Zobrazeno 1 - 10
of 13
pro vyhledávání: '"Steven S. Eamegdool"'
Autor:
Adrian Westhaus, Steven S. Eamegdool, Milan Fernando, Paula Fuller-Carter, Alicia A. Brunet, Annie L. Miller, Rabab Rashwan, Maddison Knight, Maciej Daniszewski, Grace E. Lidgerwood, Alice Pébay, Alex Hewitt, Giorgia Santilli, Adrian J. Thrasher, Livia S. Carvalho, Anai Gonzalez-Cordero, Robyn V. Jamieson, Leszek Lisowski
Publikováno v:
Scientific Reports, Vol 13, Iss 1, Pp 1-15 (2023)
Abstract Adeno-associated viral (AAV) vector-mediated retinal gene therapy is an active field of both pre-clinical as well as clinical research. As with other gene therapy clinical targets, novel bioengineered AAV variants developed by directed evolu
Externí odkaz:
https://doaj.org/article/c01c7ea263f948d68832145c2e5bdb19
Autor:
Samuel C. Eggenberger, Natalie L. James, Cherry Ho, Steven S. Eamegdool, Veronika Tatarinoff, Naomi A. Craig, Barry S. Gow, Susan Wan, Christopher W.D. Dodds, Donna La Hood, Aaron Gilmour, Shannon L. Donahoe, Mark Krockenberger, Krishna Tumuluri, Melville J. da Cruz, John R. Grigg, Peter McCluskey, Nigel H. Lovell, Michele C. Madigan, Adrian T. Fung, Gregg J. Suaning
Publikováno v:
Data in Brief, Vol 39, Iss , Pp 107634- (2021)
The data presented here are related and supplementary data to the research article “Implantation and long-term assessment of the stability and biocompatibility of a novel 98 channel suprachoroidal visual prosthesis in sheep” [1]. In Eggenberger e
Externí odkaz:
https://doaj.org/article/63829d9e51c44b09b0e506d4d9a1d8d7
Autor:
Benjamin M. Nash, To Ha Loi, Milan Fernando, Amin Sabri, James Robinson, Anson Cheng, Steven S. Eamegdool, Elizabeth Farnsworth, Bruce Bennetts, John R. Grigg, Seo-Kyung Chung, Anai Gonzalez-Cordero, Robyn V. Jamieson
Publikováno v:
Stem Cells International, Vol 2021 (2021)
Human induced pluripotent stem cells (hiPSCs) generated from patients and the derivative retinal cells enable the investigation of pathological and novel variants in relevant cell populations. Biallelic pathogenic variants in RPE65 cause early-onset
Externí odkaz:
https://doaj.org/article/efc0b3e3faab4cc08d30e555d2e914e1
Publikováno v:
Free Radical Biology and Medicine. 146:357-371
Age-related macular degeneration (AMD), the most common cause of vision loss with ageing, is characterised by degeneration of the photoreceptors and retinal pigment epithelium (RPE) and changes in the extracellular matrix (ECM) underlying the RPE. Th
Autor:
Peter McCluskey, Steven S. Eamegdool, R Max Conway, Ephrem I. Sitiwin, Michele C. Madigan, Adrian V Cioanca, Riccardo Natoli, Chieh-Lin Stanley Wu, Martine J. Jager
Publikováno v:
Pigment Cell and Melanoma Research, 34(5), 928-945. WILEY
The choroid within the human eye contains a rich milieu of cells including melanocytes. Human choroidal melanocytes (HCMs) absorb light, regulate free radical production, and were recently shown to modulate inflammation. This study aimed to identify
Publikováno v:
Experimental Eye Research. 173:73-84
Toll-like receptors (TLRs) are a class of pattern recognition receptors that sense highly conserved pathogen associated antigenic determinants, triggering an innate immune response and subsequently instructing the adaptive immune system so that toget
Autor:
Christopher W.D. Dodds, Cherry Ho, Krishna Tumuluri, Samuel C. Eggenberger, John R. Grigg, Naomi A. Craig, Michele C. Madigan, Gregg J. Suaning, Donna La Hood, Steven S. Eamegdool, Veronika Tatarinoff, Natalie L. James, Mark B. Krockenberger, Melville da Cruz, Susan Wan, Adrian T. Fung, Nigel H. Lovell, Shannon L. Donahoe, Barry S. Gow, Peter McCluskey, Aaron Gilmour
Publikováno v:
Data in Brief
Data in Brief, Vol 39, Iss, Pp 107634-(2021)
Data in Brief, Vol 39, Iss, Pp 107634-(2021)
The data presented here are related and supplementary data to the research article “Implantation and long-term assessment of the stability and biocompatibility of a novel 98 channel suprachoroidal visual prosthesis in sheep” [1] . In Eggenberger
Publikováno v:
Acta Ophthalmologica. 94
Autor:
Steven S. Eamegdool, James S. Wiley, David G. Allen, Tailoi Chan-Ling, Michael D. Lovelace, Ben J. Gu, Michael W. Weible
Publikováno v:
Stem cells (Dayton, Ohio). 33(2)
During early human neurogenesis there is overproduction of neuroblasts and neurons accompanied by widespread programmed cell death (PCD). While it is understood that CD68+ microglia and astrocytes mediate phagocytosis during target-dependent PCD, lit
Autor:
Binh T. T. Pham, Stuart M. Grieve, Steven S. Eamegdool, Tailoi Chan-Ling, Brian S. Hawkett, Michael W. Weible
Publikováno v:
Biomaterials. 35(21)
Stem cells prelabelled with iron oxide nanoparticles can be visualised using magnetic resonance imaging (MRI). This technique allows for noninvasive long-term monitoring of migration, integration and stem cell fate following transplantation into livi