Zobrazeno 1 - 2
of 2
pro vyhledávání: '"Steven Philip Keeling"'
Autor:
Steven Philip Keeling, Nigel J. Parr, Simon Teanby Hodgson, Ashley Paul Hancock, Duncan S. Holmes, Panayiotis A. Procopiou, James E. Rowedder, Brian Edgar Looker, Robert J. Slack, Paul Martin Gore, Rachael A. Ancliff
Publikováno v:
Bioorganic & Medicinal Chemistry Letters. 26:5855-5859
A novel series of potent quinoline-based human H1 and H3 bivalent histamine receptor antagonists, suitable for intranasal administration for the potential treatment of allergic rhinitis associated nasal congestion, were identified. Compound 18b had s
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::d45d14b9a3273b85467445965e61386d
https://doi.org/10.1016/j.bmcl.2016.11.022
https://doi.org/10.1016/j.bmcl.2016.11.022
Autor:
Simon J. F. Macdonald, Philip Alan Skone, Ian B. Campbell, Diane M. Coe, Tony W. J. Cooper, Gordon A. Weingarten, Peter W. Sutton, Deborah Needham, George Hardy, Tracy Jane Shipley, Haydn Terence Jones, Torquil I. Jack, Steven Philip Keeling
Publikováno v:
Tetrahedron Letters. 49:5101-5104
The efficient synthesis of an α-trifluoromethyl-α-tosyloxymethyl epoxide is reported. This highly versatile building block may be reacted sequentially with two different nucleophiles to furnish α-trifluoromethyl tertiary alcohols. Furthermore, the
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::39e5ddf37cef54e5d27b966049701f90
https://doi.org/10.1016/j.tetlet.2008.06.011
https://doi.org/10.1016/j.tetlet.2008.06.011