Zobrazeno 1 - 10
of 29
pro vyhledávání: '"Steven T. Poole"'
Autor:
Shiqi Zhou, Karl O.A. Yu, Moustafa T. Mabrouk, Dushyant Jahagirdar, Wei-Chiao Huang, Julio A. Guerra, Xuedan He, Joaquin Ortega, Steven T. Poole, Eric R. Hall, Oscar G. Gomez-Duarte, Milton Maciel, Jr., Jonathan F. Lovell
Publikováno v:
Biomedical Journal, Vol 46, Iss 6, Pp 100588- (2023)
Background: Enterotoxigenic Escherichia coli (ETEC) strains cause infectious diarrhea and colonize host intestine epithelia via surface-expressed colonization factors. Colonization factor antigen I (CFA/I), a prevalent ETEC colonization factor, is a
Externí odkaz:
https://doaj.org/article/ff69563edaf3491ea5971bdac0a3cd29
Autor:
Kawsar R. Talaat, Chad K. Porter, Subhra Chakraborty, Brittany L. Feijoo, Jessica Brubaker, Brittany M. Adjoodani, Barbara DeNearing, Michael G. Prouty, Steven T. Poole, A. Louis Bourgeois, Madison Billingsley, David A. Sack, Susanne Eder-Lingelbach, Christian Taucher
Publikováno v:
Microorganisms, Vol 12, Iss 4, p 727 (2024)
Controlled human infection models are important tools for the evaluation of vaccines against diseases where an appropriate correlate of protection has not been identified. Enterotoxigenic Escherichia coli (ETEC) strain LSN03-016011/A (LSN03) is an LT
Externí odkaz:
https://doaj.org/article/5f3a34f3ebdc48288a3296a738ed5782
Autor:
Ramiro L. Gutiérrez, Mark S. Riddle, Chad K. Porter, Milton Maciel, Steven T. Poole, Renee M. Laird, Michelle Lane, George W. Turiansky, Abel Jarell, Stephen J. Savarino
Publikováno v:
Microorganisms, Vol 11, Iss 11, p 2689 (2023)
Introduction: Enterotoxigenic E. coli (ETEC) is a leading cause of diarrhea in travelers as well as for children living in low- to middle-income countries. ETEC adhere to intestinal epithelium via colonization factors (CFs). CFA/I, a common CF, is co
Externí odkaz:
https://doaj.org/article/fe6b9f7b367f45e58abf63f09712be27
Autor:
Yang Liu, Milton Maciel, Aisling O’Dowd, Steven T. Poole, Julianne E. Rollenhagen, Irina V. Etobayeva, Stephen J. Savarino
Publikováno v:
Microorganisms, Vol 9, Iss 8, p 1646 (2021)
Enterotoxigenic Escherichia coli (ETEC) is a leading cause of diarrhea in travelers and children in resource-limited countries. ETEC colonization factors, fimbrial tip adhesins and enterotoxins are key virulence factors, and thus have been studied as
Externí odkaz:
https://doaj.org/article/6aac80f5dd714a7da271b88979421de2
Autor:
Nereyda Espinoza, S. S. Joseph, M.P. Simons, Annette L. McVeigh, Stephen J. Savarino, N.D. Reynolds, Julianne E. Rollenhagen, Milton Maciel, R. Castillo, David Poncet, Michael G. Prouty, Jon Heinrichs, Steven T. Poole, M. Nieto, Gladys Nunez, Geneviève Renauld-Mongénie, Amritha Ramakrishnan, J.M. Royal
Publikováno v:
Vaccine. 39:487-494
Colonization factors or Coli surface antigens (CFs or CS) are important virulence factors of Enterotoxigenic E. coli (ETEC) that mediate intestinal colonization and accordingly are targets of vaccine development efforts. CS6 is a highly prevalent CF
Autor:
Stephen J. Savarino, Michael G. Prouty, Julianne E. Rollenhagen, Greg Glenn, Larry Ellingsworth, Jing Hui Tian, Steven T. Poole, Colleen M. Woods, Mimi Guebre-Xabier, Aisling O’Dowd
Publikováno v:
Vaccine. 37:6134-6138
dscCfaE is a recombinant form of the CFA/I tip adhesin CfaE, expressed by a large proportion of enterotoxigenic E. coli (ETEC). It is highly immunogenic by the intranasal route in mice and Aotus nancymaae, protective against challenge with CFA/I+ ETE
Autor:
Ramiro L. Gutierrez, Alison Lane, Christopher A. Duplessis, Michael G. Prouty, Steven T. Poole, Nicole Maier, Tida Lee, Milton Maciel, Melinda Hamer, Stefanie Trop, Ashley Alcala, A. Louis Bourgeois, Chad K. Porter, Rahsan Erdem, Kayla J. Testa, Mark S. Riddle
Publikováno v:
Vaccine
Introduction Enterotoxigenic Escherichia coli (ETEC) is a common cause of infectious diarrhoea and a leading cause of morbidity and mortality in children living in resource-limited settings. It is also the leading cause of travellers’ diarrhoea amo
Autor:
Chad K. Porter, David R. Tribble, Barbara DeNearing, Stephen J. Savarino, Robin McKenzie, Shannon L. Grahek, Aisling O'Dowd, Stephanie A. Sincock, Carl Brinkley, Steven T. Poole, Joseph H. Crabb, Colleen M. Woods, A. Louis Bourgeois, Hye Kim
Publikováno v:
The Journal of Infectious Diseases. 220:505-513
BackgroundEnterotoxigenic Escherichia coli (ETEC) commonly cause diarrhea in children living in developing countries and in travelers to those regions. ETEC are characterized by colonization factors (CFs) that mediate intestinal adherence. We assesse
Autor:
Steven T. Poole, Yang Liu, Patricia Guerry, Renee M. Laird, Eman Omari, Frédéric Poly, Annette L. McVeigh, Nelum Dorabawila, Kavyashree Satish, Mario A. Monteiro, Milton Maciel, Cheryl P. Ewing, Brittany Pequegnat, Nina M. Schumack, Zuchao Ma, Alexander C. Maue, Christina L. Gariepy, Michael G. Prouty, Stephen J. Savarino
Publikováno v:
Vaccine. 36:6695-6702
Enterotoxigenic Escherichia coli (ETEC), Campylobacter jejuni (CJ), and Shigella sp. are major causes of bacterial diarrhea worldwide, but there are no licensed vaccines against any of these pathogens. Most current approaches to ETEC vaccines are bas
Autor:
Colleen M. Woods, Michael J. Gregory, Stephen J. Savarino, Milton Maciel, Michael G. Prouty, Steven T. Poole, Julianne E. Rollenhagen, Stephanie A. Sincock, Ryan C. Maves, Michael G. Jobling, Randall K. Holmes, Annette L. McVeigh, Aisling O'Dowd
Publikováno v:
Infect Immun
Recent efforts to develop an enterotoxigenic Escherichia coli (ETEC) vaccine have focused on the antigenically conserved tip adhesins of colonization factors. We showed previously that intranasal immunization with dsc(19)CfaE, a soluble variant of th