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pro vyhledávání: '"Steven W. Cummings"'
Publikováno v:
Chemical Communications. 58:6530-6533
Tubulin polyglycylation is a posttranslational modification that occurs primarily on the axonemes of flagella and cilia and has been shown to be essential for proper sperm motility. Inhibitors of both the initiase and elongase ligases (TTLL8 and TTLL
Autor:
Ewa Szczesna, Elena A. Zehr, Steven W. Cummings, Agnieszka Szyk, Kishore K. Mahalingan, Yan Li, Antonina Roll-Mecak
Publikováno v:
Developmental cell. 57(21)
Microtubules have spatiotemporally complex posttranslational modification patterns. How cells interpret this tubulin modification code is largely unknown. We show that C. elegans katanin, a microtubule severing AAA ATPase mutated in microcephaly and