Zobrazeno 1 - 4
of 4
pro vyhledávání: '"Steven V Molinski"'
Autor:
Steven V Molinski, Saumel Ahmadi, Wan Ip, Hong Ouyang, Adriana Villella, John P Miller, Po‐Shun Lee, Kethika Kulleperuma, Kai Du, Michelle Di Paola, Paul DW Eckford, Onofrio Laselva, Ling Jun Huan, Leigh Wellhauser, Ellen Li, Peter N Ray, Régis Pomès, Theo J Moraes, Tanja Gonska, Felix Ratjen, Christine E Bear
Publikováno v:
EMBO Molecular Medicine, Vol 9, Iss 9, Pp 1224-1243 (2017)
Abstract The combination therapy of lumacaftor and ivacaftor (Orkambi®) is approved for patients bearing the major cystic fibrosis (CF) mutation: ΔF508. It has been predicted that Orkambi® could treat patients with rarer mutations of similar “th
Externí odkaz:
https://doaj.org/article/63e4048262714fd991511c4196c2fb6d
Autor:
Saumel Ahmadi, Zoltan Bozoky, Michelle Di Paola, Sunny Xia, Canhui Li, Amy P. Wong, Leigh Wellhauser, Steven V. Molinski, Wan Ip, Hong Ouyang, Julie Avolio, Julie D. Forman-Kay, Felix Ratjen, Jeremy A. Hirota, Johanna Rommens, Janet Rossant, Tanja Gonska, Theo J. Moraes, Christine E. Bear
Publikováno v:
npj Genomic Medicine, Vol 2, Iss 1, Pp 1-10 (2017)
Cystic fibrosis: toward personalized therapies A new method for evaluating drug responses in patient-derived respiratory tissue promises to help determine the best treatment for each patient with cystic fibrosis (CF). CF patients are highly susceptib
Externí odkaz:
https://doaj.org/article/7ad6ed4d84964bd982f178ae435366d1
Autor:
J. Javier Hernandez, Michael Pryszlak, Lindsay Smith, Connor Yanchus, Naheed Kurji, Vijay M. Shahani, Steven V. Molinski
Publikováno v:
Frontiers in Oncology, Vol 7 (2017)
The repositioning or “repurposing” of existing therapies for alternative disease indications is an attractive approach that can save significant investments of time and money during drug development. For cancer indications, the primary goal of re
Externí odkaz:
https://doaj.org/article/d0fd9d77c9ce4c72a6ca6c16b6a7145f
Autor:
Steven V. Molinski, Vijay M. Shahani, Adithya S. Subramanian, Stephen S. MacKinnon, Geoffrey Woollard, Marcon Laforet, Onofrio Laselva, Leonard D. Morayniss, Christine E. Bear, Andreas Windemuth
Publikováno v:
Proteins: Structure, Function, and Bioinformatics. 86:C1-C1