Zobrazeno 1 - 10
of 50
pro vyhledávání: '"Steven P Maher"'
Autor:
Anthony A Ruberto, Caitlin Bourke, Amélie Vantaux, Steven P Maher, Aaron Jex, Benoit Witkowski, Georges Snounou, Ivo Mueller
Publikováno v:
PLoS Neglected Tropical Diseases, Vol 16, Iss 8, p e0010633 (2022)
BackgroundPlasmodium vivax sporozoites reside in the salivary glands of a mosquito before infecting a human host and causing malaria. Previous transcriptome-wide studies in populations of these parasite forms were limited in their ability to elucidat
Externí odkaz:
https://doaj.org/article/e86c83b8dd0d45d781a5cf73f6cb53a2
Publikováno v:
PLoS ONE, Vol 5, Iss 10, p e13282 (2010)
A majority of the Plasmodium falciparum genome codes for genes with unknown functions, which presents a major challenge to understanding the parasite's biology. Large-scale functional analysis of the parasite genome is essential to pave the way for n
Externí odkaz:
https://doaj.org/article/80c66d42375644a4bc620ea4a0d8d082
Autor:
Joseph M Gonzales, Jigar J Patel, Napawan Ponmee, Lei Jiang, Asako Tan, Steven P Maher, Stefan Wuchty, Pradipsinh K Rathod, Michael T Ferdig
Publikováno v:
PLoS Biology, Vol 6, Iss 9, p e238 (2008)
The determinants of transcriptional regulation in malaria parasites remain elusive. The presence of a well-characterized gene expression cascade shared by different Plasmodium falciparum strains could imply that transcriptional regulation and its nat
Externí odkaz:
https://doaj.org/article/3d2ec73fda614dc993d71311943872b6
Autor:
Carson Bowers, Lisa Hancox, Kristen Peissig, Justine C. Shiau, Amélie Vantaux, Benoit Witkowski, Sivchheng Phal, Steven P. Maher, John T. Harty, Dennis E. Kyle, Samarchith P. Kurup
Publikováno v:
Pathogens, Vol 11, Iss 12, p 1487 (2022)
Malaria is a deadly disease caused by the parasite, Plasmodium, and impacts the lives of millions of people around the world. Following inoculation into mammalian hosts by infected mosquitoes, the sporozoite stage of Plasmodium undergoes obligate dev
Externí odkaz:
https://doaj.org/article/7681f67d916f4392a1baa9aed41e8e95
Autor:
Alona Botnar, Grant Lawrence, Steven P. Maher, Amélie Vantaux, Benoît Witkowski, Justine C. Shiau, Emilio F. Merino, David De Vore, Christian Yang, Cameron Murray, Maria B. Cassera, James W. Leahy, Dennis E. Kyle
Publikováno v:
International Journal for Parasitology. 52:733-744
Malaria is a major global health problem which predominantly afflicts developing countries. Although many antimalarial therapies are currently available, the protozoan parasite causing this disease, Plasmodium spp., continues to evade eradication eff
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e189c9d5cd5dcf417e915e7f746d84e1
https://doi.org/10.1016/j.ijpara.2022.03.003
https://doi.org/10.1016/j.ijpara.2022.03.003
Autor:
Yuxiang Dong, Yogesh Sonawane, Steven P. Maher, Anne-Marie Zeeman, Victor Chaumeau, Amélie Vantaux, Caitlin A. Cooper, Francis C. K. Chiu, Eileen Ryan, Jenna McLaren, Gong Chen, Sergio Wittlin, Benoît Witkowski, François Nosten, Kamaraj Sriraghavan, Dennis E. Kyle, Clemens H. M. Kocken, Susan A. Charman, Jonathan L. Vennerstrom
Publikováno v:
ACS Omega. 7:12401-12411
The catechol derivative RC-12 (WR 27653) (
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e050e54dd84232f0b99386c14fc1b10a
https://doi.org/10.1021/acsomega.2c01099
https://doi.org/10.1021/acsomega.2c01099
Autor:
Carson, Bowers, Lisa, Hancox, Kristen, Peissig, Justine C, Shiau, Amélie, Vantaux, Benoit, Witkowski, Sivchheng, Phal, Steven P, Maher, John T, Harty, Dennis E, Kyle, Samarchith P, Kurup
Publikováno v:
Pathogens (Basel, Switzerland). 11(12)
Malaria is a deadly disease caused by the parasite
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::e49dd97c56d6d70ca03bc3ce26e59e30
https://pubmed.ncbi.nlm.nih.gov/36558821
https://pubmed.ncbi.nlm.nih.gov/36558821
Autor:
Amélie Vantaux, Julie Péneau, Caitlin A. Cooper, Dennis E. Kyle, Benoit Witkowski, Steven P. Maher
Publikováno v:
Frontiers in Microbiology. 13
Plasmodium vivax, one species of parasite causing human malaria, forms a dormant liver stage, termed the hypnozoite, which activate weeks, months or years after the primary infection, causing relapse episodes. Relapses significantly contribute to the
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f154b47dcef7f015646c5c7ccc786077
Autor:
Anthony A. Ruberto, Steven P. Maher, Amélie Vantaux, Chester J. Joyner, Caitlin Bourke, Balu Balan, Aaron Jex, Ivo Mueller, Benoit Witkowski, Dennis E. Kyle
Publikováno v:
Frontiers in Cellular and Infection Microbiology. 12
The resilience of Plasmodium vivax, the most widely-distributed malaria-causing parasite in humans, is attributed to its ability to produce dormant liver forms known as hypnozoites, which can activate weeks, months, or even years after an initial mos
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::4354db626bd9ab715fb25880d6bd1174
https://doi.org/10.3389/fcimb.2022.986314
https://doi.org/10.3389/fcimb.2022.986314
Autor:
Raahil S. Patel, Brice Campo, Jetsumon Sattabongkot, Steven P. Maher, Chris Palmiotti, Chiara Andolina, Rays H. Y. Jiang, Alison Roth, Phillip Cualing, Dennis E. Kyle, Jessica Turgeon, Robert Carter, John H. Adams, Swamy R. Adapa, Wajeeh M. Saadi, Virginia Van Grod, François Nosten, Amy J. Conway, Myles E. Johnson, Samantha J. Barnes, Naresh Singh, H-C Steve Sun, Victor Chaumeau, James C. Hsiao
Publikováno v:
Lab on a Chip. 20:1124-1139
Advanced cell culture methods for modeling organ-level structure have been demonstrated to replicate in vivo conditions more accurately than traditional in vitro cell culture. Given that the liver is particularly important to human health, several ad
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0b5926a5d714e8c45a09f91b21b579d0
https://doi.org/10.1039/c9lc00921c
https://doi.org/10.1039/c9lc00921c