Zobrazeno 1 - 10
of 89
pro vyhledávání: '"Steven W. Martin"'
Autor:
Katharine V. Rogers, Steven W. Martin, Indranil Bhattacharya, Ravi Shankar Prasad Singh, Satyaprakash Nayak
Publikováno v:
Clinical and Translational Science, Vol 14, Iss 1, Pp 239-248 (2021)
A mechanistic, multistate, mathematical model of inflammatory bowel disease (IBD) was developed by including key biological mechanisms in blood and gut, including cell differentiation, cytokine production, and clinical biomarkers. The model structure
Externí odkaz:
https://doaj.org/article/0a3d1190366a42eea5158adfd4d3f6be
Autor:
Katharine V. Rogers, Steven W. Martin, Indranil Bhattacharya, Ravi Shankar Prasad Singh, Satyaprakash Nayak
Publikováno v:
Clinical and Translational Science, Vol 14, Iss 1, Pp 249-259 (2021)
Inflammatory bowel disease (IBD) is a heterogeneic disease with a variety of treatments targeting different mechanisms. A multistate, mechanistic, mathematical model of IBD was developed in part 1 of this two‐part article series. In this paper, app
Externí odkaz:
https://doaj.org/article/6323044eec1e4d869f3694b917d9f860
Autor:
Sarah J. Schrieber, Wendy S. Putnam, Edwin Chiu Yuen Chow, Jacek Cieslak, Yanli Zhuang, Steven W. Martin, Paul Hanson, Frank Maggio, Leslie A. Rivera Rosado
Publikováno v:
Drugs in R&D, Vol 20, Iss 4, Pp 301-306 (2020)
Abstract Expedited development programs for biological products to be used in the treatment of serious conditions bring about challenges because of the compressed clinical development timeframes. As expedited development does not lessen the quality e
Externí odkaz:
https://doaj.org/article/a3da12607df14469b1768c5c0151d180
Autor:
Jonathan C. Walton, Dayton M. Lambert, Roland K. Roberts, James A. Larson, Burton C. English, Sherry L. Larkin, Steven W. Martin, Michele C. Marra, Kenneth W. Paxton, Jeanne M. Reeves
Publikováno v:
Journal of Agricultural and Resource Economics, Vol 33, Iss 3, Pp 428-448 (2008)
Adoption of precision agriculture technology has arrived considerable attention, but abandonment has received little. This paper identified factors motivating adoption and abandonment of precision soils sampling in cotton. Younger producers who farme
Externí odkaz:
https://doaj.org/article/29278bbed78d4cc9948dfbf206c357b2
Publikováno v:
Journal of Agricultural and Resource Economics, Vol 26, Iss 1, Pp 261-274 (2001)
Production agriculture and agribusiness are exposed to many weather-related risks. Recent years have seen the emergence of an increased interest in weather-based derivatives as mechanisms for sharing risks due to weather phenomena. In this study, a u
Externí odkaz:
https://doaj.org/article/be83440248c44c1e93faac3d8418fb81
Autor:
Anindita Banerjee, Edouard Louis, Satyaprakash Nayak, Jochen Klaus, Kenneth J. Gorelick, Stefan Schreiber, Steven W. Martin, William J. Sandborn, Maria Kłopocka, Geert R. D'Haens, Xavier Hébuterne, Scott D. Lee, Fabio Cataldi, Peter Nagy, Walter Reinisch, Dino Tarabar, Dong Il Park
Publikováno v:
Inflammatory bowel diseases, 28(7), 1034-1044. John Wiley and Sons Inc.
Background Patients with Crohn’s disease (CD) experience intestinal inflammation. Ontamalimab (SHP647), a fully human immunoglobulin G2 monoclonal antibody against mucosal addressin cell adhesion molecule-1, is a potential novel CD treatment. OPERA
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::42c598bd58d2a3ecd2978a58a504cb71
https://doi.org/10.1093/ibd/izab215
https://doi.org/10.1093/ibd/izab215
Autor:
Indranil Bhattacharya, Katharine V. Rogers, Steven W. Martin, Satyaprakash Nayak, Ravi Shankar P. Singh
Publikováno v:
Clinical and Translational Science, Vol 14, Iss 1, Pp 249-259 (2021)
Clinical and Translational Science
Clinical and Translational Science
Inflammatory bowel disease (IBD) is a heterogeneic disease with a variety of treatments targeting different mechanisms. A multistate, mechanistic, mathematical model of IBD was developed in part 1 of this two-part article series. In this paper, appli
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e992aa483c5edadc964faf6e4957df7f
https://doaj.org/article/6323044eec1e4d869f3694b917d9f860
https://doaj.org/article/6323044eec1e4d869f3694b917d9f860
Autor:
Anasuya Hazra, Wojciech Niezychowski, Arnab Mukherjee, Chinyu Su, Mike K. Smith, Diane R. Mould, Steven W. Martin
Publikováno v:
British Journal of Clinical Pharmacology. 84:1136-1145
Aims Tofacitinib is an oral, small molecule JAK inhibitor being investigated for ulcerative colitis (UC). In a phase 2 dose-ranging study, tofacitinib demonstrated efficacy vs. placebo as UC induction therapy. In this posthoc analysis, we aimed to co
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::94704e247e8cd404b0a2eea9fe285d1e
https://doi.org/10.1111/bcp.13523
https://doi.org/10.1111/bcp.13523
Publikováno v:
Clinical and Translational Science. 11:4-7
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::dce2722d5fc0dbe1fbc3533bf0760a2c
https://doi.org/10.1111/cts.12503
https://doi.org/10.1111/cts.12503
Autor:
Steven W. Martin, Hendrik Neubert, David von Schack, Padma Reddy, Fabio Cataldi, Mina Hassan-Zahraee, John B. Cheng, Clare Robert A, Kenneth E. Hung, Karen Page, Baohong Zhang, Alaa Ahmad, Satyaprakash Nayak, Anindita Banerjee, Ken Gorelick, Mireia Fernández Ocaña, Li Xi, Michael S. Vincent, Weidong Zhang
Publikováno v:
Journal of Crohn's & Colitis
Objective To define pharmacodynamic biomarkers in the peripheral blood of patients with Crohn’s disease [CD] after treatment with PF-00547659, an anti-human mucosal addressin cell adhesion molecule-1 [MAdCAM-1] monoclonal antibody. Methods In this
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::395531914c3120f89bf780003042e390
https://doi.org/10.1093/ecco-jcc/jjx121
https://doi.org/10.1093/ecco-jcc/jjx121