Zobrazeno 1 - 10
of 13
pro vyhledávání: '"Steven P. Mah"'
Autor:
Steven P. Mah, David Lo, David J. Brayden, Daragh Byrne, Daniel J. O'mahony, Brian S. Hilbush, Lisa Higgins
Publikováno v:
Advanced Drug Delivery Reviews. 54:1213-1223
Drug delivery technologies are commonly directed towards formulations to control the delivery of therapeutic compounds. However, many processes in the human body have evolved to regulate the transport of various molecules, cells, or particles across
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e2548b279ee0dac9c88f58ec29bd6b45
https://doi.org/10.1016/s0169-409x(02)00091-1
https://doi.org/10.1016/s0169-409x(02)00091-1
Publikováno v:
Developmental Biology. 223:38-53
During nephrogenesis, dynamic changes in the expression of cell adhesion molecules are evident as epithelial structures differentiate from the induced mesenchyme. The cadherins are thought to play an important role in the metanephric mesenchyme, when
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::494f5d56772e6376f89681ae300d1ef9
https://doi.org/10.1006/dbio.2000.9738
https://doi.org/10.1006/dbio.2000.9738
Autor:
Steven P. Maher, Amélie Vantaux, Victor Chaumeau, Adeline C. Y. Chua, Caitlin A. Cooper, Chiara Andolina, Julie Péneau, Mélanie Rouillier, Zaira Rizopoulos, Sivchheng Phal, Eakpor Piv, Chantrea Vong, Sreyvouch Phen, Chansophea Chhin, Baura Tat, Sivkeng Ouk, Bros Doeurk, Saorin Kim, Sangrawee Suriyakan, Praphan Kittiphanakun, Nana Akua Awuku, Amy J. Conway, Rays H. Y. Jiang, Bruce Russell, Pablo Bifani, Brice Campo, François Nosten, Benoît Witkowski, Dennis E. Kyle
Publikováno v:
Scientific Reports, Vol 11, Iss 1, Pp 1-18 (2021)
Abstract Improved control of Plasmodium vivax malaria can be achieved with the discovery of new antimalarials with radical cure efficacy, including prevention of relapse caused by hypnozoites residing in the liver of patients. We screened several com
Externí odkaz:
https://doaj.org/article/82bd81cce09f483dac02985c053a9b50
Autor:
Amélie Vantaux, Julie Péneau, Caitlin A. Cooper, Dennis E. Kyle, Benoit Witkowski, Steven P. Maher
Publikováno v:
Frontiers in Microbiology, Vol 13 (2022)
Plasmodium vivax, one species of parasite causing human malaria, forms a dormant liver stage, termed the hypnozoite, which activate weeks, months or years after the primary infection, causing relapse episodes. Relapses significantly contribute to the
Externí odkaz:
https://doaj.org/article/b308d2614d024f41b268c7ed1f62fb52
Autor:
Anthony A. Ruberto, Steven P. Maher, Amélie Vantaux, Chester J. Joyner, Caitlin Bourke, Balu Balan, Aaron Jex, Ivo Mueller, Benoit Witkowski, Dennis E. Kyle
Publikováno v:
Frontiers in Cellular and Infection Microbiology, Vol 12 (2022)
The resilience of Plasmodium vivax, the most widely-distributed malaria-causing parasite in humans, is attributed to its ability to produce dormant liver forms known as hypnozoites, which can activate weeks, months, or even years after an initial mos
Externí odkaz:
https://doaj.org/article/d4574b7d96d4492ebe513519b0913d9a
Autor:
Carson Bowers, Lisa Hancox, Kristen Peissig, Justine C. Shiau, Amélie Vantaux, Benoit Witkowski, Sivchheng Phal, Steven P. Maher, John T. Harty, Dennis E. Kyle, Samarchith P. Kurup
Publikováno v:
Pathogens, Vol 11, Iss 12, p 1487 (2022)
Malaria is a deadly disease caused by the parasite, Plasmodium, and impacts the lives of millions of people around the world. Following inoculation into mammalian hosts by infected mosquitoes, the sporozoite stage of Plasmodium undergoes obligate dev
Externí odkaz:
https://doaj.org/article/7681f67d916f4392a1baa9aed41e8e95
Autor:
Larry T. Patterson, Gregory R. Dressler, Chris Kintner, Eun Ah Cho, William T. Brookhiser, Steven P. Mah
Publikováno v:
Development (Cambridge, England). 125(5)
The cadherin gene family encodes calcium-dependent adhesion molecules that promote homophilic interactions among cells. During embryogenesis, differential expression of cadherins can drive morphogenesis by stimulating cell aggregation, defining bound
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::79863f1b53db14abd52e0f09427714db
https://pubmed.ncbi.nlm.nih.gov/9449663
https://pubmed.ncbi.nlm.nih.gov/9449663
Autor:
Kayla Sylvester, Steven P. Maher, Dora Posfai, Michael K. Tran, McKenna C. Crawford, Amélie Vantaux, Benoît Witkowski, Dennis E. Kyle, Emily R. Derbyshire
Publikováno v:
Frontiers in Cellular and Infection Microbiology, Vol 11 (2021)
Plasmodium is a genus of apicomplexan parasites which replicate in the liver before causing malaria. Plasmodium vivax can also persist in the liver as dormant hypnozoites and cause clinical relapse upon activation, but the molecular mechanisms leadin
Externí odkaz:
https://doaj.org/article/eb61cd7ba2e44e8685764525ca944d4d
Autor:
Steven P. Mah, Li-tao Zhong, Robert H. Edwards, Theodore A. Sarafian, Dale E. Bredesen, Andrew Charles, Darci J. Kane
Publikováno v:
Proceedings of the National Academy of Sciences of the United States of America. 90(10)
The protooncogene bcl-2, which has been implicated in B-cell lymphoma development, inhibits apoptosis due to growth factor withdrawal in some, but not all, hematopoietic cells. Recently we found that bcl-2 also inhibits apoptosis in PC12 pheochromocy
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6360a1679b68cb07013ed3622cc6c919
https://pubmed.ncbi.nlm.nih.gov/8506295
https://pubmed.ncbi.nlm.nih.gov/8506295
Autor:
Adeline C. Y. Chua, Jessica Jie Ying Ong, Benoit Malleret, Rossarin Suwanarusk, Varakorn Kosaisavee, Anne-Marie Zeeman, Caitlin A. Cooper, Kevin S. W. Tan, Rou Zhang, Bee Huat Tan, Siti Nurdiana Abas, Andy Yip, Anne Elliot, Chester J. Joyner, Jee Sun Cho, Kate Breyer, Szczepan Baran, Amber Lange, Steven P. Maher, François Nosten, Christophe Bodenreider, Bryan K. S. Yeung, Dominique Mazier, Mary R. Galinski, Nathalie Dereuddre-Bosquet, Roger Le Grand, Clemens H. M. Kocken, Laurent Rénia, Dennis E. Kyle, Thierry T. Diagana, Georges Snounou, Bruce Russell, Pablo Bifani
Publikováno v:
Nature Communications, Vol 10, Iss 1, Pp 1-13 (2019)
Present understanding of Plasmodium vivax biology is hampered by its inability to grow in vitro. Here, the authors developed an in vitro culture of its simian counterpart, P. cynomolgi, which shares morphological and phenotypic similarities with P. v
Externí odkaz:
https://doaj.org/article/68f08622b7b941e08fb8d5ecab44264a