Zobrazeno 1 - 10
of 50
pro vyhledávání: '"Steven W Wingett"'
Autor:
Laetitia Chauve, Francesca Hodge, Sharlene Murdoch, Fatemeh Masoudzadeh, Harry-Jack Mann, Andrea F Lopez-Clavijo, Hanneke Okkenhaug, Greg West, Bebiana C Sousa, Anne Segonds-Pichon, Cheryl Li, Steven W Wingett, Hermine Kienberger, Karin Kleigrewe, Mario de Bono, Michael J O Wakelam, Olivia Casanueva
Publikováno v:
PLoS Biology, Vol 19, Iss 11, p e3001431 (2021)
To survive elevated temperatures, ectotherms adjust the fluidity of membranes by fine-tuning lipid desaturation levels in a process previously described to be cell autonomous. We have discovered that, in Caenorhabditis elegans, neuronal heat shock fa
Externí odkaz:
https://doaj.org/article/8540a2eb797040a69c7c29bcb73e2db0
Autor:
Paula Freire-Pritchett, Stefan Schoenfelder, Csilla Várnai, Steven W Wingett, Jonathan Cairns, Amanda J Collier, Raquel García-Vílchez, Mayra Furlan-Magaril, Cameron S Osborne, Peter Fraser, Peter J Rugg-Gunn, Mikhail Spivakov
Publikováno v:
eLife, Vol 6 (2017)
Long-range cis-regulatory elements such as enhancers coordinate cell-specific transcriptional programmes by engaging in DNA looping interactions with target promoters. Deciphering the interplay between the promoter connectivity and activity of cis-re
Externí odkaz:
https://doaj.org/article/6b57a130ecbc478aaa570feb12bd03e6
Autor:
Olga Mielczarek, Carolyn H. Rogers, Yinxiu Zhan, Louise S. Matheson, Michael J.T. Stubbington, Stefan Schoenfelder, Daniel J. Bolland, Biola M. Javierre, Steven W. Wingett, Csilla Várnai, Anne Segonds-Pichon, Simon J. Conn, Felix Krueger, Simon Andrews, Peter Fraser, Luca Giorgetti, Anne E. Corcoran
Publikováno v:
Cell Reports, Vol 42, Iss 9, Pp 113074- (2023)
Summary: To produce a diverse antibody repertoire, immunoglobulin heavy-chain (Igh) loci undergo large-scale alterations in structure to facilitate juxtaposition and recombination of spatially separated variable (VH), diversity (DH), and joining (JH)
Externí odkaz:
https://doaj.org/article/125cbc8ecfba40ce99ab9245a423021d
Autor:
Mayra Furlan-Magaril, Masami Ando-Kuri, Rodrigo G. Arzate-Mejía, Jörg Morf, Jonathan Cairns, Abraham Román-Figueroa, Luis Tenorio-Hernández, A. César Poot-Hernández, Simon Andrews, Csilla Várnai, Boo Virk, Steven W. Wingett, Peter Fraser
Publikováno v:
Genome Biology, Vol 22, Iss 1, Pp 1-27 (2021)
Abstract Background Circadian gene expression is essential for organisms to adjust their physiology and anticipate daily changes in the environment. The molecular mechanisms controlling circadian gene transcription are still under investigation. In p
Externí odkaz:
https://doaj.org/article/9a210e18686b41e2bfd4786eebcb2e8a
Autor:
Chun Hao Wong, Steven W. Wingett, Chen Qian, J. Matthew Taliaferro, Douglas Ross-Thriepland, Simon L. Bullock
The cytoplasmic dynein-1 (dynein) motor plays a key role in cellular organisation by transporting a wide variety of cellular constituents towards the minus ends of microtubules. However, relatively little is known about how the biosynthesis, assembly
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::21355d6db357473e56d262f912da4507
https://doi.org/10.1101/2023.03.01.530592
https://doi.org/10.1101/2023.03.01.530592
Autor:
Jörg Morf, Luis Felipe Jiménez-García, Steven W. Wingett, Marc A. Marti-Renom, Frank F Craig, Mayra Furlan-Magaril, Liu Xin, Jonathan Cairns, Simon Andrews, Simon Walker, Anne Segonds-Pichon, Irene Farabella, Peter Fraser
Publikováno v:
Nature Biotechnology. 37:793-802
The global, three-dimensional organization of RNA molecules in the nucleus is difficult to determine using existing methods. Here we introduce Proximity RNA-seq, which identifies colocalization preferences for pairs or groups of nascent and fully tra
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::0a49eaa4731624666fe46b1317f36be9
https://doi.org/10.1038/s41587-019-0166-3
https://doi.org/10.1038/s41587-019-0166-3
Autor:
Peter Fraser, Rodrigo G. Arzate-Mejía, Masami Ando-Kuri, Csilla Várnai, Simon Andrews, Jonathan Cairns, Cesar A. Poot Hernández, Jorg Morf, Steven W. Wingett, Boo Virk, Mayra Furlan-Magaril
SummaryCircadian gene expression is essential for organisms to adjust cellular responses and anticipate daily changes in the environment. In addition to its physiological importance, the clock circuit represents an ideal, temporally resolved, system
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::c7b0bccc6f7008e2a44e586af17d903f
https://doi.org/10.1101/2020.07.23.217992
https://doi.org/10.1101/2020.07.23.217992
Autor:
Jörg, Morf, Steven W, Wingett
Publikováno v:
Methods in molecular biology (Clifton, N.J.). 2161
RNA localization is an important regulatory layer of gene expression and cell functioning. The protocol guides through the Proximity RNA-seq method, in which RNA molecules are sequenced in their spatial, cellular context to derive RNA co-localization
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::6b88217e8b4c27f2989862c93d4e8a8c
https://pubmed.ncbi.nlm.nih.gov/32681513
https://pubmed.ncbi.nlm.nih.gov/32681513
Autor:
Steven W. Wingett, Jörg Morf
Publikováno v:
Methods in Molecular Biology ISBN: 9781071606797
RNA localization is an important regulatory layer of gene expression and cell functioning. The protocol guides through the Proximity RNA-seq method, in which RNA molecules are sequenced in their spatial, cellular context to derive RNA co-localization
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::6bb7f42faa010b4f4b304944a9c95324
https://doi.org/10.1007/978-1-0716-0680-3_13
https://doi.org/10.1007/978-1-0716-0680-3_13
Autor:
Carmel Dudley, Yael Baran, Steven W. Wingett, Takashi Nagano, Wing Leung, Netta Mendelson Cohen, Peter Fraser, Amos Tanay, Yaniv Lubling, Csilla Várnai
Publikováno v:
Nature. 547:61-67
Chromosomes in proliferating metazoan cells undergo marked structural metamorphoses every cell cycle, alternating between highly condensed mitotic structures that facilitate chromosome segregation, and decondensed interphase structures that accommoda
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::040dbde39fe25c949e61c0d225bb02a8
https://doi.org/10.1038/nature23001
https://doi.org/10.1038/nature23001