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pro vyhledávání: '"Steven R. Pollock"'
Publikováno v:
Pharmaceutical Research. :162-167
The pharmacokinetics of adinazolam and N-desmethyladinazolam (NDMAD) were studied in 14 healthy male volunteers who received 15 mg adinazolam mesylate orally as a solution and 5 mg adinazolam mesylate intravenously in a crossover design. Two weeks pr
Publikováno v:
Clinical Pharmacology and Therapeutics. 48:652-664
The tolerance, pharmacokinetics, and pharmacodynamics of adinazolam and N-desmethyladinazolam (NDMAD) were assessed after single oral doses of 10, 30, and 50 mg adinazolam mesylate, NDMAD mesylate, and placebo. Within doses, six healthy male voluntee
Autor:
Steven R. Pollock, Lawrence S. Olanoff
Publikováno v:
Journal of Controlled Release. 11:331-341
Clinical pharmacology evaluation plays a unique and vital role in the design of novel drug delivery systems. The purpose of this review is to describe how clinical pharmacology principles and methodologies can be applied to the study and development
Autor:
Steven R. Pollock, Dennis J. Stalker
Publikováno v:
Pharmaceutical Research. :605-607
The buccal absorption of flurbiprofen was evaluated in nine normal volunteers. Twenty milliliters of 2.5 mg/ml flurbiprofen solution (pH 8.03) was administered as a 1-min mouthwash or a 5-min mouthwash or swallowed. Serum was harvested from blood sam