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Autor:
David Howland, Angela Chen, Liliana B. Menalled, Dani Brunner, Steven Oakeshott, Washington Arias, Carol Murphy, Dansha He, Andrew M. Farrar, William Alosio, Sylvie Ramboz, Neil E. Paterson, Larry Park
Publikováno v:
International Journal of Comparative Psychology. 27
The neurodegenerative disorder Huntington’s disease (HD) is characterized by motor dysfunction, cognitive impairment and psychiatric symptoms. The R6/2 (120 CAG repeats) mouse model of HD recapitulates many of the symptoms of the disease, including