Zobrazeno 1 - 10
of 239
pro vyhledávání: '"Steven R Kleeberger"'
Autor:
Alison K Bauer, Hye-Youn Cho, Laura Miller-Degraff, Christopher Walker, Katherine Helms, Jennifer Fostel, Masayuki Yamamoto, Steven R Kleeberger
Publikováno v:
PLoS ONE, Vol 6, Iss 10, p e26590 (2011)
Nrf2 is a key transcription factor that regulates cellular redox and defense responses. However, permanent Nrf2 activation in human lung carcinomas promotes pulmonary malignancy and chemoresistance. We tested the hypothesis that Nrf2 has cell surviva
Externí odkaz:
https://doaj.org/article/2cebfbd6492f46e6803867495c6c1bee
Autor:
Xuting Wang, Brian N Chorley, Gary S Pittman, Steven R Kleeberger, John Brothers, Gang Liu, Avrum Spira, Douglas A Bell
Publikováno v:
PLoS ONE, Vol 5, Iss 8, p e11934 (2010)
Prior microarray studies of smokers at high risk for lung cancer have demonstrated that heterogeneity in bronchial airway epithelial cell gene expression response to smoking can serve as an early diagnostic biomarker for lung cancer. As a first step
Externí odkaz:
https://doaj.org/article/920782602b294c528d9f271cb06baab0
Autor:
Hye-Youn Cho, Xuting Wang, Michelle R. Campbell, Vijayalakshmi Panduri, Silvina Coviello, Mauricio T. Caballero, Brian D. Bennett, Steven R. Kleeberger, Fernando P. Polack, Gaston Ofman, Douglas A. Bell
Publikováno v:
Scientific Reports, Vol 13, Iss 1, Pp 1-21 (2023)
Abstract Bronchopulmonary dysplasia (BPD) is a prevalent chronic lung disease of prematurity with limited treatment options. To uncover biomarkers of BPD risk, this study investigated epigenetic and transcriptomic signatures of prematurity at birth a
Externí odkaz:
https://doaj.org/article/8cb45c3ead1241fc8305deb96342b095
Autor:
William D. Figg, Alex Sparreboom, Christopher Cabell, Douglas R. Rosing, Douglas K. Price, Susan E. Bates, Steven R. Kleeberger, David Liewehr, David Venzon, Seth M. Steinberg, Laura Miller-DeGraff, James A. Clark, Ryan Franke, Sukyung Woo, Xiaohong Chen, Reuben Howden, Richard L. Piekarz, Erin R. Gardner, Tristan M. Sissung
Supplementary Results.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::374d0e8e17ab87845ca4fa5bface3087
https://doi.org/10.1158/1078-0432.22441443
https://doi.org/10.1158/1078-0432.22441443
Autor:
William D. Figg, Alex Sparreboom, Christopher Cabell, Douglas R. Rosing, Douglas K. Price, Susan E. Bates, Steven R. Kleeberger, David Liewehr, David Venzon, Seth M. Steinberg, Laura Miller-DeGraff, James A. Clark, Ryan Franke, Sukyung Woo, Xiaohong Chen, Reuben Howden, Richard L. Piekarz, Erin R. Gardner, Tristan M. Sissung
Supplementary Methods.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1a0baf4c3da463868c4c2a78d4c3771f
https://doi.org/10.1158/1078-0432.22441446
https://doi.org/10.1158/1078-0432.22441446
Autor:
William D. Figg, Alex Sparreboom, Christopher Cabell, Douglas R. Rosing, Douglas K. Price, Susan E. Bates, Steven R. Kleeberger, David Liewehr, David Venzon, Seth M. Steinberg, Laura Miller-DeGraff, James A. Clark, Ryan Franke, Sukyung Woo, Xiaohong Chen, Reuben Howden, Richard L. Piekarz, Erin R. Gardner, Tristan M. Sissung
Supplementary Figure S1.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::320cdf8074116467faacb5a7d3506906
https://doi.org/10.1158/1078-0432.22441449
https://doi.org/10.1158/1078-0432.22441449
Autor:
Steven R. Kleeberger, Robert Langenbach, Soojung Park, Laura Miller, Hye-Youn Cho, Huei-Chen Lee
Publikováno v:
Toxicol Pathol
Mucin-5AC (MUC5AC) is a major secreted mucin in pathogenic airways. To determine its role in mucus-related airway disorders, Muc5ac-deficient ( Muc5ac−/−) and wild-type ( Muc5ac+/+) mice were compared in bleomycin-induced pulmonary fibrosis, resp
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f29520af5eb7d6bf023f865f077c0a8a
https://doi.org/10.1177/01926233211004433
https://doi.org/10.1177/01926233211004433
Autor:
Steven R. Kleeberger, Ryan J. Snyder
Publikováno v:
Comprehensive Physiology
The mitochondrial genome is a small, circular, and highly conserved piece of DNA which encodes only 13 protein subunits yet is vital for electron transport in the mitochondrion and, therefore, vital for the existence of multicellular life on Earth. D
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::22e04f0fb0464876ee8f4cfdac838e76
https://doi.org/10.1002/cphy.c200010
https://doi.org/10.1002/cphy.c200010
Autor:
Hye‐Youn Cho, Xuting Wang, Michelle R. Campbell, Vijayalakshmi Panduri, Silvina Coviello, Mauricio T. Caballero, Deepa Sambandan, Steven R. Kleeberger, Fernando P. Polack, Gaston Ofman, Douglas A. Bell
Publikováno v:
The FASEB Journal. 36
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::2c7e9b4e815bed8158b834147f0b0a81
https://doi.org/10.1096/fasebj.2022.36.s1.r2648
https://doi.org/10.1096/fasebj.2022.36.s1.r2648
Autor:
Heather L. Vellers, Hye-Youn Cho, Wesley Gladwell, Kevin Gerrish, Janine H. Santos, Gaston Ofman, Laura Miller-DeGraff, T. Beth Mahler, Steven R. Kleeberger
Publikováno v:
Antioxidants; Volume 11; Issue 4; Pages: 760
Approximately 1 in 10 newborns are born preterm and require supplemental oxygen (O2) in an extrauterine environment following birth. Supplemental O2 can induce oxidative stress that can impair mitochondrial function, resulting in lung injury and incr
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::13b719a1950215e2a136d59230452e2c
https://pubmed.ncbi.nlm.nih.gov/35453445
https://pubmed.ncbi.nlm.nih.gov/35453445