MicroRNA sequencing of rat hippocampus and human biofluids identifies acute, chronic, focal and diffuse traumatic brain injuries

Autor: Harris A. Weisz, Deborah Kennedy, Steven Widen, Heidi Spratt, Stacy L. Sell, Christine Bailey, Melinda Sheffield-Moore, Douglas S. DeWitt, Donald S. Prough, Harvey Levin, Claudia Robertson, Helen L. Hellmich

Publikováno v: Scientific Reports, Vol 10, Iss 1, Pp 1-10 (2020)

Abstract High-throughput sequencing technologies could improve diagnosis and classification of TBI subgroups. Because recent studies showed that circulating microRNAs (miRNAs) may serve as noninvasive markers of TBI, we performed miRNA-seq to study T

Externí odkaz: https://doaj.org/article/c734795419e6481684153ad2356800bb

Characterizing molecular subtypes of high-risk non-muscle-invasive bladder cancer in African American patients

Autor: Sungyong You, Minhyung Kim, Steven Widen, Alexander Yu, Gloria C. Galvan, Yunhee Choi-Kuaea, Eduardo J. Eyzaguirre, Lars Dyrskjøt, David J. McConkey, Woonyoung Choi, Dan Theodorescu, Keith S. Chan, Yong Shan, Douglas S. Tyler, Amanda M. De Hoedt, Stephen J. Freedland, Stephen B. Williams

Publikováno v: You, S, Kim, M, Widen, S, Yu, A, Galvan, G C, Choi-Kuaea, Y, Eyzaguirre, E J, Dyrskjøt, L, McConkey, D J, Choi, W, Theodorescu, D, Chan, K S, Shan, Y, Tyler, D S, De Hoedt, A M, Freedland, S J & Williams, S B 2022, ' Characterizing molecular subtypes of high-risk non-muscle-invasive bladder cancer in African American patients ', Urologic Oncology: Seminars and Original Investigations, vol. 40, no. 9, pp. 410.e19-410.e27 . https://doi.org/10.1016/j.urolonc.2022.04.013

Background: We sought to determine whether differences in subtype distribution and differentially expressed genes exist between African Americans (AAs) and European Americans (EAs) in patients with high-risk nonmuscle-invasive bladder cancer (NMIBC).

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::25403570ccc7b6b0d29509ccc7152f7f
https://pure.au.dk/portal/da/publications/characterizing-molecular-subtypes-of-highrisk-nonmuscleinvasive-bladder-cancer-in-african-american-patients(6d8a2fb7-40d4-4da5-9848-1cb5dc4513ee).html

Abstract 321: RBFOX2 is critical for maintaining alternative polyadenylation patterns in cardiomyoblasts

Autor: Andrew L Routh, Jun Cao, Curtis A. Nutter, Kempaiah Rayavara, Ela Jaworski, Steven Widen, Nathan Elrod, Ping Ji, Nisha J Garg, Muge N. Kuyumcu-Martinez, Sunil Verma, KarryAnne Belanger, Eric J. Wagner

Publikováno v: Circulation Research. 125

Background: The RNA binding protein RBFOX2 is implicated in human heart diseases. However, RBFOX2-regulated RNA networks are not well defined. RBFOX2 has a well-characterized role in alternative splicing (AS) while accumulating evidence suggests that

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::5327c566131605acd24455cb2ef6a463
https://doi.org/10.1161/res.125.suppl_1.321