Zobrazeno 1 - 10
of 279
pro vyhledávání: '"Steven N. Hochwald"'
Publikováno v:
Phytomedicine Plus, Vol 3, Iss 1, Pp 100396- (2023)
Introduction: Medicinal plants and their highly valuable compounds are used worldwide as therapeutic interventions for the management of complex, multifactorial physiologic imbalances, and various other health problems including cancer. However, the
Externí odkaz:
https://doaj.org/article/95be5866a5214a3e974107ff4db1039c
Autor:
Jianliang Zhang, Irwin H. Gelman, Eriko Katsuta, Yuanzi Liang, Xue Wang, Jun Li, Jun Qu, Li Yan, Kazuaki Takabe, Steven N. Hochwald
Publikováno v:
Cellular and Molecular Gastroenterology and Hepatology, Vol 8, Iss 1, Pp 37-60 (2019)
Background & Aims: Most targeted therapies against cancer are designed to block growth factor–stimulated oncogenic growth. However, response rates are low, and resistance to therapy is high. One mechanism might relate to the ability of tumor cells
Externí odkaz:
https://doaj.org/article/74e2c81b333044c0b4f350fb137465bb
Autor:
Shruti G. Dighe, Li Yan, Sarbajit Mukherjee, Cailey S. McGillicuddy, Karen L. Hulme, Steven N. Hochwald, Saikrishna Yendamuri, Andrew J. Bain, Kevin T. Robillard, Kirsten B. Moysich, Christine B. Ambrosone, Amy E. Millen, Matthew F. Buas
Publikováno v:
Cancers, Vol 13, Iss 18, p 4653 (2021)
Purpose: The incidence of esophageal adenocarcinoma (EAC) has risen substantially in recent decades, while the average 5-year survival remains only ~20%. Disease stage and treatment are the strongest prognostic factors. The role of lifestyle factors
Externí odkaz:
https://doaj.org/article/c97db61f16f14d5db4b9d298792698fb
Publikováno v:
Journal of Surgical Research. 290:2-8
Publikováno v:
Oncogene. 42:449-460
Autor:
Maria Zajac-Kaye, Patricia Steeg, Victor E. Marquez, Steven N. Hochwald, Frederic J. Kaye, Kent W. Hunter, Melinda Hollingshead, Kevin D. Brown, Lisa M. Dyer, Sherry X. Yang, Akbar Nawab, Daniel Shabashvili, Min Chen
PDF file - 235K, mRNA expression levels in normal mammary glands, mammary tumors and tumors from zebularine treated mice.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2d6dd3a0549c4872ceb4ecc0c51937f4
https://doi.org/10.1158/1535-7163.22498743
https://doi.org/10.1158/1535-7163.22498743
Autor:
Maria Zajac-Kaye, Patricia Steeg, Victor E. Marquez, Steven N. Hochwald, Frederic J. Kaye, Kent W. Hunter, Melinda Hollingshead, Kevin D. Brown, Lisa M. Dyer, Sherry X. Yang, Akbar Nawab, Daniel Shabashvili, Min Chen
PDF file - 335K, Differentially down-regulated genes (>1.5-fold differences; P < 0.05) from mammary tumors of the PyMT transgenic mice exposed to zebularine for 48 days.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6d6ec7089af8890cc4aa438aad93b67f
https://doi.org/10.1158/1535-7163.22498746
https://doi.org/10.1158/1535-7163.22498746
Autor:
Maria Zajac-Kaye, Patricia Steeg, Victor E. Marquez, Steven N. Hochwald, Frederic J. Kaye, Kent W. Hunter, Melinda Hollingshead, Kevin D. Brown, Lisa M. Dyer, Sherry X. Yang, Akbar Nawab, Daniel Shabashvili, Min Chen
Zebularine is a novel potent inhibitor of both cytidine deaminase and DNA methylation. We examined the effect of zebularine on mammary tumor growth in genetically engineered MMTV-PyMT transgenic mice that develop mammary tumors at 60 days of age with
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6ceaeb894e86e4d512274059ee6064d2
https://doi.org/10.1158/1535-7163.c.6535962
https://doi.org/10.1158/1535-7163.c.6535962
Autor:
Maria Zajac-Kaye, Patricia Steeg, Victor E. Marquez, Steven N. Hochwald, Frederic J. Kaye, Kent W. Hunter, Melinda Hollingshead, Kevin D. Brown, Lisa M. Dyer, Sherry X. Yang, Akbar Nawab, Daniel Shabashvili, Min Chen
PDF file - 262K, Differentially up-regulated genes (>1.5-fold differences; P < 0.05) from mammary tumors of the PyMT transgenic mice exposed to zebularine for 23 days.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::04ac89a8b79027ae982819d88555dfe1
https://doi.org/10.1158/1535-7163.22498755
https://doi.org/10.1158/1535-7163.22498755
Autor:
Maria Zajac-Kaye, Patricia Steeg, Victor E. Marquez, Steven N. Hochwald, Frederic J. Kaye, Kent W. Hunter, Melinda Hollingshead, Kevin D. Brown, Lisa M. Dyer, Sherry X. Yang, Akbar Nawab, Daniel Shabashvili, Min Chen
PDF file - 396K, Differentially up-regulated genes (>1.5-fold differences; P < 0.05) from mammary tumors of the PyMT transgenic mice exposed to zebularine for 48 days.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4f7ae218cdda4b07168e0e779952df60
https://doi.org/10.1158/1535-7163.22498749
https://doi.org/10.1158/1535-7163.22498749