Zobrazeno 1 - 10
of 18
pro vyhledávání: '"Steven R. Bentley"'
Autor:
Marta F. Nabais, Simon M. Laws, Tian Lin, Costanza L. Vallerga, Nicola J. Armstrong, Ian P. Blair, John B. Kwok, Karen A. Mather, George D. Mellick, Perminder S. Sachdev, Leanne Wallace, Anjali K. Henders, Ramona A. J. Zwamborn, Paul J. Hop, Katie Lunnon, Ehsan Pishva, Janou A. Y. Roubroeks, Hilkka Soininen, Magda Tsolaki, Patrizia Mecocci, Simon Lovestone, Iwona Kłoszewska, Bruno Vellas, the Australian Imaging Biomarkers and Lifestyle study, the Alzheimer’s Disease Neuroimaging Initiative, Sarah Furlong, Fleur C. Garton, Robert D. Henderson, Susan Mathers, Pamela A. McCombe, Merrilee Needham, Shyuan T. Ngo, Garth Nicholson, Roger Pamphlett, Dominic B. Rowe, Frederik J. Steyn, Kelly L. Williams, Tim J. Anderson, Steven R. Bentley, John Dalrymple-Alford, Javed Fowder, Jacob Gratten, Glenda Halliday, Ian B. Hickie, Martin Kennedy, Simon J. G. Lewis, Grant W. Montgomery, John Pearson, Toni L. Pitcher, Peter Silburn, Futao Zhang, Peter M. Visscher, Jian Yang, Anna J. Stevenson, Robert F. Hillary, Riccardo E. Marioni, Sarah E. Harris, Ian J. Deary, Ashley R. Jones, Aleksey Shatunov, Alfredo Iacoangeli, Wouter van Rheenen, Leonard H. van den Berg, Pamela J. Shaw, Cristopher E. Shaw, Karen E. Morrison, Ammar Al-Chalabi, Jan H. Veldink, Eilis Hannon, Jonathan Mill, Naomi R. Wray, Allan F. McRae
Publikováno v:
Genome Biology, Vol 22, Iss 1, Pp 1-30 (2021)
Abstract Background People with neurodegenerative disorders show diverse clinical syndromes, genetic heterogeneity, and distinct brain pathological changes, but studies report overlap between these features. DNA methylation (DNAm) provides a way to e
Externí odkaz:
https://doaj.org/article/201eefeb04d04cf0871060b72f55eedd
Autor:
Costanza L. Vallerga, Futao Zhang, Javed Fowdar, Allan F. McRae, Ting Qi, Marta F. Nabais, Qian Zhang, Irfahan Kassam, Anjali K. Henders, Leanne Wallace, Grant Montgomery, Yu-Hsuan Chuang, Steve Horvath, Beate Ritz, Glenda Halliday, Ian Hickie, John B. Kwok, John Pearson, Toni Pitcher, Martin Kennedy, Steven R. Bentley, Peter A. Silburn, Jian Yang, Naomi R. Wray, Simon J. G. Lewis, Tim Anderson, John Dalrymple-Alford, George D. Mellick, Peter M. Visscher, Jacob Gratten
Publikováno v:
Nature Communications, Vol 11, Iss 1, Pp 1-10 (2020)
Parkinson’s disease (PD) is a common neurodegenerative disorder with a complex etiology involving genetics and the environment. Here, Vallerga et al. identify two CpG probes associated with PD in a blood cell type-corrected epigenome-wide meta-anal
Externí odkaz:
https://doaj.org/article/8ab912eda75443699d2e15309d47801d
Autor:
Steven R. Bentley, Suliman Khan, Marco Öchsner, Susitha Premarathne, Zain Aslam, Javed Y. Fowdar, Jamila Iqbal, Muhammad Naeem, Christopher A. Love, Stephen A. Wood, George D. Mellick, Alex M. Sykes
Publikováno v:
Frontiers in Neurology, Vol 11 (2020)
The study of consanguineous families has provided novel insights into genetic causes of monogenic parkinsonism. Here, we present a family from the rural Khyber Pakhtunkhwa province, Pakistan, where three siblings were diagnosed with early-onset parki
Externí odkaz:
https://doaj.org/article/5a51418bc4344b788a604a11a65095cc
Autor:
Anjali K. Henders, Marta F. Nabais, Steven R. Bentley, Ting Qi, John C. Dalrymple-Alford, Jacob Gratten, Glenda M. Halliday, Qian Zhang, Leanne Wallace, Allan F. McRae, Costanza L. Vallerga, Peter A. Silburn, Yu-Hsuan Chuang, Steve Horvath, Tim J. Anderson, Futao Zhang, Jian Yang, Grant W. Montgomery, George D. Mellick, Beate Ritz, Naomi R. Wray, John F. Pearson, Irfahan Kassam, Martin A. Kennedy, John B.J. Kwok, Simon J.G. Lewis, Javed Fowdar, Peter M. Visscher, Ian B. Hickie, Toni L. Pitcher
Publikováno v:
Nature Communications, Vol 11, Iss 1, Pp 1-10 (2020)
Nature Communications
Nature Communications
An improved understanding of etiological mechanisms in Parkinson’s disease (PD) is urgently needed because the number of affected individuals is projected to increase rapidly as populations age. We present results from a blood-based methylome-wide
Autor:
Simon J.G. Lewis, Jan H. Veldink, Iwona Kłoszewska, Jonathan Mill, Nicola J. Armstrong, Eilis Hannon, Allan F. McRae, Simon M. Laws, Pamela J. Shaw, Katie Lunnon, Pamela A. McCombe, Ammar Al-Chalabi, Anjali K. Henders, Marta F. Nabais, Alfredo Iacoangeli, Glenda M. Halliday, Susan Mathers, John B.J. Kwok, Ashley R. Jones, Anna J. Stevenson, Ian B. Hickie, Tian Lin, Cristopher E. Shaw, Ian P. Blair, Hilkka Soininen, Wouter van Rheenen, Karen E. Morrison, Jacob Gratten, Toni L. Pitcher, Ian J. Deary, Janou A. Y. Roubroeks, Shyuan T. Ngo, Tim J. Anderson, Sarah Furlong, Merrilee Needham, Peter M. Visscher, Peter A. Silburn, Ramona A. J. Zwamborn, Karen A. Mather, Patrizia Mecocci, Naomi R. Wray, Roger Pamphlett, Paul J. Hop, Garth A. Nicholson, John F. Pearson, Jian Yang, Simon Lovestone, Kelly L. Williams, Costanza L. Vallerga, Magda Tsolaki, Ehsan Pishva, Robert D. Henderson, Futao Zhang, Grant W. Montgomery, Bruno Vellas, Robert F. Hillary, Steven R. Bentley, John C. Dalrymple-Alford, Frederik J. Steyn, Riccardo E. Marioni, Dominic B. Rowe, Leanne Wallace, Leonard H. van den Berg, Aleksey Shatunov, Sarah E. Harris, Perminder S. Sachdev, Fleur C. Garton, George D. Mellick, Javed Fowder, Martin A. Kennedy
Publikováno v:
Nabais, M F, Laws, S M, Lin, T, Vallerga, C L, Armstrong, N J, Blair, I P, Kwok, J B, Mather, K A, Mellick, G D, Sachdev, P S, Wallace, L, Henders, A K, Zwamborn, R A J, Hop, P J, Lunnon, K, Pishva, E, Roubroeks, J A Y, Soininen, H, Tsolaki, M, Mecocci, P, Lovestone, S, Kłoszewska, I, Vellas, B, Furlong, S, Garton, F C, Henderson, R D, Mathers, S, Mccombe, P A, Needham, M, Ngo, S T, Nicholson, G, Pamphlett, R, Rowe, D B, Steyn, F J, Williams, K L, Anderson, T J, Bentley, S R, Dalrymple-alford, J, Fowder, J, Gratten, J, Halliday, G, Hickie, I B, Kennedy, M, Lewis, S J G, Montgomery, G W, Pearson, J, Pitcher, T L, Silburn, P, Zhang, F, Visscher, P M, Yang, J, Stevenson, A J, Hillary, R F, Marioni, R E, Harris, S E, Deary, I J, Jones, A R, Shatunov, A, Iacoangeli, A, Van Rheenen, W, Van Den Berg, L H, Shaw, P J, Shaw, C E, Morrison, K E, Al-chalabi, A, Veldink, J H, Hannon, E, Mill, J, Wray, N R & Mcrae, A F 2021, ' Meta-analysis of genome-wide DNA methylation identifies shared associations across neurodegenerative disorders ', Genome Biology, vol. 22, no. 1 . https://doi.org/10.1186/s13059-021-02275-5
Genome Biology, Vol 22, Iss 1, Pp 1-30 (2021)
Genome Biology
Genome Biology, 22(1):90. BioMed Central Ltd.
Australian Imaging Biomarkers and Lifestyle study & Alzheimer’s Disease Neuroimaging Initiative 2021, ' Meta-analysis of genome-wide DNA methylation identifies shared associations across neurodegenerative disorders ', Genome Biology, vol. 22, 90 . https://doi.org/10.1186/s13059-021-02275-5
Genome Biology, Vol 22, Iss 1, Pp 1-30 (2021)
Genome Biology
Genome Biology, 22(1):90. BioMed Central Ltd.
Australian Imaging Biomarkers and Lifestyle study & Alzheimer’s Disease Neuroimaging Initiative 2021, ' Meta-analysis of genome-wide DNA methylation identifies shared associations across neurodegenerative disorders ', Genome Biology, vol. 22, 90 . https://doi.org/10.1186/s13059-021-02275-5
Background People with neurodegenerative disorders show diverse clinical syndromes, genetic heterogeneity, and distinct brain pathological changes, but studies report overlap between these features. DNA methylation (DNAm) provides a way to explore th
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::222e9540511330ced2d46144bc1f420e
https://zenodo.org/record/4643029
https://zenodo.org/record/4643029
Autor:
Holly E. Sherman, Stephen A. Wood, Alex M. Sykes, Peter A. Silburn, Steven R. Bentley, Ilaria Guella, Hannah M. Neuendorf, Javed Fowdar, Matthew J. Farrer, George D. Mellick
Publikováno v:
Genes, Vol 12, Iss 430, p 430 (2021)
Genes
Volume 12
Issue 3
Genes
Volume 12
Issue 3
Parkinson’s disease (PD) is typically sporadic
however, multi-incident families provide a powerful platform to discover novel genetic forms of disease. Their identification supports deciphering molecular processes leading to disease and may in
however, multi-incident families provide a powerful platform to discover novel genetic forms of disease. Their identification supports deciphering molecular processes leading to disease and may in
Publikováno v:
Microbiology Resource Announcements
Halomonas sp. strain KAO is an aerobic, Mn(II)-oxidizing, halophilic bacterium. The draft genome of the isolate contains 47 contigs encompassing 3.7 Mb and a G+C content of 64.22%. This sequence will provide essential information for future studies o
Autor:
Melissa A. Hill, Steven R. Bentley, Tara L. Walker, George D. Mellick, Stephen A. Wood, Alex M. Sykes
Publikováno v:
PloS one. 17(7)
The genetic study of multi-incident families is a powerful tool to investigate genetic contributions to the development of Parkinson’s disease. In this study, we identified the rare PTPRA p.R223W variant as one of three putative genetic factors pot
Publikováno v:
Microbiology Resource Announcements. 9
Halomonas sp. strain ML-15 is an aerobic, haloalkaliphilic bacterium capable of degrading polycyclic aromatic hydrocarbons (PAHs). The draft genome sequence of the isolate contains 19 contigs encompassing 4.8 Mb and a G+C content of 65.38%. This sequ
Publikováno v:
J Spinal Cord Med
Context/objective: To identify themes of interest for the production of educational resources for people with spinal cord injury (SCI). Design: A mixed-method study. Setting: Outpatient SCI community in Australia. Participants: Individuals with a SCI
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::33362f491d5f9cab7e653ac99940879b
https://europepmc.org/articles/PMC9135423/
https://europepmc.org/articles/PMC9135423/