Zobrazeno 1 - 10
of 52
pro vyhledávání: '"Steven S. Matsuyama"'
Publikováno v:
Journal of Neuroscience Research. 52:498-504
Neuron-like cells derived from a rat pheochromocytoma cell line (PC12) and differentiated with nerve growth factor produce a paired helical filament (PHF)-like antigen when they are subjected to heat shock (Wallace et al.: Mol Brain Res 19:149-155, 1
Autor:
D. Norman, Leonard L. Heston, Lissy F. Jarvik, Thomas D. Bird, Robert Katzman, M. A. Head, Jeffrey Kaye, Steven S. Matsuyama, D. Q. McManus, Haydeh Payami, Gerard D. Schellenberg, Bruce L. Miller, Sepideh Zareparsi, Gary W. Small, Gary Sexton
Publikováno v:
Neurology. 49:512-518
Our earlier studies had suggested a possible association between the HLA-A2 allele and Alzheimer's disease (AD). In the present study we tested the hypothesis that A2 is associated with earlier AD onset. We performed two independent studies: a collab
Autor:
Asenath La Rue, Susan McPherson, Lissy F. Jarvik, Scott Komo, Steven S. Matsuyama, Gary W. Small
Publikováno v:
Aging, Neuropsychology, and Cognition. 3:132-140
Self-ratings of everyday memory function and performance on memory tests were examined in 61 first-degree relatives of patients with Alzheimer's disease (AD) and 41 matched controls without a family history of dementia. Subjective memory ratings were
Publikováno v:
International Psychogeriatrics. 7:367-376
This study examined the relationship between subjective memory complaints and performance on tests of memory by relatives of patients with probable Alzheimer's disease (AD) and by older adults without a family history of dementia. Relatives of AD pat
Autor:
Steven S. Matsuyama, William Bondareff
Publikováno v:
International Review of Psychiatry. 7:349-360
SummaryDementia in Alzheimer's disease is associated closely with the accumulation of hyperpkosphorylated, C-terminally truncated tau protein. It is accumulated, in part, into paired helical filaments (PHF) which form the neurofibrillary tangles char
Autor:
William Bondareff, Steven S. Matsuyama
Publikováno v:
Journal of Neuroscience Research. 39:519-524
The presence of the microtubule-associated protein tau in skin fibroblasts derived from Alzheimer patients and normal controls was investigated using a panel of well-characterized anti-tau antibodies against epitopes spanning the tau protein from the
Autor:
Lissy F. Jarvik, Steven S. Matsuyama
Publikováno v:
AGE. 16:152-158
There is increasing evidence that cytoskeletal changes, in particular perturbation of the microtubule (MT) system, play a role in the pathogenesis of Alzheimer disease (AD). The reappearance of the cytoplasmic MT network following treatment with the
Autor:
Steven S. Matsuyama, M. Mandelkern, Robert B. Lufkin, Gary W. Small, Andrew F. Leuchter, Asenath La Rue, William Bondareff, Lissy F. Jarvik, Anna Okonek
Publikováno v:
Archives of Neurology. 50:209-219
• Objective. —The study of monozgotic twins can elucidate possible environmental causes for a disease in genetically identical subjects. To this end, we studied a pair of monozygotic female twins appearing discordant for dementia of the Alzheimer
Autor:
Susan L. Smalley, A LaRue, J.A. Woodward, B H Wolkenstein, Steven S. Matsuyama, Lissy F. Jarvik
Publikováno v:
Genetic Epidemiology. 9:333-345
Dementia of the Alzheimer type (DAT) is a neurodegenerative disorder which afflicts approximately 3% of the population. Genetic influences are indicated from twin and family studies although genetic heterogeneity has been suggested from both pedigree