Zobrazeno 1 - 10
of 36
pro vyhledávání: '"Steven N Leonard"'
Publikováno v:
PLoS ONE, Vol 11, Iss 8, p e0160728 (2016)
Contaminated hospital surfaces are an important source of nosocomial infections. A major obstacle in marketing antimicrobial surfaces is a lack of efficacy data based on standardized testing protocols.We compared the efficacy of multiple testing prot
Externí odkaz:
https://doaj.org/article/7742e3e217f1432eb41081ab36ec9f9a
Publikováno v:
PLoS ONE, Vol 9, Iss 10, p e111250 (2014)
BACKGROUND: The use of tablet computers and other touch screen technology within the healthcare system has rapidly expanded. It has been reported that these devices can harbor pathogens in hospitals; however, much less is known about what pathogens t
Externí odkaz:
https://doaj.org/article/6b53237ccfeb4fdcbbb113286d12e366
Autor:
Steven N Leonard
Publikováno v:
PLoS ONE, Vol 7, Iss 7, p e42103 (2012)
INTRODUCTION: Continued pressure from glycopeptide use has led to non-susceptible strains of Staphylococcus aureus including heterogeneously vancomycin-intermediate S. aureus (hVISA). Infections with hVISA are associated with poor patient outcomes, t
Externí odkaz:
https://doaj.org/article/44985782fc654c6a9d295305a351dff4
Publikováno v:
Clinical Therapeutics. 36:1334-1344
Purpose Synergy between β-lactams and vancomycin against methicillin-resistant Staphylococcus aureus (MRSA) and vancomycin-intermediate Staphylococcus aureus (VISA) has been observed in vitro and in vivo. However, studies investigating piperacillin-
Autor:
Brian A. Potoski, Thomas P. Lodise, Nimish Patel, Anthony M. Casapao, Kerry L. LaPlante, Michael J. Rybak, Debra A. Goff, Steven N. Leonard, Susan L. Davis
Publikováno v:
Antimicrobial Agents and Chemotherapy. 57:4252-4259
The prevalence of heterogeneous vancomycin-intermediate Staphylococcus aureus (hVISA) infections varies in the literature, a problem complicated by the lack of routine screening procedures; however, limited data suggest that hVISA has been associated
Publikováno v:
Antimicrobial Agents and Chemotherapy. 57:2678-2683
Beta-lactams enhance the killing activity of vancomycin. Due to structural and mechanistic similarities between vancomycin and telavancin, we investigated the activity of telavancin combined with nafcillin and imipenem compared to the known synergist
Autor:
Kiri M. Rolek, Steven N. Leonard
Publikováno v:
Journal of Antimicrobial Chemotherapy. 68:644-647
OBJECTIVES Continued selective pressure from glycopeptide use has led to non-susceptible strains of Staphylococcus aureus, including vancomycin-intermediate S. aureus (VISA). Though relatively uncommon, VISA presents a particularly difficult clinical
Publikováno v:
International Journal of Antimicrobial Agents. 37:558-561
Selective pressure from glycopeptide use has led to non-susceptible strains of Staphylococcus aureus, including heterogeneously vancomycin-intermediate S. aureus (hVISA). Treatment of hVISA infections with vancomycin has been associated with treatmen
Autor:
George Delgado, Susan L. Davis, Ravina Kullar, Jason M. Pogue, Krista Wahby, Bonnie A. Falcione, Michael J. Rybak, Steven N. Leonard
Publikováno v:
Pharmacotherapy. 31:441-448
Study Objective. To assess and validate the effectiveness of a newly constructed vancomycin dosing nomogram in achieving target trough serum concentrations of 15–20 mg/L. Design. Prospective multicenter study. Setting. Five tertiary care teaching h
Autor:
Star L Rong, Steven N. Leonard
Publikováno v:
Annals of Pharmacotherapy. 44:844-850
OBJECTIVE: To provide an overview of heterogeneously glycopeptide intermediate Staphylococcus aureus, its epidemiology, methods of diagnosis, and clinical relevance. DATA SOURCES: Literature was retrieved in December 2009 through Academic Search Prem