cai, Steven Y. Cheng, Chen Liu, Shen Yue
Publikováno v:
Biochemistry and Cell Biology.
Studies in the past decade have shown that lipid droplets stored in liver cells under starvation are encapsulated by autophagosomes and fused to lysosomes via the endocytic system. Autophagy responds to a variety of environmental factors inside and o
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::e140c25c5c753e8a2600d880299141c1
https://doi.org/10.1139/bcb-2022-0345
https://doi.org/10.1139/bcb-2022-0345
Autor:
Jing Cai, Yue Wang, Xinfa Wang, Zihe Ai, Tianyuan Li, Xiaohong Pu, Xin Yang, Yixing Yao, Junping He, Steven Y. Cheng, Tingting Yu, Chen Liu, Shen Yue
Background Medulloblastoma (MB) is one of the most common malignant pediatric brain tumors. Metastasis and relapse are the leading causes of death in MB patients. The initiation of the SHH subgroup of MB (SHH-MB) is due to the aberrant activation of
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b8e39c35c9593d94e1e9d1cc51edfca2
https://doi.org/10.21203/rs.3.rs-2073579/v1
https://doi.org/10.21203/rs.3.rs-2073579/v1
Publikováno v:
eLife, Vol 5 (2016)
Hedgehog signaling plays very important roles in development and cancers. Vertebrates have three transcriptional factors, Gli1, Gli2 and Gli3. Among them, Gli3 is a very special transcriptional factor which closely resembles Cubitus interruptus (Ci,
Externí odkaz:
https://doaj.org/article/8d92cf90ebc04c318130e9b508815d53