Zobrazeno 1 - 10
of 17
pro vyhledávání: '"Steven S. Bondy"'
Autor:
David A. Oare, I-hung Shih, Laura S. Lehman, Erik De Clercq, Eric Mabery, Steven S. Bondy, Weidong Zhong, Inge Vliegen, Matthew Paulson, Johan Neyts, Gerhard Pürstinger, Hans Reiser, Jan Paeshuyse, Nina Boddeker, Tine De Burghgraeve, William A. Lee
Publikováno v:
Journal of Hepatology
Background/Aims Following lead optimization, a set of substituted imidazopyridines was identified as potent and selective inhibitors of in vitro HCV replication. The particular characteristics of one of the most potent compounds in this series (5-[[3
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::034b0a9d32ab3e902fed4fe6a8554f20
http://europepmc.org/articles/PMC7114863
http://europepmc.org/articles/PMC7114863
Autor:
Maisoun Sulfab, Weidong Zhong, Vivian Randall W, Steven S. Bondy, Wanchi Fung, Hengli Tang, Uli Schmitz, Christy M. Hebner, Johan Neyts, Michelle Nash, Trenkle James D, Magdeleine Hung, Xiaohong Liu, John O. Link, Roman Sakowicz, Yang Tian, Katherine M. Brendza, Kyla Bjornson, James G. Taylor, Bin Han
Publikováno v:
PLoS ONE, Vol 7, Iss 6, p e39163 (2012)
PLoS ONE
PLoS ONE
Tegobuvir (TGV) is a novel non-nucleoside inhibitor (NNI) of HCV RNA replication with demonstrated antiviral activity in patients with genotype 1 chronic HCV infection. The mechanism of action of TGV has not been clearly defined despite the identific
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::37eb239ff3664f9808b15cf1b7dd382f
https://www.ncbi.nlm.nih.gov/pmc/articles/pmid/22720059/pdf/?tool=EBI
https://www.ncbi.nlm.nih.gov/pmc/articles/pmid/22720059/pdf/?tool=EBI
Autor:
Francis Van Middlesworth, Susan A. Warne, Patricia Conard, Meheryar N. Rivetna, Anthony J. Conley, Emilio A. Emini, Richard L. Tolman, John Hannah, Catherine A. Dolan, Steven S. Bondy, Jon A. Rudbach, Victoria K. Rusiecki, J. Terry Ulrich, Stephen Marburg, William J. Leanza, Elizabeth E. Sugg
Publikováno v:
Vaccine. 12:445-451
A successful prophylactic human immunodeficiency virus type 1 (HIV-1) vaccine must elicit an immune response that will prevent establishment of the persistent viral infection. The only response shown to be effective in this regard is virus-neutralizi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::958b2074439a5f0e1bb7ee5bd06f5c44
https://doi.org/10.1016/0264-410x(94)90123-6
https://doi.org/10.1016/0264-410x(94)90123-6
Autor:
Yang Tian, Betty Peng, Weidong Zhong, Matthew Paulson, William A. Lee, Gerhard Pürstinger, Uli Schmitz, I-hung Shih, Johan Neyts, Xiaoping Qi, Tse Winston C, Steven S. Bondy, Huiling Yang, Eric Mabery, Hans Reiser, Laura S. Lehman, Jan Paeshuyse, Inge Vliegen, Martijn Fenaux, Christy M. Hebner, Gina Bahador
Publikováno v:
Antimicrobial agents and chemotherapy. 55(9)
GS-9190 (Tegobuvir) is a novel imidazopyridine inhibitor of hepatitis C virus (HCV) RNA replication in vitro and has demonstrated potent antiviral activity in patients chronically infected with genotype 1 (GT1) HCV. GS-9190 exhibits reduced activity
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2b0c95c10a4eca67ef085c251f5527d5
https://pubmed.ncbi.nlm.nih.gov/21746939
https://pubmed.ncbi.nlm.nih.gov/21746939
The inhibition of C5a receptor binding by analogs of L-156,602, a cyclic hexadepsipeptide antibiotic
Autor:
Sumire V. Kobayashi, Dana N. Cianciarulo, Thomas E. Rollins, Robert A. Zambias, Salvatore J. Siciliano, Charles G. Caldwell, Steven S. Bondy, Joung L. Goulet, Joshua S. Boger, Martin S. Springer, Milton L. Hammond, Philippe L. Durette, Joanne F. Kinneary, William K. Hagmann, Thomas J. Lanza, Ihor E. Kopka
Publikováno v:
Bioorganic & Medicinal Chemistry Letters. 2:1033-1038
The cyclic hexadepsipeptide antibiotic L-156,602 ( 1 ) was found to be an inhibitor of anaphylatoxin C5a binding to its receptor (IC 50 =1.7 μg/mL). This compound also caused nonspecific degranulation of neutrophils, but not through interactions wit
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::6ab7fd99952793faca88df9ad57961a9
https://doi.org/10.1016/s0960-894x(00)80613-7
https://doi.org/10.1016/s0960-894x(00)80613-7
Publikováno v:
The Journal of Organic Chemistry. 55:2355-2361
The 14-carbon tetrahydropyranylpropionic acid side chain of the cyclic hexadepsipeptide antibiotic L-156,602 (1) has been prepared as the methyl ester derivative 5. Asymmetric synthesis of the key intermediate 11-carbon lactone 7 was accomplished usi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::70be3e445879ea4a7d3d93acd100af53
https://doi.org/10.1021/jo00295a023
https://doi.org/10.1021/jo00295a023
Autor:
Peter L. Barker, Thomas J. Lanza, Milton L. Hammond, Florence Baker, Steven S. Bondy, Charles G. Caldwell, Philippe L. Durette, Arsenio A. Pessolano, Joshua S. Boger
Publikováno v:
Tetrahedron Letters. 31:1237-1240
The total synthesis of the naturally occurring cyclic hexadepsipeptide antibiotic L-156,602 ( 1 ) is described.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::f1e15857aba26830746c5f65669b5a5a
https://doi.org/10.1016/s0040-4039(00)88774-2
https://doi.org/10.1016/s0040-4039(00)88774-2
Autor:
I-hung Shih, Gerhard Pürstinger, Johan Neyts, Leen Delang, Inge Vliegen, William A. Lee, Steven S. Bondy, Jan Paeshuyse, Weidong Zhong
Publikováno v:
Journal of Hepatology. 54:S197-S198
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::48e1c5531abb9a1ea9c70d5c76eba8ba
https://doi.org/10.1016/s0168-8278(11)60484-4
https://doi.org/10.1016/s0168-8278(11)60484-4
Autor:
Steven S. Bondy, Charles G. Caldwell
Publikováno v:
Synthesis. 1990:34-36
Both enantiomers of erythro-3-hydroxyleucine are available by asymmetric epoxidation of (E)-4-methyl-2-penten-1-ol (1) followed by ruthenium tetroxide catalyzed oxidation to the corresponding glycidic acid 3, epoxide opening by benzylamine, and hydro
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::36ddd672776460c856863ea807e339ad
https://doi.org/10.1055/s-1990-26779
https://doi.org/10.1055/s-1990-26779
Autor:
Inge Vliegen, Johan Neyts, William A. Lee, Steven S. Bondy, Weidong Zhong, I-hung Shih, Gerhard Pürstinger, Jan Paeshuyse
Publikováno v:
Antiviral Research. 90:A65
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::1c69e44ee235b9f8682e750e35417bcc
https://doi.org/10.1016/j.antiviral.2011.03.131
https://doi.org/10.1016/j.antiviral.2011.03.131