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pro vyhledávání: '"Steven R. Witowski"'
Autor:
Karsten Koppetsch, John C. Amedio, Jonathan E. Scherer, Vincent Jacques, Shirley Kalogeropoulos, Lombardy Richard John, Kevin L. Zhou, Stuart Levy, Steven R. Witowski, Kelly Schumacher
Publikováno v:
Organic Process Research & Development. 13:535-542
A process for the multigram asymmetric synthesis of the chiral tetraazamacrocycle 2-(R)-2-(4,7,10-tris tert-butylcarboxymethyl-1,4,7,10-tetraazacyclododec-1-yl)-pentanedioic acid, 1-tert-butyl ester ((R)-tert-Bu4-DOTAGA, 4) has been devised and demon
Autor:
Rebecca D. Rostand, Jacinth A.M McKenzie, Robert T. Kennedy, Steven R. Witowski, Christopher J. Watson, Igor German
Publikováno v:
Journal of Chromatography A. 962:105-115
A method for the separation and quantitative determination of neuroactive amino acids (aspartate, glutamate, citrulline, arginine, glycine, taurine, gamma-aminobutyric acid) and neuroactive amines (noradrenaline, dopamine and serotonin) in a single c
Autor:
Rebecca R. Rostand, Ziqiang Wang, Christopher J. Watson, William E. Haskins, David H. Powell, Steven R. Witowski, Robert T. Kennedy
Publikováno v:
Analytical Chemistry. 73:5005-5014
Fused-silica capillary LC columns (25-microm i.d.) with 3-microm-i.d. integrated electrospray emitters interfaced to a quadrupole ion trap mass spectrometer were evaluated for high-sensitivity LC-MS2. Column preparation involved constructing frits by
Publikováno v:
Analytical Chemistry. 72:865-871
A sensitive method was developed to determine 16 amino acids, including all the neurotransmitter amino acids and neuromodulators, in physiological samples. Samples were derivatized with o-phthalaldehyde/tert-butyl thiol followed by two scavenging rea
Publikováno v:
Chemical Reviews. 99:3081-3132
Separations are generally considered a slow step in any analytical methodology. HPLC and electrophoresis, the mainstay of separations of nonvolatile compounds in the modern laboratory, take anywhere from tens of minutes to hours to complete depending
Publikováno v:
Analytical Chemistry. 71:987-994
The separation and detection of biuret complexes of neuropeptides by capillary liquid chromatography with electrochemical detection was explored. Capillaries of 25-micron inner diameter packed with base-resistant, polymer-based reversed-phase particl
Publikováno v:
ChemInform. 30
Separations are generally considered a slow step in any analytical methodology. HPLC and electrophoresis, the mainstay of separations of nonvolatile compounds in the modern laboratory, take anywhere from tens of minutes to hours to complete depending
Autor:
Michael I Sandstrom, Steven R. Witowski, George V. Rebec, Rebecca D. Rostand, Robert T. Kennedy
Publikováno v:
Neuroscience letters. 378(3)
To determine if extracellular ascorbate, which may increase by several hundred micromolar in striatum during behavioral activation, directly alters glutamate transmission, we monitored striatal glutamate transients evoked by electrical stimulation of
Autor:
Stuart G. Levy, Vincent Jacques, Kevin Li Zhou, Shirley Kalogeropoulos, Kelly Schumacher, John C. Amedio, Jonathan E. Scherer, Steven R. Witowski, Richard Lombardy, Karsten Koppetsch
Publikováno v:
Organic Process Research & Development; May2009, Vol. 13 Issue 3, p535-542, 8p
Autor:
Steven R. Witowski, Robert T. Kennedy
Publikováno v:
Scopus-Elsevier
ResearcherID
ResearcherID
The chromatographic performance of capillaries with 20 and 50 μm inner diameter (i.d.) packed with 4.5 and 3.0 μm nonporous particles was evaluated under conditions of pressure- and electroosmotically-driven flow for unretained analytes with the go
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http://www.scopus.com/inward/record.url?eid=2-s2.0-0000148206&partnerID=MN8TOARS