Zobrazeno 1 - 10
of 237
pro vyhledávání: '"Steven N, Austad"'
Autor:
Harper S. Kim, Danitra J. Parker, Madison M. Hardiman, Erin Munkácsy, Nisi Jiang, Aric N. Rogers, Yidong Bai, Colin Brent, James A. Mobley, Steven N. Austad, Andrew M. Pickering
Publikováno v:
Nature Communications, Vol 14, Iss 1, Pp 1-15 (2023)
Abstract Protein translation (PT) declines with age in invertebrates, rodents, and humans. It has been assumed that elevated PT at young ages is beneficial to health and PT ends up dropping as a passive byproduct of aging. In Drosophila, we show that
Externí odkaz:
https://doaj.org/article/9b7c7453c2704f3090c9123524769e52
Autor:
Steven N. Austad, Scott Ballinger, Thomas W. Buford, Christy S. Carter, Daniel L. Smith, Jr., Victor Darley-Usmar, Jianhua Zhang
Publikováno v:
Acta Pharmaceutica Sinica B, Vol 12, Iss 2, Pp 511-531 (2022)
Aging is by far the most prominent risk factor for Alzheimer's disease (AD), and both aging and AD are associated with apparent metabolic alterations. As developing effective therapeutic interventions to treat AD is clearly in urgent need, the impact
Externí odkaz:
https://doaj.org/article/303bc329cf6c46dda549b830e064a1f6
Publikováno v:
Royal Society Open Science, Vol 8, Iss 8 (2021)
Costs of reproduction are seemingly ubiquitous across the animal kingdom, and these reproductive costs are generally defined by increased reproduction leading to decreases in other fitness components, often longevity. However, some recent reports que
Externí odkaz:
https://doaj.org/article/886826ebbd4b4d6cbcb22c4626e19ea8
Autor:
Daniella E. Chusyd, Nicole L. Ackermans, Steven N. Austad, Patrick R. Hof, Michelle M. Mielke, Chet C. Sherwood, David B. Allison
Publikováno v:
Frontiers in Aging, Vol 2 (2021)
Elephants are large-brained, social mammals with a long lifespan. Studies of elephants can provide insight into the aging process, which may be relevant to understanding diseases that affect elderly humans because of their shared characteristics that
Externí odkaz:
https://doaj.org/article/360bf502d815423fa2fdf74dfc90ade6
Autor:
Roshini Sathiaseelan, Bumsoo Ahn, Michael B Stout, Sreemathi Logan, Jonathan Wanagat, Hoang Van M Nguyen, Norman G Hord, Amy R Vandiver, Ramasamy Selvarani, Rojina Ranjit, Hannah Yarbrough, Anthony Masingale, Benjamin F Miller, Roman F Wolf, Steven N Austad, Arlan Richardson
Publikováno v:
The Journals of Gerontology: Series A. 78:771-779
We generated a genetically heterogenous rat model by a 4-way cross strategy using 4 inbred strains (Brown Norway [BN], Fischer 344 [F344], Lewis [LEW], and Wistar Kyoto [KY]) to provide investigators with a highly genetically diverse rat model from c
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::7d14d314dbf4c37472b4b446932ebdc9
https://doi.org/10.1093/gerona/glad056
https://doi.org/10.1093/gerona/glad056
Autor:
Stephanie A. Ruderman, Robin M. Nance, Lydia N. Drumright, Bridget M. Whitney, Andrew W. Hahn, Jimmy Ma, Lara Haidar, Sherif Eltonsy, Kenneth H. Mayer, Joseph J. Eron, Meredith Greene, William C. Mathews, Allison Webel, Michael S. Saag, Amanda L. Willig, Charles Kamen, Mary McCaul, Geetanjali Chander, Edward Cachay, William B. Lober, Chintan Pandya, Francisco Cartujano-Barrera, Stephen B. Kritchevsky, Steven N. Austad, Alan Landay, Mari M. Kitahata, Heidi M. Crane, Joseph A.C. Delaney
Publikováno v:
AIDS. 37:967-975
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::35dd9ef309e0f6dc29aa83469602e9a9
https://doi.org/10.1097/qad.0000000000003501
https://doi.org/10.1097/qad.0000000000003501
Autor:
Vince Fazekas-Pongor, Anna Péterfi, Dávid Major, Zsófia Szarvas, Monika Fekete, Adam G. Tabak, Anna Csiszar, William E. Sonntag, Steven N. Austad, Zoltan I. Ungvari
Publikováno v:
GeroScience
In laboratory mice, pituitary dwarfism caused by genetic reduction or elimination of the activity of growth hormone (GH) significantly extends lifespan. The effects of congenital pituitary dwarfism on human longevity are not well documented. To analy
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::26fc64160fd9ff3139279d4e04a7f6e9
https://doi.org/10.1007/s11357-022-00680-7
https://doi.org/10.1007/s11357-022-00680-7
Autor:
Edward J. Masoro, Steven N. Austad
The Handbook of the Biology of Aging, Sixth Edition, provides a comprehensive overview of the latest research findings in the biology of aging. Intended as a summary for researchers, it is also adopted as a high level textbook for graduate and upper
Autor:
Sarah R. Ocañas, Victor A. Ansere, Kyla B. Tooley, Niran Hadad, Ana J. Chucair-Elliott, David R. Stanford, Shannon Rice, Benjamin Wronowski, Kevin D. Pham, Jessica M. Hoffman, Steven N. Austad, Michael B. Stout, Willard M. Freeman
Publikováno v:
Molecular Neurobiology. 59:4669-4702
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::36764912db4661a717d62860b4f14a93
https://doi.org/10.1007/s12035-022-02860-0
https://doi.org/10.1007/s12035-022-02860-0