Zobrazeno 1 - 10
of 63
pro vyhledávání: '"Steven W Kerrigan"'
Publikováno v:
PLoS ONE, Vol 16, Iss 6, p e0253347 (2021)
The unprecedented global COVID-19 pandemic has prompted a desperate international effort to accelerate the development of anti-viral candidates. For unknown reasons, COVID-19 infections are associated with adverse cardiovascular complications, implic
Externí odkaz:
https://doaj.org/article/22f0b335412e4b908a99c2a5f2a428da
Publikováno v:
PLoS ONE, Vol 7, Iss 7, p e40586 (2012)
Staphylococcus aureus is the most frequent causative organism of osteomyelitis. It is characterised by widespread bone loss and bone destruction. Previously we demonstrated that S. aureus protein A (SpA) is capable of binding to tumour necrosis facto
Externí odkaz:
https://doaj.org/article/ebedb9cbbe374379b37bffde1c9826c4
Autor:
Tania Claro, Amro Widaa, Maghnus O'Seaghdha, Helen Miajlovic, Timothy J Foster, Fergal J O'Brien, Steven W Kerrigan
Publikováno v:
PLoS ONE, Vol 6, Iss 4, p e18748 (2011)
Osteomyelitis is a debilitating infectious disease of the bone. It is predominantly caused by S. aureus and is associated with significant morbidity and mortality. It is characterised by weakened bones associated with progressive bone loss. Currently
Externí odkaz:
https://doaj.org/article/e0f20c27612e4f7f89ff5e9e12362900
Publikováno v:
Pathogens, Vol 4, Iss 4, Pp 869-882 (2015)
Staphylococcus aureus is an opportunistic pathogen often carried asymptomatically on the human body. Upon entry to the otherwise sterile environment of the cardiovascular system, S. aureus can lead to serious complications resulting in organ failure
Externí odkaz:
https://doaj.org/article/021f9e9505c343d0aab77cfdcfc09d05
Autor:
Glenn, Fitzpatrick, Danielle, Nader, Rebecca, Watkin, Claire E, McCoy, Gerard F, Curley, Steven W, Kerrigan
Publikováno v:
Frontiers in Cellular and Infection Microbiology. 12
The pathophysiology of sepsis and its accompanying hyper-inflammatory response are key events that lead to multi-organ failure and death. A growing body of literature now suggests that the vascular endothelium plays a critical role in driving early e
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::96f29c7468db98fe6f03f2f9fce08938
https://doi.org/10.3389/fcimb.2022.854126
https://doi.org/10.3389/fcimb.2022.854126
Autor:
Gerard F. Curley, Steven W. Kerrigan, Mirjana Jerkic, Grace Hogan, John G. Laffey, Glenn Fitzpatrick, Wolfgang M. Kuebler, Claire Masterson, Arata Tabuchi
Publikováno v:
Scientific Reports, Vol 11, Iss 1, Pp 1-12 (2021)
Scientific Reports
Scientific Reports
Mesenchymal stem/stromal cells (MSCs) have demonstrated efficacy in pre-clinical models of inflammation and tissue injury, including in models of lung injury and infection. Rolling, adhesion and transmigration of MSCs appears to play a role during MS
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::395dbaf5d60e0c4a63bf8208aa24ecdd
https://doaj.org/article/79bc632af6ef4beaa0c8151bdb5bc75e
https://doaj.org/article/79bc632af6ef4beaa0c8151bdb5bc75e
Autor:
Pierre Mangin, Mikhail A. Panteleev, Netanel Korin, Wilbur A. Lam, Steven W. Kerrigan, Subcommittee On Biorheology, Keith B. Neeves, Judith M.E.M. Cosemans
Publikováno v:
Journal of Thrombosis and Haemostasis, 19(2), 582-587. Wiley
In vitro flow-based assays are widely used to investigate the role of platelets and coagulation in hemostasis and thrombosis. Their main advantage over other assays relies on the fact that they integrate blood flow that regulates many aspects of plat
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::25256e53c36b594a276c9f1a552d211f
https://doi.org/10.1111/jth.15143
https://doi.org/10.1111/jth.15143
Autor:
Danielle Nader, Timothy E. Gressett, Md Lokman Hossen, Prem Chapagain, Steven W. Kerrigan, Gregory Bix
SummaryIn addition to the ACE2 receptor, SARS-CoV-2 binds to integrins to gain host cell entry and trigger pro-inflammatory integrin-mediated signalling cascades. Integrins, therefore, are likely candidates for a dual-receptor mechanism with ACE2 to
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::ff14616baf18a34926684f26a17301a8
https://doi.org/10.1101/2022.01.02.474028
https://doi.org/10.1101/2022.01.02.474028
Autor:
Gianpiero L. Cavalleri, Steven W. Kerrigan, Tracy Robson, Judith Strawbridge, Michelle Flood, Fiona O'Brien, Róisín Reynolds, Shane Cullinan, Orna Tighe, Brian P. Kirby, Anne Teresa Morgan, John C. Hayden, James W. Barlow, Anthony Maher, Matthew Lynch
Publikováno v:
Research in Social & Administrative Pharmacy
The impact of the COVID-19 pandemic on pharmacy education worldwide has been immense, affecting students, educators and regulatory agencies. Pharmacy programmes have had to rapidly adapt in their delivery of education, maintaining standards while als
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ceba54a4c14a8543536ca7ea9529a4db
http://europepmc.org/articles/PMC8367658
http://europepmc.org/articles/PMC8367658
Publikováno v:
Antibiotics
Volume 10
Issue 5
Antibiotics, Vol 10, Iss 581, p 581 (2021)
Volume 10
Issue 5
Antibiotics, Vol 10, Iss 581, p 581 (2021)
The bacterial pathogen Staphylococcus aureus is a leading cause of bloodstream infections, where patients often suffer from relapse despite antibiotic therapy. Traditional anti-staphylococcal drugs display reduced effectivity against internalised bac
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::317b1ef79fffec956e85977456a50fb8