Zobrazeno 1 - 10
of 25
pro vyhledávání: '"Steven W Wang"'
Autor:
Takae Kiyama, Ching-Kang Chen, Steven W Wang, Ping Pan, Zhenlin Ju, Jing Wang, Shinako Takada, William H Klein, Chai-An Mao
Publikováno v:
Molecular Neurodegeneration, Vol 13, Iss 1, Pp 1-23 (2018)
Abstract Background Mitochondrial dysfunction has been implicated in the pathologies of a number of retinal degenerative diseases in both the outer and inner retina. In the outer retina, photoreceptors are particularly vulnerable to mutations affecti
Externí odkaz:
https://doaj.org/article/86e23958dde9462c9e095325aaa44ae2
Publikováno v:
PLoS ONE, Vol 9, Iss 1, p e83686 (2014)
Retinal ganglion cells (RGCs) play important roles in retinogenesis. They are required for normal retinal histogenesis and retinal cell number balance. Developmental RGC loss is typically characterized by initial retinal neuronal number imbalance and
Externí odkaz:
https://doaj.org/article/f31fe9a069f94eb282a10751f8e2bbac
Autor:
Winnie Xu, Daniel Kargilis, Sun M. Kim, David Gelston, Samir Reddy, Dev Gupta, Samantha Turner, Tong Lyu, Enrie Gan, Kevin Song, Lauren Rodio, Abigail Manion, Charis Ma, Nima Missaghian, Jerry Cai, Rashini Jayaratne, Anna Feng, Vikram Balasubramanian, Samantha Brosler, James Parente, Uchechi Nwogwugwu, Shivani Guha, Jack Wragan, Anjali Gupta, Yuanyuan Chen, Ashley Terry, Anh D. Le, Steven W. Wang, Chamith Rajapakse
Publikováno v:
Journal of Oral and Maxillofacial Surgery. 80:S28-S29
Publikováno v:
Journal of Oral and Maxillofacial Surgery. 80:S37
Autor:
Chai An Mao, William H. Klein, Takae Kiyama, Zhenlin Ju, Jing Wang, Ching-Kang Chen, Shinako Takada, Steven W. Wang, Ping Pan
Publikováno v:
Molecular Neurodegeneration
Molecular Neurodegeneration, Vol 13, Iss 1, Pp 1-23 (2018)
Molecular Neurodegeneration, Vol 13, Iss 1, Pp 1-23 (2018)
Background Mitochondrial dysfunction has been implicated in the pathologies of a number of retinal degenerative diseases in both the outer and inner retina. In the outer retina, photoreceptors are particularly vulnerable to mutations affecting mitoch
Autor:
Ken Chen, Yongsheng Li, Christopher P. Vellano, Chaoyang Sun, Kang Jin Jeong, Mark J. O'Connor, Shiaw Yih Lin, Zhiyong Ding, Timothy A. Yap, Imelda Mercado-Uribe, Steven W. Wang, Jinsong Liu, Gordon B. Mills, Nidhi Sahni, Xiaohua Chen, Marilyne Labrie, Jiyong Liang, Daniel J. McGrail, Tae-Beom Kim, Hui Dai, Zhenlin Ju, Yiling Lu, Yong Fang, Sanghoon Lee, Dong Zhang, Shannon N. Westin, Guang Peng
Publikováno v:
Cancer cell. 35(6)
We demonstrate that concurrent administration of poly(ADP-ribose) polymerase (PARP) and WEE1 inhibitors is effective in inhibiting tumor growth but poorly tolerated. Concurrent treatment with PARP and WEE1 inhibitors induces replication stress, DNA d
Autor:
Steven W. Wang, Satchidananda Panda, Takae Kiyama, Zhijing Zhang, Chai An Mao, Samer Hattar, Stephen L. Mills, Hongyan Li, Christophe P. Ribelayga
Publikováno v:
The Journal of Neuroscience. 34:13083-13095
Opsin 4 (Opn4)/melanopsin-expressing intrinsically photosensitive retinal ganglion cells (ipRGCs) play a major role in non-image-forming visual system. Although advances have been made in understanding their morphological features and functions, the
Publikováno v:
Experimental Eye Research. 88:542-552
Despite the magnitude of the problem, no effective treatments exist to prevent retinal ganglion cell (RGC) death and optic nerve degeneration from occurring in diseases affecting the human eye. Animal models currently available for developing treatme
Publikováno v:
Developmental Biology. 320(1):175-184
The mesendoderm (ME) cells are the two most vegetal blastomeres in the early developing embryo of the marine shrimp Sicyonia ingentis. These two cells enter mitotic arrest for three cycles after the 5th cell cycle (32-cell stage) and ingress into the
Publikováno v:
Neuron. 43:475-485
In Brn3b(-/-) mice, where 80% of retinal ganglion cells degenerate early in development, the remaining 20% include most or all ganglion cell types. Cells of the same type cover the retinal surface evenly but tile it incompletely, indicating that a re