Zobrazeno 1 - 10
of 12
pro vyhledávání: '"Steven W. Harbaugh"'
Autor:
Anthony Cook, Miriam C. Poirier, Maryanne M. Kuo, Rao L. Divi, Tracey L. Einem, Jeffrey W. Harbaugh, Steven W. Harbaugh, Kunio Nagashima, Marie E. Shockley, Marisa St. Claire, Sarah L. Leonard Fletcher
Publikováno v:
Toxicological Sciences. 118:191-201
Mitochondrial compromise has been documented in infants born to women infected with the human immunodeficiency virus (HIV-1) who received nucleoside reverse transcriptase inhibitor (NRTI) therapy during pregnancy. To model these human exposures, we e
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3917a75a6250fe82d0fd046cf9da1cb9
https://doi.org/10.1093/toxsci/kfq235
https://doi.org/10.1093/toxsci/kfq235
Autor:
Miriam C. Poirier, Craig A. Sable, Marisa St. Claire, Maryanne M. Kuo, Sarah L. Leonard, Chandrasekhar Thamire, Steven W. Harbaugh, Kunio Nagashima, Christine C. Orozco, Rao L. Divi, Jeffrey W. Harbaugh, Brettania L. Walker
Publikováno v:
Cardiovascular Toxicology. 5:333-346
Hearts from 1-yr-old Erythrocebus patas monkeys were examined after in utero and 6-wk-postbirth exposure to antiretroviral nucleoside reverse transcriptase inhibitors (NRTIs). Protocols were modeled on those given to human immunodeficiency virus (HIV
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::b84c0774ee5fb95a4a21f223f6d139fc
https://doi.org/10.1385/ct:5:3:333
https://doi.org/10.1385/ct:5:3:333
Autor:
Mariana Gerschenson, Kunio Nagashima, Marisa St. Claire, Boris Skopets, Ember L. Ewings, Jeffery W. Harbaugh, Steven W. Harbaugh, Miriam C. Poirier
Publikováno v:
JAIDS Journal of Acquired Immune Deficiency Syndromes. 24:100-105
Mitochondrial toxicity was assessed in the brains of developing Erythrocebus patas monkey fetuses exposed in utero to the nucleoside analogue drug zidovudine (3'-azido-3'deoxythymidine or AZT). Pregnant E. patas monkeys were given 0 (n = 5), 10 (n =
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::111683116392e81cc0d8e30eb6b54dbe
https://doi.org/10.1097/00126334-200006010-00003
https://doi.org/10.1097/00126334-200006010-00003
Autor:
Bhalchandra A. Diwan, Jerry M. Rice, Daniel Logsdon, Ann B. Jones, Miriam C. Poirier, Chaoyu Wang, Stuart H. Yuspa, Charles W. Riggs, Ofelia A. Olivero, Thomas J. Moskal, Steven W. Harbaugh, Lucy M. Anderson, Diana C. Haines
Publikováno v:
JNCI Journal of the National Cancer Institute. 89:1602-1608
Background: When given during pregnancy, the drug 3'-azido-2',3'-dideoxy-thymidine (AZT) substantially reduces maternal-fetal transmission of human immunodeficiency virus type 1 (HIV-1). However, AZT has been shown to be carcinogenic in adult mice af
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::02058daca41011e81e0df8b42eb9cfd9
https://doi.org/10.1093/jnci/89.21.1602
https://doi.org/10.1093/jnci/89.21.1602
Autor:
Daniel R. Doerge, Jeffrey W. Harbaugh, Steven W. Harbaugh, Miriam C. Poirier, Marie E. Shockley, Marisa St. Claire, Rao L. Divi, Nathan C. Twaddle
Publikováno v:
Toxicology and applied pharmacology. 226(2)
Because of their similarity to humans, non-human primates constitute useful preclinical models in which to examine potential human drug toxicities. Antiretroviral nucleoside reverse transcriptase inhibitor (NRTI) toxicity is currently under investiga
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8102fce5a9a1f62da75b130fbf7e9a14
https://pubmed.ncbi.nlm.nih.gov/17949768
https://pubmed.ncbi.nlm.nih.gov/17949768
Autor:
Kunio Nagashima, Marisa St. Claire, Steven W. Harbaugh, Jeffrey W. Harbaugh, Brettania L. Walker, Miriam C. Poirier, Marie E. Shockley, Sarah L. Leonard, Maryanne M. Kuo, Rao L. Divi
Publikováno v:
Toxicological sciences : an official journal of the Society of Toxicology. 99(1)
Antiretroviral nucleoside reverse transcriptase inhibitors (NRTIs), given to human immunodeficiency virus-1-infected pregnant women to prevent vertical viral transmission, have caused mitochondrial dysfunction in some human infants. Here, we examined
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e2fb672d994097a61819544faff14936
https://pubmed.ncbi.nlm.nih.gov/17545213
https://pubmed.ncbi.nlm.nih.gov/17545213
Autor:
Rao L, Divi, Sarah L, Leonard, Maryanne M, Kuo, Brettania L, Walker, Christine C, Orozco, Marisa C, St Claire, Kunio, Nagashima, Steven W, Harbaugh, Jeffrey W, Harbaugh, Chandrasekhar, Thamire, Craig A, Sable, Miriam C, Poirier
Publikováno v:
Cardiovascular toxicology. 5(3)
Hearts from 1-yr-old Erythrocebus patas monkeys were examined after in utero and 6-wk-postbirth exposure to antiretroviral nucleoside reverse transcriptase inhibitors (NRTIs). Protocols were modeled on those given to human immunodeficiency virus (HIV
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::8154a41de2fbfd65d65257d45b80f68f
https://pubmed.ncbi.nlm.nih.gov/16244378
https://pubmed.ncbi.nlm.nih.gov/16244378
Autor:
Jeffrey W. Harbaugh, Vi Nguyen, Paul S. Albert, Ember L. Ewings, Miriam C. Poirier, Rao L. Divi, Ofelia A. Olivero, Marisa St. Claire, Kunio Nagashima, Jaclyn A. Shaw, Steven W. Harbaugh, Mariana Gerschenson, Andrea Ceresa
Publikováno v:
AIDS research and human retroviruses. 20(1)
This study was designed to investigate fetal mitochondrial toxicity in Erythrocebus patas monkeys exposed in utero to zidovudine (AZT) and lamivudine (3TC), and taken at term. Pregnant patas monkeys were given a daily dose of 40 mg AZT (86% of the hu
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7e4a7396246cc8c3408ac8e3bde01958
https://pubmed.ncbi.nlm.nih.gov/15000702
https://pubmed.ncbi.nlm.nih.gov/15000702
Autor:
Boris Skopets, Stephen W . Erhart, Jeffrey W. Harbaugh, Marisa St. Claire, Miriam C. Poirier, Mariana Gerschenson, Catherine Y. Paik, Steven W. Harbaugh, Wing Quan, Kunio Nagashima
Publikováno v:
AIDS research and human retroviruses. 16(7)
3'-azido-3'-deoxythymidine (AZT) is given to pregnant women positive for the human immunodeficiency virus type 1 (HIV-1) to reduce maternal-fetal viral transmission. To explore fetal mitochondrial consequences of this exposure, pregnant Erythrocebus
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4c037986f649b4a9eee3c7a05b13281d
https://pubmed.ncbi.nlm.nih.gov/10791874
https://pubmed.ncbi.nlm.nih.gov/10791874
Autor:
Mariana Gerschenson, Vi Nguyen, Ember L. Ewings, Andrea Ceresa, Jaclyn A. Shaw, Marisa C. St. Claire, Kunio Nagashima, Steven W. Harbaugh, Jeffrey W. Harbaugh, Ofelia A. Olivero, Rao L. Divi, Paul S. Albert, Miriam C. Poirier
Publikováno v:
AIDS Research & Human Retroviruses; Jan2004, Vol. 20 Issue 1, p91-100, 10p