Výsledky vyhledávání - "Steven W James"

A reciprocal translocation involving Aspergillus nidulans snxAHrb1/Gbp2 and gyfA uncovers a new regulator of the G2–M transition and reveals a role in transcriptional repression for the setBSet2 histone H3-lysine-36 methyltransferase

Autor: Steven W James, Jonathan Palmer, Nancy P Keller, Morgan L Brown, Matthew R Dunworth, Sarah G Francisco, Katherine G Watson, Breanna Titchen, Alecia Achimovich, Andrew Mahoney, Joseph P Artemiou, Kyra G Buettner, Madelyn Class, Andrew L Sydenstricker, Sarah Lea Anglin

Publikováno v: Genetics. 222

Aspergillus nidulans snxA, an ortholog of Saccharomyces cerevisiae Hrb1/Gbp2 messenger RNA shuttle proteins, is—in contrast to budding yeast—involved in cell cycle regulation, in which snxA1 and snxA2 mutations as well as a snxA deletion specific

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7930f900e18e8c63c08f33fb85dfeb7b
https://doi.org/10.1093/genetics/iyac130

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Proteolysis and Tyrosine Phosphorylation of p34 /Cyclin B

Autor: Alice Tang, Kimberly K. McNeal, Kevin B. Ryan, Adam N. Wexler, Russell R. Fincher, Stephen A. Osmani, Scott E. Gygax, Steven W. James, Xiang S. Ye

Publikováno v: Journal of Biological Chemistry. 272:33384-33393

Previously, it has been shown that Aspergillus cells lacking the function of nimQand the anaphase-promoting complex (APC) component bimE APC1 enter mitosis without replicating DNA. Here nimQ is shown to encode an MCM2 homologue. Although mutation of

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::4d208f8b1a244d9c98a1039dc829eb96
https://doi.org/10.1074/jbc.272.52.33384

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nimO, an Aspergillus gene related to budding yeast Dbf4, is required for DNA synthesis and mitotic checkpoint control

Autor: K.A. Bullock, K.A. Prasauckas, H.M. Tobin, Peter C. Scacheri, S.D. Wade, K.K. McNeal, S.E. Gygax, Steven W. James, Bryan A. Kraynack, R.A. Matura, J.A. MacLeod, H.L. Shenefiel

Publikováno v: Journal of cell science. 112

The nimO predicted protein of Aspergillus nidulans is related structurally and functionally to Dbf4p, the regulatory subunit of Cdc7p kinase in budding yeast. nimOp and Dbf4p are most similar in their C-termini, which contain a PEST motif and a novel

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4007a8afb48124aab4d15528227e5deb
https://pubmed.ncbi.nlm.nih.gov/10194410

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A mutation in the alpha 1-tubulin gene of Chlamydomonas reinhardtii confers resistance to anti-microtubule herbicides

Autor: Steven W. James, Paul A. Lefebvre, Carolyn D. Silflow, Pamela Stroom

Publikováno v: Journal of cell science. 106

A mutation in the alpha 1-tubulin gene of Chlamydomonas reinhardtii was isolated by using the amiprophos-methyl-resistant mutation apm1-18 as a background to select new mutants that showed increased resistance to the drug. The upA12 mutation caused t

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8b47c116edd198ed7bd75e72c204593b
https://pubmed.ncbi.nlm.nih.gov/7903670

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Genetic interactions among Chlamydomonas reinhardtii mutations that confer resistance to anti-microtubule herbicides

Autor: Paul A. Lefebvre, Steven W. James

Publikováno v: Genetics. 130(2)

We previously described two types of genetic interactions among recessive mutations in the APM1 and APM2 loci of Chlamydomonas reinhardtii that may reflect a physical association of the gene products or their involvement in a common structure/process

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bab5cc3b62b1bf107f943c743bbb5d84
https://pubmed.ncbi.nlm.nih.gov/1311696

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Mutants resistant to anti-microtubule herbicides map to a locus on the uni linkage group in Chlamydomonas reinhardtii

Autor: Paul A. Lefebvre, Carolyn D. Silflow, Laura P.W. Ranum, Steven W. James

Publikováno v: Genetics. 118:141-147

We have used genetic analysis to study the mode of action of two anti-microtubule herbicides, amiprophos-methyl (APM) and oryzalin (ORY). Over 200 resistant mutants were selected by growth on APM- or ORY-containing plates. The 21 independently isolat

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b1ce19d8152e4bad629dba7f0090cb69
https://doi.org/10.1093/genetics/118.1.141

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Isolation and characterization of dominant, pleiotropic drug-resistance mutants in Chlamydomonas reinhardtii

Autor: Steven W. James, Paul A. Lefebvre

Publikováno v: Current genetics. 15(6)

Three independent pleiotropic drug-resistance (pdr) mutants were isolated by selecting for resistance to the anti-microtubule herbicides amiprophos-methyl (APM) and oryzalin (ORY). These three mutants and a previously isolated mutant, ani1 (anisomyci

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4f5cad0622945315dd86c23f2eeda4ac
https://pubmed.ncbi.nlm.nih.gov/2776231

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Extragenic suppression and synthetic lethality among Chlamydomonas reinhardtii mutants resistant to anti-microtubule drugs

Autor: Laura P.W. Ranum, Paul A. Lefebvre, Michael D. Thompson, Carolyn D. Silflow, Steven W. James

Publikováno v: Genetics. 122(3)

The antimicrotubule agents oryzalin (ORY), colchicine (COL) and taxol (TAX) were used to select three recessive, conditional lethal (ts-) mutants which defined two new essential loci, ory1 and cor1. The two ory1 mutants conferred resistance to ORY, T

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::73d2dbdceba9a9a14a6cef2f92bcdfe1
https://pubmed.ncbi.nlm.nih.gov/2569432

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