Zobrazeno 1 - 3
of 3
pro vyhledávání: '"Steven P Keeling"'
Autor:
Christopher R. Wellaway, Ian R. Baldwin, Paul Bamborough, Daniel Barker, Michelle A. Bartholomew, Chun-wa Chung, Birgit Dümpelfeld, John P. Evans, Neal J. Fazakerley, Paul Homes, Steven P. Keeling, Xiao Q. Lewell, Finlay W. McNab, Joanne Morley, Deborah Needham, Margarete Neu, Antoon J. M. van Oosterhout, Anshu Pal, Friedrich B. M. Reinhard, Francesco Rianjongdee, Craig M. Robertson, Paul Rowland, Rishi R. Shah, Emma B. Sherriff, Lisa A. Sloan, Simon Teague, Daniel A. Thomas, Natalie Wellaway, Justyna Wojno-Picon, James M. Woolven, Diane M. Coe
Publikováno v:
Journal of Medicinal Chemistry. 65:633-664
The Janus family of tyrosine kinases (JAK1, JAK2, JAK3, and TYK2) play an essential role in the receptor signaling of cytokines that have been implicated in the pathogenesis of severe asthma, and there is emerging interest in the development of small
Autor:
Panayiotis A, Procopiou, Rachael A, Ancliff, Paul M, Gore, Ashley P, Hancock, Simon T, Hodgson, Duncan S, Holmes, Steven P, Keeling, Brian E, Looker, Nigel A, Parr, James E, Rowedder, Robert J, Slack
Publikováno v:
Bioorganicmedicinal chemistry letters. 26(24)
A novel series of potent quinoline-based human H
Autor:
Paul S. Jones, Steven P Keeling, Stephen Swanson, David Cedric Humber, Paul F Martin, Peter C. Cherry, David M. Andrews, Caroline D Shaw
Publikováno v:
European journal of medicinal chemistry. 34(7-8)
Analogues of 4-Guanidino-Neu5Ac2en (Zanamivir) have been prepared containing carbamate substituents at the 7-hydroxy position. (4S,5R,6R)-5-Acetylamino-6-{1R-[(6-aminohexyl)carbamoyloxy]-2R,3-dihydroxypropyl}-4-guanidino-5,6-dihydro-4H-pyran-2carboxy