Zobrazeno 1 - 10
of 187
pro vyhledávání: '"Steven W, Dow"'
Autor:
Andres F. Bonilla, Katie J. Sikes, Lindsey H. Burton, Lyndah Chow, Jade Kurihara, Kelly Santangelo, Steven W. Dow, Jeremiah T. Easley
Publikováno v:
Frontiers in Veterinary Science, Vol 11 (2024)
Low back pain poses a significant societal burden, with progressive intervertebral disc degeneration (IDD) emerging as a pivotal contributor to chronic pain. Improved animal models of progressive IDD are needed to comprehensively investigate new diag
Externí odkaz:
https://doaj.org/article/accf3cfb1c6b42c5bfe0212c23a6cbd2
Autor:
Jennifer M. Cassano, Brian C. Leonard, Bianca C. Martins, Natalia Vapniarsky, Joshua T. Morgan, Steven W. Dow, Kathryn L. Wotman, Lynn M. Pezzanite
Publikováno v:
Frontiers in Veterinary Science, Vol 10 (2023)
IntroductionEquine recurrent uveitis (ERU), an immune mediated disease characterized by repeated episodes of intra-ocular inflammation, affects 25% of horses in the USA and is the most common cause of glaucoma, cataracts, and blindness. Mesenchymal s
Externí odkaz:
https://doaj.org/article/0252252328f74913b99f500e42780664
Publikováno v:
Veterinary Sciences, Vol 9, Iss 11, p 610 (2022)
Antimicrobial resistance and biofilm formation both present challenges to treatment of bacterial infections with conventional antibiotic therapy and serve as the impetus for development of improved therapeutic approaches. Mesenchymal stromal cell (MS
Externí odkaz:
https://doaj.org/article/f6468810d9e54442836d7432139257d3
Autor:
Maryam F. Afzali, Stephen C. Pannone, Richard B. Martinez, Margaret A. Campbell, Joseph L. Sanford, Lynn M. Pezzanite, Jade Kurihara, Valerie Johnson, Steven W. Dow, Kelly S. Santangelo
Publikováno v:
Journal of Orthopaedic Research. 41:902-912
Osteoarthritis (OA) is a leading cause of morbidity among aging populations, yet symptom and/or disease-modification remains elusive. Adipose-derived mesenchymal stromal cells (adMSCs) have demonstrated immunomodulatory and anti-inflammatory properti
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::214e123b51312741d7b2c4f56ccde302
https://doi.org/10.1002/jor.25431
https://doi.org/10.1002/jor.25431
Supplemental Figure S2. PD-L1 antibody treatment of human macrophages results in phenotypic changes consistent with those seen in murine macrophages. Macrophages were treated with medium only, an irrelevant isotype antibody, or PD-L1 antibody for 6 d
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9423f37ba087164a8b8228878a5bafde
https://doi.org/10.1158/2326-6066.22536440.v1
https://doi.org/10.1158/2326-6066.22536440.v1
Legends for supplemental figures
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1b62bae4608bc831f62c16074b9ea684
https://doi.org/10.1158/2326-6066.22536422.v1
https://doi.org/10.1158/2326-6066.22536422.v1
Tumor-associated macrophages (TAMs) express programmed cell death ligand 1 (PD-L1) and contribute to the immune-suppressive tumor microenvironment. Although the role of the PD-L1 and PD-1 interaction to regulate T-cell suppression is established, les
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::80ead8729cf0ce68088c7b62569c90ae
https://doi.org/10.1158/2326-6066.c.6548141.v1
https://doi.org/10.1158/2326-6066.c.6548141.v1
Autor:
Steven W. Dow, Daniel L. Gustafson, Douglas H. Thamm, Alissa Mathias, Jonathan W. Coy, Jade N. Kurihara, Eric Palmer, Laurel Haines, Sunetra Das, Lyndah Chow, Daniel P. Regan
Supplementary Figure from Losartan Blocks Osteosarcoma-Elicited Monocyte Recruitment, and Combined With the Kinase Inhibitor Toceranib, Exerts Significant Clinical Benefit in Canine Metastatic Osteosarcoma
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3d807ca58bf44c43bbc76a212773e459
https://doi.org/10.1158/1078-0432.22483637
https://doi.org/10.1158/1078-0432.22483637
Autor:
Steven W. Dow, Daniel L. Gustafson, Douglas H. Thamm, Alissa Mathias, Jonathan W. Coy, Jade N. Kurihara, Eric Palmer, Laurel Haines, Sunetra Das, Lyndah Chow, Daniel P. Regan
Purpose:There is increasing recognition that progress in immuno-oncology could be accelerated by evaluating immune-based therapies in dogs with spontaneous cancers. Osteosarcoma (OS) is one tumor for which limited clinical benefit has been observed w
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::17458fd31a5e243205157d79fe3f1565
https://doi.org/10.1158/1078-0432.c.6531188.v1
https://doi.org/10.1158/1078-0432.c.6531188.v1
Autor:
Steven W. Dow, Daniel L. Gustafson, Douglas H. Thamm, Alissa Mathias, Jonathan W. Coy, Jade N. Kurihara, Eric Palmer, Laurel Haines, Sunetra Das, Lyndah Chow, Daniel P. Regan
Supplementary Table from Losartan Blocks Osteosarcoma-Elicited Monocyte Recruitment, and Combined With the Kinase Inhibitor Toceranib, Exerts Significant Clinical Benefit in Canine Metastatic Osteosarcoma
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::452f64a441ff084f4177f88b33ce2506
https://doi.org/10.1158/1078-0432.22483634
https://doi.org/10.1158/1078-0432.22483634