Zobrazeno 1 - 10
of 137
pro vyhledávání: '"Steven Shak"'
Autor:
Ulrike Nitz, Oleg Gluz, Hans H. Kreipe, Matthias Christgen, Sherko Kuemmel, Frederick L. Baehner, Steven Shak, Bahriye Aktas, Michael Braun, Kerstin Lüdtke-Heckenkamp, Helmut Forstbauer, Eva-Maria Grischke, Benno Nuding, Maren Darsow, Claudia Schumacher, Katja Krauss, Wolfram Malter, Marc Thill, Mathias Warm, Rachel Wuerstlein, Ronald E. Kates, Nadia Harbeck
Publikováno v:
Therapeutic Advances in Medical Oncology, Vol 12 (2020)
Background: Endocrine sensitivity, as determined by response of the proliferation marker Ki-67 to short-term preoperative endocrine therapy (ET), is currently not included in adjuvant treatment decisions in hormone receptor (HR)+/human epidermal grow
Externí odkaz:
https://doaj.org/article/115b004b52414ec081eca0fe5b0d1c40
Autor:
Frédérique Penault-Llorca, Thomas Filleron, Bernard Asselain, Frederick L. Baehner, Pierre Fumoleau, Magali Lacroix-Triki, Joseph M. Anderson, Carl Yoshizawa, Diana B. Cherbavaz, Steven Shak, Lise Roca, Christine Sagan, Jérôme Lemonnier, Anne-Laure Martin, Henri Roché
Publikováno v:
BMC Cancer, Vol 18, Iss 1, Pp 1-10 (2018)
Abstract Background The 21-gene Recurrence Score (RS) result predicts outcome and chemotherapy benefit in node-negative and node-positive (N+), estrogen receptor-positive (ER+) patients treated with endocrine therapy. The purpose of this study was to
Externí odkaz:
https://doaj.org/article/9476d32f54b04292be4c2d9ac5b73b52
Autor:
Corey W. Speers, W. Fraser Symmans, William E. Barlow, Alex Trevarton, Stephanie The, Lili Du, James M. Rae, Steven Shak, Rick Baehner, Priyanka Sharma, Lajos Pusztai, Gabriel N. Hortobagyi, Daniel F. Hayes, Kathy S. Albain, Andrew Godwin, Alastair Thompson
Publikováno v:
Journal of Clinical Oncology. 41:1841-1848
PURPOSE Chemotherapy has not demonstrated benefit over adjuvant endocrine therapy alone for postmenopausal patients with node-positive breast cancer with a 21-gene breast recurrence score (RS) of 25 or below (RS ≤ 25). We tested whether combined re
Autor:
Charles L, Vogel, Melody A, Cobleigh, Debu, Tripathy, John C, Gutheil, Lyndsay N, Harris, Louis, Fehrenbacher, Dennis J, Slamon, Maureen, Murphy, William F, Novotny, Michael, Burchmore, Steven, Shak, Stanford J, Stewart, Michael, Press
Publikováno v:
Journal of Clinical Oncology. 41:1638-1645
PURPOSE To evaluate the efficacy and safety of first-line, single-agent trastuzumab in women with HER2-overexpressing metastatic breast cancer. PATIENTS AND METHODS One hundred fourteen women with HER2-overexpressing metastatic breast cancer were ran
Autor:
Virginia Paton, Gracie Lieberman, Melody A. Cobleigh, Debasish Tripathy, Nicholas J. Robert, Charles L. Vogel, Louis Fehrenbacher, Janet M. Wolter, Steven Shak, Susy Scholl, Dennis J. Slamon
Publikováno v:
Journal of Clinical Oncology. 41:1501-1510
PURPOSE Overexpression of the HER2 protein occurs in 25% to 30% of human breast cancers and leads to a particularly aggressive form of the disease. Efficacy and safety of recombinant humanized anti-HER2 monoclonal antibody as a single agent was evalu
Autor:
Irene Kang, Jamie K. Forschmiedt, Michelle M. Loch, William E. Barlow, Danika L. Lew, Julie R. Gralow, Funda Meric-Bernstam, Kathy S. Albain, Daniel F. Hayes, Nancy U. Lin, Edith A. Perez, Lori J. Goldstein, Priya Rastogi, Anne F. Schott, Steven Shak, Priyanka Sharma, Jieling Miao, Debu Tripathy, Lajos Pusztai, Gabriel N. Hortobagyi, Kevin Kalinsky, N. Lynn Henry
Publikováno v:
Cancer Research. 83:GS1-04
Introduction: Breast cancer treatment is associated with cancer-related cognitive impairment (CRCI). However, the differential effect of endocrine therapy (ET) vs chemotherapy followed by endocrine therapy (CET), including the impact of menopausal st
Autor:
Olga Kantor, Harold J. Burstein, Tari A. King, Steven Shak, Christy A. Russell, Armando E. Giuliano, Gabriel N. Hortobagyi, Eric P. Winer, Larissa A. Korde, Joseph A. Sparano, Elizabeth A. Mittendorf
Publikováno v:
Annals of Surgical Oncology. 29:8016-8023
Autor:
Robert Gray, George W. Sledge, Nancy E. Davidson, Silvana Martino, Lawrence N. Shulman, Edith Perez, Steve Rowley, Roberto Bugarini, Frederick L. Baehner, Sunil Badve, Diana Brassard, Steven Shak, Barrett H. Childs, Lori J. Goldstein, Joseph A. Sparano
Supplementary Data from Relationship between Topoisomerase 2A RNA Expression and Recurrence after Adjuvant Chemotherapy for Breast Cancer
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::18650a49d46adff23b7ba64f40980162
https://doi.org/10.1158/1078-0432.22440490
https://doi.org/10.1158/1078-0432.22440490
Autor:
Robert Gray, George W. Sledge, Paraic A. Kenny, Nancy E. Davidson, Silvana Martino, Lawrence N. Shulman, Edith A. Perez, Steve Rowley, Roberto Bugarini, Frederick L. Baehner, Sunil Badve, Diana Brassard, Steven Shak, Barrett H. Childs, Lori J. Goldstein, Joseph A. Sparano
XLS file - 31K, Patient characteristics by GRB7 expression.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3aca49751437550bb5c121bed149fe42
https://doi.org/10.1158/1078-0432.22444047.v1
https://doi.org/10.1158/1078-0432.22444047.v1
Autor:
Robert Gray, George W. Sledge, Paraic A. Kenny, Nancy E. Davidson, Silvana Martino, Lawrence N. Shulman, Edith A. Perez, Steve Rowley, Roberto Bugarini, Frederick L. Baehner, Sunil Badve, Diana Brassard, Steven Shak, Barrett H. Childs, Lori J. Goldstein, Joseph A. Sparano
PDF file - 72K, Box plots (with center line at the median and box edges at the quartiles) showing the raw distribution of GRB7, ERBB2, KRT19 and PHB expression for the triple negative (TN) subset, hormone receptor negative (HR-), HER2-positive (HER2+
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4cb2edb95da7855efadefd5624c45c08
https://doi.org/10.1158/1078-0432.22444050.v1
https://doi.org/10.1158/1078-0432.22444050.v1