Zobrazeno 1 - 10
of 13
pro vyhledávání: '"Steven W Sowa"'
Publikováno v:
PLoS Computational Biology, Vol 10, Iss 6, p e1003658 (2014)
Methods for improving microbial strains for metabolite production remain the subject of constant research. Traditionally, metabolic tuning has been mostly limited to knockouts or overexpression of pathway genes and regulators. In this paper, we estab
Externí odkaz:
https://doaj.org/article/0e9ed7d48e8b48fcbbc5ec235961553d
Autor:
Steven W. Sowa, Yueming Qian, Kathryn L. Aron, Ping Xu, Erik Langsdorf, Bethanne Warrack, Nelly Aranibar, Gabi Tremml, Jianlin Xu, Duncan McVey, Michael Reily, Anurag Khetan, Michael C. Borys, Zheng Jian Li
Publikováno v:
Data in Brief, Vol 33, Iss , Pp 106591- (2020)
In this article, we provide four data sets for an industrial Chinese Hamster Ovary (CHO) cell line producing antibodies during a 14-day bioreactor run. This cell line was selected for further evaluation because of its significant titer loss as the ce
Externí odkaz:
https://doaj.org/article/542fd1b1e063445a8be941eb848a5c5d
Autor:
Grace Yao, Steven W. Sowa, Zheng Jian Li, Joon Chong Yee, Michael C. Borys, Jun Tian, Matthew S. Rehmann, Kathryn L. Aron
Publikováno v:
Current Opinion in Chemical Engineering. 22:34-41
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::b4f9983ddc116d84962d9939a382ef1c
https://doi.org/10.1016/j.coche.2018.09.002
https://doi.org/10.1016/j.coche.2018.09.002
Autor:
Ping Xu, Michael C. Borys, Duncan McVey, Kathryn L. Aron, Michael D. Reily, Zheng Jian Li, Yueming Qian, Gabi Tremml, Nelly Aranibar, Anurag Khetan, Erik Langsdorf, Bethanne M. Warrack, Jianlin Xu, Steven W. Sowa
Publikováno v:
Biochemical Engineering Journal. 164:107799
Cell line instability can pose a challenge from both regulatory and business needs perspectives. The regulatory guidelines of International Conference on Harmonization require manufacturers to evaluate the cell substrate with respect to the consisten
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::5017ef63073db62b02f0d5d13a5fa3b2
https://doi.org/10.1016/j.bej.2020.107799
https://doi.org/10.1016/j.bej.2020.107799
Autor:
Gabi Tremml, Duncan McVey, Michael D. Reily, Ping Xu, Anurag Khetan, Erik Langsdorf, Steven W. Sowa, Michael C. Borys, Bethanne M. Warrack, Nelly Aranibar, Jianlin Xu, Kathryn L. Aron, Zheng Jian Li, Yueming Qian
Publikováno v:
Data in Brief, Vol 33, Iss, Pp 106591-(2020)
Data in Brief
Data in Brief
In this article, we provide four data sets for an industrial Chinese Hamster Ovary (CHO) cell line producing antibodies during a 14-day bioreactor run. This cell line was selected for further evaluation because of its significant titer loss as the ce
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::95d95288d5c08ae39125029e8a1074e0
https://doi.org/10.1016/j.dib.2020.106591
https://doi.org/10.1016/j.dib.2020.106591
Publikováno v:
Current Opinion in Biotechnology. 36:161-167
As bioengineering applications expand, the need to design and implement circuits that exhibit dynamic properties increases. In particular, schemes that control precise patterns of gene expression as a function of time are essential for balancing mult
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::87ea76198ef55ce9e4086b0c0ac8565c
https://doi.org/10.1016/j.copbio.2015.08.020
https://doi.org/10.1016/j.copbio.2015.08.020
Autor:
Grant Gelderman, Alex Moon-Walker, Abigail N. Leistra, Steven W. Sowa, Lydia M. Contreras, Howard M. Salis
Publikováno v:
Scientific Reports
Scientific Reports, Vol 8, Iss 1, Pp 1-19 (2018)
Scientific Reports, Vol 8, Iss 1, Pp 1-19 (2018)
Bacterial global post-transcriptional regulators execute hundreds of interactions with targets that display varying molecular features while retaining specificity. Herein, we develop, validate, and apply a biophysical, statistical thermodynamic model
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d774487fef38d89aafce331dbff44232
https://pubmed.ncbi.nlm.nih.gov/29967470
https://pubmed.ncbi.nlm.nih.gov/29967470
Autor:
Desiree DeMille, Tacie D. Hall, Jordan T. Mackay, John T. Prince, Andrew D. Mathis, Benjamin T. Bikman, Julianne H. Grose, Steven W. Sowa
Publikováno v:
Molecular Biology of the Cell
PAS kinase is a conserved sensory protein kinase required for glucose homeostasis. The interactome for yeast PAS kinase 1 (Psk1) is identified, revealing 93 binding partners. Evidence is provided for in vivo phosphorylation of Cbf1 and subsequent inh
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8f5875d21572678eaf8ec3c79a44b198
https://doi.org/10.1091/mbc.e13-10-0631
https://doi.org/10.1091/mbc.e13-10-0631
Integrative FourD omics approach profiles the target network of the carbon storage regulatory system
Autor:
Sarah Lipp, Abigail N. Leistra, Lydia M. Contreras, Steven W. Sowa, Aishwarya Buvanendiran, Tony Romeo, Grant Gelderman, Christopher A. Vakulskas, Areen Pitaktong, Michael Baldea
Publikováno v:
Nucleic Acids Research
Multi-target regulators represent a largely untapped area for metabolic engineering and anti-bacterial development. These regulators are complex to characterize because they often act at multiple levels, affecting proteins, transcripts and metabolite
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5bc72b0adf28118b9cdb8d8b5f8b3d84
https://pubmed.ncbi.nlm.nih.gov/28126921
https://pubmed.ncbi.nlm.nih.gov/28126921
Publikováno v:
Genome Announcements
We report the complete nucleotide sequence of Anabaena sp. 4-3, an efficient producer of sucrose. It was isolated from salt flats near the University of Texas Marine Science Institute in Port Aransas, Texas. The genome may provide insight into the ut
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e58a0dbc79aa8daaab897a5ae15e1e62
https://doi.org/10.1128/genomea.00842-16
https://doi.org/10.1128/genomea.00842-16