Zobrazeno 1 - 10
of 14
pro vyhledávání: '"Steven W. Bothwell"'
Autor:
Daniel Omileke, Sara Azarpeykan, Steven W. Bothwell, Debbie Pepperall, Daniel J. Beard, Kirsten Coupland, Adjanie Patabendige, Neil J. Spratt
Publikováno v:
Scientific Reports, Vol 11, Iss 1, Pp 1-9 (2021)
Abstract Reperfusion therapies re-establish blood flow after arterial occlusion and improve outcome for ischaemic stroke patients. Intracranial pressure (ICP) elevation occurs 18–24 h after experimental stroke. This elevation is prevented by short-
Externí odkaz:
https://doaj.org/article/92a4ab37e1844ea2bc81fdc3d482f947
Autor:
Daniel Omileke, Debbie Pepperall, Steven W. Bothwell, Nikolce Mackovski, Sara Azarpeykan, Daniel J. Beard, Kirsten Coupland, Adjanie Patabendige, Neil J. Spratt
Publikováno v:
Frontiers in Neurology, Vol 12 (2021)
There is a transient increase in intracranial pressure (ICP) 18–24 h after ischaemic stroke in rats, which is prevented by short-duration hypothermia using rapid cooling methods. Clinical trials of long-duration hypothermia have been limited by fea
Externí odkaz:
https://doaj.org/article/143733157fac49edb8a0231418e87c47
Autor:
Steven W. Bothwell, Daniel Omileke, Rebecca J. Hood, Debbie-Gai Pepperall, Sara Azarpeykan, Adjanie Patabendige, Neil J. Spratt
Publikováno v:
Frontiers in Molecular Neuroscience, Vol 14 (2021)
Oedema-independent intracranial pressure (ICP) rise peaks 20–22-h post-stroke in rats and may explain early neurological deterioration. Cerebrospinal fluid (CSF) volume changes may be involved. Cranial CSF clearance primarily occurs via the cervica
Externí odkaz:
https://doaj.org/article/519dc5f1accd41c3a0023cba3cb88752
Autor:
Daniel Omileke, Steven W. Bothwell, Debbie Pepperall, Daniel J. Beard, Kirsten Coupland, Adjanie Patabendige, Neil J. Spratt
Publikováno v:
Brain Sciences, Vol 11, Iss 12, p 1589 (2021)
Background: Elevated intracranial pressure (ICP) occurs 18–24 h after ischaemic stroke and is implicated as a potential cause of early neurological deterioration. Increased resistance to cerebrospinal fluid (CSF) outflow after ischaemic stroke is a
Externí odkaz:
https://doaj.org/article/6d250e56b68c4c3882450a19dde75d1d
Publikováno v:
Brain Sciences, Vol 11, Iss 9, p 1117 (2021)
Background: Cerebrospinal fluid (CSF) secretion can be targeted to reduce elevated intracranial pressure (ICP). Sodium-potassium-chloride cotransporter 1 (NKCC1) antagonism is used clinically. However, supporting evidence is limited. The transient re
Externí odkaz:
https://doaj.org/article/9a8237a653df4a81b8c62f5cb7988ce9
Autor:
Steven W. Bothwell, Daniel J. Beard, Kirsten Coupland, Daniel Omileke, Neil J. Spratt, Adjanie Patabendige, Debbie Pepperall
Publikováno v:
Brain Sciences; Volume 11; Issue 12; Pages: 1589
Brain Sciences, Vol 11, Iss 1589, p 1589 (2021)
Brain Sciences
BRAIN SCIENCES
Brain Sciences, Vol 11, Iss 1589, p 1589 (2021)
Brain Sciences
BRAIN SCIENCES
Background: Elevated intracranial pressure (ICP) occurs 18–24 h after ischaemic stroke and is implicated as a potential cause of early neurological deterioration. Increased resistance to cerebrospinal fluid (CSF) outflow after ischaemic stroke is a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::28d05bcaf98a414ccd957df53c8170bb
Publikováno v:
BRAIN SCIENCES
Brain Sciences
Brain Sciences, Vol 11, Iss 1117, p 1117 (2021)
Volume 11
Issue 9
Brain Sciences
Brain Sciences, Vol 11, Iss 1117, p 1117 (2021)
Volume 11
Issue 9
Background: Cerebrospinal fluid (CSF) secretion can be targeted to reduce elevated intracranial pressure (ICP). Sodium-potassium-chloride cotransporter 1 (NKCC1) antagonism is used clinically. However, supporting evidence is limited. The transient re
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3dbe229375ab77dd2f7206e76eb39d7f
Autor:
Daniel Omileke, Sara Azarpeykan, Steven W Bothwell, Debbie Pepperall, Daniel J Beard, Kirsten Coupland, Adjanie Patabendige, Neil J Spratt
Reperfusion therapies re-establish blood flow after arterial occlusion and improve outcome for ischaemic stroke patients. Intracranial pressure (ICP) elevation occurs 18–24 h after experimental stroke. This elevation is prevented by short-duration
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::d96c3d8a4de9605cc97bc94c7f9c98b9
https://doi.org/10.21203/rs.3.rs-846595/v1
https://doi.org/10.21203/rs.3.rs-846595/v1
Autor:
Kirsten Coupland, Daniel J. Beard, Steven W. Bothwell, Sara Azarpeykan, Daniel Omileke, Adjanie Patabendige, Nikolce Mackovski, Neil J. Spratt
Publikováno v:
Journal of Visualized Experiments.
Therapeutic hypothermia (TH) is a powerful neuroprotective strategy that has provided robust evidence for neuroprotection in pre-clinical studies of neurological disorders. Despite strong pre-clinical evidence, TH has not shown efficacy in clinical t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::51ebcd5cbb0b4470721e6638c5f0438a
https://doi.org/10.3791/62325
https://doi.org/10.3791/62325
Background A dramatic oedema-independent intracranial pressure (ICP) rise occurs 24 hours post-stroke in rats and may explain infarct expansion. Underlying mechanisms of this rise are unknown but evidence suggests cerebrospinal fluid (CSF) dynamics a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::a1ab03178230e84011e4b7aa3c781715
https://doi.org/10.21203/rs.3.rs-84123/v1
https://doi.org/10.21203/rs.3.rs-84123/v1