Zobrazeno 1 - 10
of 85
pro vyhledávání: '"Steven N. Emancipator"'
Publikováno v:
Microorganisms, Vol 10, Iss 12, p 2407 (2022)
Since influenza and coronaviruses are currently deadly and emerging threats worldwide, better treatment, remediation and prevention options are needed. In that regard, a basic understanding of severe acute respiratory syndrome (SARS)-CoV-2/COVID-19 (
Externí odkaz:
https://doaj.org/article/8d432bcc801242c09d02b0f6e55f3259
Autor:
Hiroyuki Inoshita, Byung-Gyu Kim, Michifumi Yamashita, Sung Hee Choi, Yasuhiko Tomino, John J Letterio, Steven N Emancipator
Publikováno v:
PLoS ONE, Vol 8, Iss 11, p e78736 (2013)
The link between glomerular IgA nephropathy (IgAN) and T helper 2 (Th2) response has been implicated, however, the mechanisms are poorly defined because of the lack of an appropriate model. Here we report a novel murine model characterized by lineage
Externí odkaz:
https://doaj.org/article/b19a19028de74cb88825c6d6571b696a
Autor:
Rosanna Coppo, Francesco Emma, François Berthoux, Kensuke Joh, Haiyan Wang, Daniel C. Cattran, Giuseppe D'Amico, F. Paolo Schena, Franco Ferrario, Olga Vorobyeva, Shubha Bellur, Fernand Mac-Moune Lai, N Yoshikawa, Stéphan Troyanov, Alessandro Amore, Vivette D. D'Agati, Jan J. Weening, Stephen I-Hong Hsu, Charles E. Alpers, Jonathan Barratt, J. Charles Jennette, Fanny Lepeytre, Fernando C. Fervenza, John Feehally, Sandrine Florquin, Agnes B. Fogo, Tetsuya Kawamura, Bruce Mackinnon, H. Terence Cook, Hong Zhang, Zhihong Liu, Philip Kam-Tao Li, Mark Haas, Jan A. Bruijn, Colin C. Geddes, Ian Roberts, Ronald J. Hogg, Hermann-Josef Groene, Lei-Shi Li, Prue Hill, Steven N. Emancipator, Andrew M. Herzenberg, Yasuhiko Tomino, Sergio Mezzano, Stephen M. Bonsib, Bruce A. Julian, Patrick D. Walker
Publikováno v:
Kidney international, 91(1), 235-243. Nature Publishing Group
Focal segmental glomerulosclerosis (FSGS) is a common finding in IgA nephropathy (IgAN). Here we assessed FSGS lesions in the Oxford Classification patient cohort and correlated histology with clinical presentation and outcome to determine whether su
Autor:
Steven N. Emancipator, Mark E. Obrenovich, Alex Polinkovsky, Curtis J. Donskey, Renliang Zhang, Mary Ann Tima
Antibiotics excreted into the intestinal tract may disrupt the microbiota that provide colonization resistance against enteric pathogens and alter normal metabolic functions of the microbiota. Many of the bacterial metabolites produced in the intesti
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ffc670df7d5b3c3ee9e8e08dcce6cb9e
https://europepmc.org/articles/PMC5527637/
https://europepmc.org/articles/PMC5527637/
Autor:
Yoshio Ootaki, Tetsuya Horai, Alex Massiello, Michifumi Yamashita, Diyar Saeed, Chiyo Ootaki, Leonard A.R. Golding, Kiyotaka Fukamachi, Steven N. Emancipator, Hideyuki Fumoto
Publikováno v:
The Annals of Thoracic Surgery. 96:148-154
We previously reported renal arterial periarteritis after implantation of a continuous-flow left ventricular assist device in calves. The purpose of the present study was to investigate whether the same periarteritis changes occur in the intrapulmona
Autor:
Paramananda Saikia, Carrie A. Millward, Michifumi Yamashita, Hiroyuki Inoshita, Saurabh Chattopadhyay, Steven N. Emancipator, Ganes C. Sen
Publikováno v:
Journal of Innate Immunity. 5:231-241
Immunoglobulin A nephropathy (IgAN) is the most common form of glomerulonephritis throughout the world. A majority (approx. 60%) of patients with IgAN experience disease exacerbations associated with an acute respiratory or gastrointestinal illness t
Autor:
Toshinao Tsuge, Satoshi Horikoshi, Steven N. Emancipator, Yusuke Suzuki, Noriyoshi Kobayashi, Koshi Yamada, Yasuhiko Tomino, Tomomi Ikeda
Publikováno v:
Nephrology Dialysis Transplantation
Background Patients with IgA nephropathy (IgAN) have an increased amount of abnormally O-glycosylated IgA1 in circulation, in glomerular deposits and produced by tissue cells in vitro. Although increased production of Th2 cytokines by peripheral bloo
Autor:
Clifford V. Harding, Gareth Hardy, Steven N. Emancipator, Derek W. Abbott, Reginald Courtney Gray, John Kuchtey, Yi Liu
Publikováno v:
The Journal of Immunology. 184:3367-3376
CpG oligodeoxynucleotides (ODNs) signal through TLR9 to induce type I IFN (IFN-alphabeta) in dendritic cells (DCs). CpG-A ODNs are more efficacious than CpG-B ODNs for induction of IFN-alphabeta. Because IFN-alphabeta may contribute to autoimmunity,
Autor:
Steven N. Emancipator, Thomas G. Blanchard, Michifumi Yamashita, Michael E. Lamm, Nayer Bagheri, Yasuhiko Tomino, John G. Nedrud, Subba R. Chintalacharuvu
Publikováno v:
Clinical and Experimental Immunology. 153:456-462
SummaryImmunoglobulin A (IgA) glycosylation, recognized as an important pathogenic factor in IgA nephropathy (IgAN), is apparently controlled by the polarity of T helper (Th) cytokine responses. To examine the role of cytokine polarity in IgAN, inbre
Autor:
Steven N. Emancipator, Jiazhou Qiu, Janet Robinson, Hisashi Fujioka, Michael E. Lamm, Andrew G. Plaut, Michifumi Yamashita
Publikováno v:
The American Journal of Pathology. 172:31-36
The hallmark of IgA nephropathy (IgAN), the most common form of glomerulonephritis, is the presence of mesangial deposits containing IgA, specifically the IgA1 subclass, as the most prominent component. The deposited IgA is considered to be part of a